CHARACTERIZATION OF THE MULTIDRUG EFFLUX TRANSPORTER STYMDTMFROM SALMONELLA ENTERICA SEROVAR TYPHI

ABSTRACT Salmonellae are foodborne pathogens and the major cause of gastroenteritis in humans. Salmonellae express multidrug efflux...

COMPARATIVE PROTEIN STRUCTURE NETWORK ANALYSIS ON 3CLPRO FROM SARS‐COV‐1 AND SARS‐COV‐2

Abstract The main protease M pro , 3CL pro is an important target from coronaviruses. In spite of having 96% sequence identity among...

 
 
 

SCLPRED‐MEM: SUBCELLULAR LOCALIZATION PREDICTION OF MEMBRANE PROTEINS BY DEEP N‐TO‐1 CONVOLUTIONAL NEURAL NETWORKS

ABSTRACT The knowledge of the subcellular location of a protein is a valuable source of information in genomics, drug design and various...

RECENT ADVANCES OF DENDRIMER IN TARGETED DELIVERY OF DRUGS AND GENES TO STEM CELLS AS CELLULAR VEHICLES

Abstract Stem cells can be used to repair dysfunctional and injured tissues by delivering therapeutics. However, in comparison with...

 
 
 

FUNGAL ICE2P IS IN THE SAME SUPERFAMILY AS SERINCS, RESTRICTION FACTORS FOR HIV AND OTHER VIRUSES

Abstract Ice2p is an integral endoplasmic reticulum membrane protein in budding yeast S. cerevisiae named ICE because it is required...

DELLA PROTEINS BNAA6.RGA AND BNAC7.RGA NEGATIVELY REGULATE FATTY ACID BIOSYNTHESIS BY INTERACTING WITH BNALEC1S IN BRASSICA NAPUS

Abstract Seed oil content and fatty acid composition determine the quality and economic value of rapeseed. Little is known about the...

 
 
 

RIBOFLAVIN FORTIFICATION OF RICE ENDOSPERM BY METABOLIC ENGINEERING

Abstract Riboflavin is an essential nutrient for human health and body development. Riboflavin deficiency may increase the risk of...

NOVEL ANTIMICROBIAL ANIONIC CECROPINS FROM THE SPRUCE BUDWORM FEATURE A POLY‐L‐ASPARTIC ACID C‐TERMINUS

Abstract Cecropins form a family of amphipathic α‐helical cationic peptides with broad‐spectrum antibacterial properties and potent...

 
 
 

ALPHAFOLD2 PREDICTS THE INWARD‐FACING CONFORMATION OF THE MULTIDRUG TRANSPORTER LMRP

Abstract As part of the CASP competition, the protein structure prediction algorithm AlphaFold2 generated multiple models of the proton/drug...

ACE2‐BASED DECOY RECEPTORS FOR SARS CORONAVIRUS 2

Abstract SARS‐CoV‐2 is neutralized by proteins that block receptor‐binding sites on spikes that project from the viral envelope. In...

 
 
 

PROSPECTIVE INFERENCE OF BIOPROCESS CELL VIABILITY THROUGH CHEMOMETRIC MODELING OF FLUORESCENCE MULTIWAY DATA

Abstract In this investigation, the fermentation step of a standard mammalian cell‐based industrial bioprocess for the production of...

NEW TYROSINASES WITH PUTATIVE ACTION AGAINST CONTAMINANTS OF EMERGING CONCERN

Abstract Tyrosinases are type‐3 copper metalloenzymes with strong oxidative capacities and low allosteric selectivity to phenolic and...

 
 
 

THE MIR164‐GHCUC2‐GHBRC1 MODULE REGULATES PLANT ARCHITECTURE THROUGH ABSCISIC ACID IN COTTON

Summary Branching determines cotton architecture and production, but the underlying regulatory mechanisms remain unclear. Here, we...

ESTABLISHMENT OF AN AGROBACTERIUM‐MEDIATED GENETIC TRANSFORMATION AND CRISPR/CAS9‐MEDIATED TARGETED MUTAGENESIS IN HEMP

Summary Hemp is an annual and typically dioecious crop. Due to the therapeutic potential for human diseases, phytocannabinoids as a...

 
 
 

CHORUS2: DESIGN OF GENOME‐SCALE OLIGONUCLEOTIDE‐BASED PROBES FOR FLUORESCENCE IN SITU HYBRIDIZATION

Summary Oligonucleotide ‐fluorescence in situ hybridization has rapidly becoming the new generation of FISH technique in plant molecular...

HYDROLYSIS OF LIGNOCELLULOSE BY ANAEROBIC FUNGI PRODUCES FREE SUGARS AND ORGANIC ACIDS FOR TWO‐STAGE FINE CHEMICAL PRODUCTION WITH KLUYVEROMYCES MARXIANUS

Abstract Development of the bioeconomy is driven by our ability to access the energy‐rich carbon trapped in recalcitrant plant materials....

 
 
 

EVIDENCE FOR THE PREFERENTIAL REUSE OF SUB‐DOMAIN MOTIFS IN PRIMORDIAL PROTEIN FOLDS

Abstract A comparison of protein backbones makes clear that not more than approximately 1400 different folds exist, each specifying...

PRECLINICAL DEVELOPMENT OF PLANT‐BASED ORAL IMMUNE MODULATORY THERAPY FOR HEMOPHILIA B

Summary Anti‐drug antibody formation is a major complication in treatment of the X‐linked bleeding disorder hemophilia B. Current clinical...

 
 
 

BULKED SEGREGANT CGT‐SEQ‐FACILITATED MAP‐BASED CLONING OF A POWDERY MILDEW RESISTANCE GENE ORIGINATING FROM WILD EMMER WHEAT

Abstract Powdery mildew, caused by Blumeria graminis f. sp. tritici , is a widely occurring foliar diseases of wheat worldwide. Wild...

THE MYB FAMILY TRANSCRIPTION FACTOR TUODORANT1 FROM TRITICUM URARTU AND THE HOMOLOG TAODORANT1 FROM TRITICUM AESTIVUM INHIBIT SEED STORAGE PROTEIN SYNTHESIS IN WHEAT

Summary Seed storage proteins are determinants of wheat end‐product quality. SSP synthesis is mainly regulated at the transcriptional...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

PEPPRO: quality control and processing of nascent RNA profiling data

Nascent RNA profiling is growing in popularity; however, there is no standard analysis pipeline to uniformly process the data and assess quality. Here, we introduce PEPPRO, a... Read more ...

Enhanced cercosporin production by co-culturing Cercospora sp. JNU001 with...

Owing to the excellent properties of photosensitization, cercosporin, one of naturally occurring perylenequinonoid pigments, has been widely used in photodynamic therapy, or as... Read more ...

IAmScience Kulbir Sandhu

IAmScience Kulbir Sandhu

By Lauren Hines | Bond LSC Kulbir Sandhu's curiosity had guided him from place to place, but it was his fascination with plant science that has stayed the same. While Sandhu... Read more ...

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most produce antibodies in response to a pathogen or a vaccine. A small subset of B cells instead... Read more ...

Identifying collateral and synthetic lethal vulnerabilities within the...

A pair of genes is defined as synthetically lethal if defects on both cause the death of the cell but a defect in only one of the two is compatible with cell viability... Read more ...

Scientist - Emergent Biosolutions - San Diego, CA

The Scientist position supports the R&D teams to achieve company pipeline objectives by conducting research assignments involving a variety of laboratory...From Emergent... Read more ...

SSBER: removing batch effect for single-cell RNA sequencing data

With the continuous maturity of sequencing technology, different laboratories or different sequencing platforms have generated a large amount of single-cell transcriptome... Read more ...

Antimalarial Drug Resistance and Implications for the WHO Global Technical...

Abstract Purpose of Review Five years have passed since the World Health Organization released its Global Technical Strategy for Malaria. In that time, progress against malaria... Read more ...

Chloroplast genome analysis of Angiosperms and phylogenetic relationships...

Abstract Availability of comprehensive phylogenetic tree for flowering plants which includes many of the economically important crops and trees is one of the essential... Read more ...

Sr. Custom Applications Scientist - BD - San Diego, CA

Advanced design and development of assays including flow cytometry assays for assessment of cellular response to changes in the normal physiological make-up.From BD - Sat, 15... Read more ...