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Sustainable Polysaccharide Hydrogels Based on Dynamic Schiff Base Linkages as Versatile Building Blocks for Fabricating Advanced Functional Materials

Posted On: Mar 21, 2023   |   Posted By: Springer

Abstract
Polysaccharides are an idiosyncratic source of organic natural materials apropos structural diversity, functionalities, and abundance. In their indigenous state, few of their functionalities inhabit their material form as hydrogels, consequently proffering molecular tactics to be exploited. Recently, polysaccharide-based hydrogels utilizing the Schiff base bonds or dynamic imine chemistry as crosslinks have been widely explored owing to their high sensitivity, good flexibility, enhanced recyclability, stimuli-responsiveness, and tissue adhesion. The polysaccharide-derived Schiff base hydrogels bestow elementary fabrication, self-healing properties, and injectibility under physiological conditions, resulting in mechanical forces that result in the augmentation of gel precursors. These hierarchical constructs can be tuned for mechanically, morphologically, and biochemically different microenvironments, thus finding numerous applications in a variety of fields. Herein, we comprehensively analyze the...

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