Springer

ALTERNATIVE SPLICING: A NEW BREAKTHROUGH FOR UNDERSTANDING TUMORIGENESIS AND POTENTIAL CLINICAL APPLICATIONS

Abstract Background Alternative splicing is a post-transcriptional process that produces transcript variants, thus leading to transcriptome...

ZIM3 ACTIVATION OF CCL25 EXPRESSION IN PULMONARY METASTATIC NODULES OF OSTEOSARCOMA RECRUITS M2 MACROPHAGES TO PROMOTE METASTATIC GROWTH

Abstract Tumor-associated macrophages play an important role in tumor growth and metastasis. However, the involvement of TAMs infiltration...

ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING DISCIPLINES WITH THE POTENTIAL TO IMPROVE THE NANOTOXICOLOGY AND NANOMEDICINE FIELDS: A COMPREHENSIVE REVIEW

Abstract The use of nanomaterials in medicine depends largely on nanotoxicological evaluation in order to ensure safe application on...

DIVERSITY OF VIROIDS INFECTING GRAPEVINES IN THE SOUTH AFRICAN VITIS GERMPLASM COLLECTION

Abstract Seven viroid species and one putative viroid species have been reported to infect grapevine namely, hop stunt viroid , grapevine...

1Α,25-DIHYDROXYVITAMIN D3 REGULATES MICRORNA PACKAGING IN EXTRACELLULAR MATRIX VESICLES AND THEIR RELEASE IN THE MATRIX

Abstract Growth plate chondrocytes are regulated by numerous factors and hormones as they mature during endochondral bone formation,...

MOLECULAR ANALYSIS AND SEX-SPECIFIC RESPONSE OF THE HEPCIDIN GENE IN YELLOW PERCH FOLLOWING LIPOPOLYSACCHARIDE CHALLENGE

Abstract Hepcidin antimicrobial peptide is active in teleosts against invading pathogens and plays important roles in the stress and...

CORRECTION TO: INVOLVEMENT OF TRPM2 CHANNEL ON DOXORUBICIN-INDUCED EXPERIMENTAL CARDIOTOXICITY MODEL: PROTECTIVE ROLE OF SELENIUM

A COMMENTARY ON: SERUM TRACE ELEMENT CONCENTRATIONS IN RHEUMATOID ARTHRITIS

STUDY ON THE CORRELATION BETWEEN REGULATORY PROTEINS OF N6-METHYLADENOSINE AND OXIDATIVE DAMAGE IN CADMIUM-INDUCED RENAL INJURY

Abstract As a common environmental heavy metal pollutant, cadmium has been well evidenced to cause kidney damage; yet, the underlying...

ASSOCIATION OF BLOOD SELENIUM LEVEL WITH ESTIMATED GLOMERULAR FILTRATION RATE IN THE AGING POPULATION: A CROSS-SECTIONAL STUDY

Abstract The relationship between blood selenium level and estimated glomerular filtration rate had been explored in previous studies....

ESTIMATION OF CALCIUM TITANATE OR ERBIUM OXIDE NANOPARTICLES INDUCED CYTOTOXICITY AND GENOTOXICITY IN NORMAL HSF CELLS

Abstract Extensive uses of calcium titanate nanoparticles and erbium oxide nanoparticles increase their release into the environment...

BORON-CONTAINING COMPOUNDS FOR PREVENTION, DIAGNOSIS, AND TREATMENT OF HUMAN METABOLIC DISORDERS

Abstract The application of natural and synthetic boron-containing compounds in biomedical field is expanding. BCC have effects in...

INVESTIGATIONS FOR VIBRATION AND FRICTION TORQUE BEHAVIORS OF THRUST BALL BEARING WITH SELF-DRIVEN TEXTURED GUIDING SURFACE

Abstract In order to improve the starved lubrication condition of rolling bearings, three kinds of textures, namely dimple, groove...

ADVANCES AND APPLICATIONS OF MACHINE LEARNING AND INTELLIGENT OPTIMIZATION ALGORITHMS IN GENOME-SCALE METABOLIC NETWORK MODELS

Abstract Due to the increasing demand for microbially manufactured products in various industries, it has become important to find...

HUMAN PAPILLOMAVIRUS INTEGRATION SIGNATURE IN CERVICAL LESIONS: IDENTIFICATION OF MACROD2 GENE AS HPV HOT SPOT INTEGRATION SITE

Abstract Background High-risk HPV is clearly associated with cervical cancer. Integration of HPV DNA into the host genome is considered...

BIOSYNTHESIS AND TRANSFER OF 2-ACETAMIDO-4-METHYLAMINO-L-FUCOSE TO THE CORE-LIPID A IN BORDETELLA PERTUSSIS

Abstract The trisaccharide unit in lipopolysaccharide of Bordetella pertussis is important for immune recognition, but how the rare...

THE EFFECTS OF A MIXTURE OF CADMIUM, LEAD, AND MERCURY ON METABOLIC SYNDROME AND ITS COMPONENTS, AS WELL AS COGNITIVE IMPAIRMENT: GENES, MICRORNAS, TRANSCRIPTION FACTORS, AND SPONGE RELATIONSHIPS

Abstract Converging evidence indicates heavy metal-induced genes, transcription factors , and microRNAs are critical pathological components...

A PARTIAL ORDER FRAMEWORK FOR INCOMPLETE DATA CLUSTERING

Abstract We propose in this paper a partial order framework for clustering incomplete data. The paramount feature of this framework...

RETINAL PATHOLOGICAL FEATURES AND PROTEOME SIGNATURES OF ALZHEIMER'S DISEASE

Abstract Alzheimer's disease pathologies were discovered in the accessible neurosensory retina. However, their exact nature and topographical...

EXPRESSION OF B LYMPHOCYTE-INDUCED MATURATION PROTEIN 1 IN KERATINOCYTE AND CYTOKINE SIGNALLING DRIVES HUMAN TH17 RESPONSE IN PSORIASIS

Abstract Transcriptional factor B lymphocyte-induced maturation protein 1 is pivotally implicated in T helper 17 cell differentiation....