STRONG: METAGENOMICS STRAIN RESOLUTION ON ASSEMBLY GRAPHS

We introduce STrain Resolution ON assembly Graphs , which identifies strains de novo, from multiple metagenome samples. STRONG performs...

ENABLING REPRODUCIBLE RE-ANALYSIS OF SINGLE-CELL DATA

 
 
 

DISSECTING INDIRECT GENETIC EFFECTS FROM PEERS IN LABORATORY MICE

The phenotype of an individual can be affected not only by the individual's own genotypes, known as direct genetic effects , but also...

DETOKI IDENTIFIES AND CHARACTERIZES THE DYNAMICS OF CHROMATIN TAD-LIKE DOMAINS IN A SINGLE CELL

Topologically associating domains are a key structure of the 3D mammalian genomes. However, the prevalence and dynamics of TAD-like...

 
 
 

MEGALMM: MEGA-SCALE LINEAR MIXED MODELS FOR GENOMIC PREDICTIONS WITH THOUSANDS OF TRAITS

Large-scale phenotype data can enhance the power of genomic prediction in plant and animal breeding, as well as human genetics. However,...

HAPLOFLOW: STRAIN-RESOLVED DE NOVO ASSEMBLY OF VIRAL GENOMES

 
 
 

THE GENETIC ARCHITECTURE OF TEMPERATURE ADAPTATION IS SHAPED BY POPULATION ANCESTRY AND NOT BY SELECTION REGIME

Understanding the genetic architecture of temperature adaptation is key for characterizing and predicting the effect of climate change...

PUBLISHER CORRECTION: LEVERAGING BREEDING PROGRAMS AND GENOMIC DATA IN NORWAY SPRUCE FOR GWAS ANALYSIS

 
 
 

GENOMIC DIVERSITY AND ECOLOGY OF HUMAN-ASSOCIATED AKKERMANSIA SPECIES IN THE GUT MICROBIOME REVEALED BY EXTENSIVE METAGENOMIC ASSEMBLY

Akkermansia muciniphila is a human gut microbe with a key role in the physiology of the intestinal mucus layer and reported associations...

GRIDSS2: COMPREHENSIVE CHARACTERISATION OF SOMATIC STRUCTURAL VARIATION USING SINGLE BREAKEND VARIANTS AND STRUCTURAL VARIANT PHASING

GRIDSS2 is the first structural variant caller to explicitly report single breakends-breakpoints in which only one side can be unambiguously...

 
 
 

TELOMERE-TO-TELOMERE ASSEMBLY OF A FISH Y CHROMOSOME REVEALS THE ORIGIN OF A YOUNG SEX CHROMOSOME PAIR

The origin of sex chromosomes requires the establishment of recombination suppression between the proto-sex chromosomes. In many fish...

AUTHOR CORRECTION: IMPROVED REFERENCE GENOME OF THE ARBOVIRAL VECTOR AEDES ALBOPICTUS

 
 
 

TRANSCRIPTION-COUPLED STRUCTURAL DYNAMICS OF TOPOLOGICALLY ASSOCIATING DOMAINS REGULATE REPLICATION ORIGIN EFFICIENCY

Metazoan cells only utilize a small subset of the potential DNA replication origins to duplicate the whole genome in each cell cycle....

REVEALING THE FULL BIOSPHERE STRUCTURE AND VERSATILE METABOLIC FUNCTIONS IN THE DEEPEST OCEAN SEDIMENT OF THE CHALLENGER DEEP

The full biosphere structure and functional exploration of the microbial communities of the Challenger Deep of the Mariana Trench,...

 
 
 

2DFDR: A NEW APPROACH TO CONFOUNDER ADJUSTMENT SUBSTANTIALLY INCREASES DETECTION POWER IN OMICS ASSOCIATION STUDIES

One challenge facing omics association studies is the loss of statistical power when adjusting for confounders and multiple testing....

THE EVOLVING GENE REGULATORY LANDSCAPE-A TINKERER OF COMPLEX CREATURES

 
 
 

ELEVATED RETROTRANSPOSON ACTIVITY AND GENOMIC INSTABILITY IN PRIMED PLURIPOTENT STEM CELLS

Naïve and primed pluripotent stem cells represent two different pluripotent states. Primed PSCs following in vitro culture exhibit...

INTEGRATION OF METABOLOMICS, GENOMICS, AND IMMUNE PHENOTYPES REVEALS THE CAUSAL ROLES OF METABOLITES IN DISEASE

Recent studies highlight the role of metabolites in immune diseases, but it remains unknown how much of this effect is driven by genetic...

 
 
 

COORDINATED CHANGES IN GENE EXPRESSION KINETICS UNDERLIE BOTH MOUSE AND HUMAN ERYTHROID MATURATION

Single-cell technologies are transforming biomedical research, including the recent demonstration that unspliced pre-mRNA present in...

CLIMB-COVID: CONTINUOUS INTEGRATION SUPPORTING DECENTRALISED SEQUENCING FOR SARS-COV-2 GENOMIC SURVEILLANCE

In response to the ongoing SARS-CoV-2 pandemic in the UK, the COVID-19 Genomics UK consortium was formed to rapidly sequence SARS-CoV-2...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

MicroRNA-17-5p Promotes Cardiac Hypertrophy by Targeting Mfn2 to Inhibit...

Abstract Pathological cardiac hypertrophy is the leading cause of heart failure, and miRNAs have been recognized as key factors in cardiac hypertrophy. This study aimed to... Read more ...

Scientist, Hematologic and Immunologic Toxicology - La Jolla, CA - Johnson &...

As part of the cutting-edge Global Predictive, Investigative and Translational Toxicology Team, the candidate will have the opportunity to work within...From Johnson & Johnson... Read more ...

Bringing Protection Back in Line

Bringing Protection Back in Line

Research refines platform to address immune disorders Dr. Esma Yolcu and Dr. Haval Shirwan, Co-pioneers of ProtEx technology By Davis Suppes | Bond LSC The things that protect... Read more ...

After 40 Years, HIV Presents Research Problems New and Old

After 40 Years, HIV Presents Research Problems New and Old

In the years since AIDS was first described in medical research, the scientific map of that disease has changed enormously. Once it was relatively empty. Now scientists... Read more ...

Exosomal circRNA HIPK3 knockdown inhibited cell proliferation and metastasis...

Abstract Prostate cancer is the second frequent malignancy among men in the world. Exosomal circular RNAs have been reported to function in PCa progression. The current study... Read more ...

Prognostic value and immunological characteristics of a novel...

Abstract Autophagy affects the development, progression, and prognosis of various cancers including pancreatic cancer. To develop an autophagy-related prognostic model of... Read more ...

Chiral nanomaterials for tumor therapy: autophagy, apoptosis, and...

Chirality is a fundamental characteristic of natural molecules and a crucial factor in the biochemical reactions of living cells and organisms. Recently, researchers have... Read more ...

Ramil the snow leopard tests positive for COVID at the San Diego Zoo

Zoo staff say the animal's symptoms are mild and are still investigating how he got infected Read more ...

Enhanced lignin biodegradation by consortium of white rot fungi: microbial...

As one of the major components of lignocellulosic biomass, lignin has been considered as the most abundant renewable aromatic feedstock in the world. Comparing with thermal or... Read more ...

Design and heterologous expression of a novel dimeric LL37 variant in Pichia...

The antimicrobial peptide LL37 is produced by white blood cells and various epithelial cells, and has the outstanding advantages of participating in immune regulation, causing... Read more ...