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BMC Bioinformatics

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TRANSFER LEARNING FOR GENOTYPE-PHENOTYPE PREDICTION USING DEEP LEARNING MODELS

For some understudied populations, genotype data is minimal for genotype-phenotype prediction. However, we can use the data of some...

CHIMERA: AN EASY TO USE PIPELINE FOR BACTERIAL GENOME BASED METABOLIC NETWORK RECONSTRUCTION, EVALUATION AND VISUALIZATION

Genome-scale metabolic reconstruction tools have been developed in the last decades. They have helped to reconstruct eukaryotic and...

 
 
 

PERSISTENT MEMORY AS AN EFFECTIVE ALTERNATIVE TO RANDOM ACCESS MEMORY IN METAGENOME ASSEMBLY

The assembly of metagenomes decomposes members of complex microbe communities and allows the characterization of these genomes without...

SCALABLE TRANSCRIPTOMICS ANALYSIS WITH DASK: APPLICATIONS IN DATA SCIENCE AND MACHINE LEARNING

Gene expression studies are an important tool in biological and biomedical research. The signal carried in expression profiles helps...

 
 
 

MATHEMATICAL MODEL OF THE CELL SIGNALING PATHWAY BASED ON THE EXTENDED BOOLEAN NETWORK MODEL WITH A STOCHASTIC PROCESS

In cell signaling pathways, proteins interact with each other to determine cell fate in response to either cell-extrinsic or intrinsic...

MP4: A MACHINE LEARNING BASED CLASSIFICATION TOOL FOR PREDICTION AND FUNCTIONAL ANNOTATION OF PATHOGENIC PROTEINS FROM METAGENOMIC AND GENOMIC DATASETS

Bacteria can exceptionally evolve and develop pathogenic features making it crucial to determine novel pathogenic proteins for specific...

 
 
 

IDMET: NETWORK-BASED APPROACH FOR INTEGRATING DIFFERENTIAL ANALYSIS OF CANCER METABOLOMICS

Comprehensive metabolomic analyses have been conducted in various institutes and a large amount of metabolomic data are now publicly...

EARLY EFFECTS OF GENE DUPLICATION ON THE ROBUSTNESS AND PHENOTYPIC VARIABILITY OF GENE REGULATORY NETWORKS

Research on gene duplication is abundant and comes from a wide range of approaches, from high-throughput analyses and experimental...

 
 
 

OPTIMAL CONSTRUCTION OF A FUNCTIONAL INTERACTION NETWORK FROM POOLED LIBRARY CRISPR FITNESS SCREENS

Functional interaction networks, where edges connect genes likely to operate in the same biological process or pathway, can be inferred...

DEEP LEARNING AND MULTI-OMICS APPROACH TO PREDICT DRUG RESPONSES IN CANCER

Cancers are genetically heterogeneous, so anticancer drugs show varying degrees of effectiveness on patients due to their differing...

 
 
 

RECONSTRUCTING GENE REGULATORY NETWORKS OF BIOLOGICAL FUNCTION USING DIFFERENTIAL EQUATIONS OF MULTILAYER PERCEPTRONS

Building biological networks with a certain function is a challenge in systems biology. For the functionality of small biological networks,...

SITEPATH: A VISUAL TOOL TO IDENTIFY POLYMORPHISM CLADES AND HELP FIND FIXED AND PARALLEL MUTATIONS

Identifying polymorphism clades on phylogenetic trees could help detect punctual mutations that are associated with viral functions....

 
 
 

WGDTREE: A PHYLOGENETIC SOFTWARE TOOL TO EXAMINE CONDITIONAL PROBABILITIES OF RETENTION FOLLOWING WHOLE GENOME DUPLICATION EVENTS

Multiple processes impact the probability of retention of individual genes following whole genome duplication events. In analyzing...

A GRAPH NEURAL NETWORK FRAMEWORK FOR MAPPING HISTOLOGICAL TOPOLOGY IN ORAL MUCOSAL TISSUE

Histological feature representation is advantageous for computer aided diagnosis and disease classification when using predictive techniques...

 
 
 

TRANSPOSABLE ELEMENT FINDER : FINDING ACTIVE TRANSPOSABLE ELEMENTS FROM NEXT GENERATION SEQUENCING DATA

Detection of newly transposed events by transposable elements from next generation sequence data is difficult, due to their multiple...

BIOBYGANS: BIOMEDICAL NAMED ENTITY RECOGNITION BY FUSING CONTEXTUAL AND SYNTACTIC FEATURES THROUGH GRAPH ATTENTION NETWORK IN NODE CLASSIFICATION FRAMEWORK

Automatic and accurate recognition of various biomedical named entities from literature is an important task of biomedical text mining,...

 
 
 

ACCURATE GENOME-WIDE PHASING FROM IBD DATA

As genotype databases increase in size, so too do the number of detectable segments of identity by descent : segments of the genome...

USAT: A BIOINFORMATIC TOOLKIT TO FACILITATE INTERPRETATION AND COMPARATIVE VISUALIZATION OF TANDEM REPEAT SEQUENCES

Tandem repeats , highly variable genomic variants, are widely used in individual identification, disease diagnostics, and evolutionary...

 
 
 

H3AGWAS: A PORTABLE WORKFLOW FOR GENOME WIDE ASSOCIATION STUDIES

Genome-wide association studies are a powerful method to detect associations between variants and phenotypes. A GWAS requires several...

SESAM: SOFTWARE FOR AUTOMATIC CONSTRUCTION OF ORDER-ROBUST LINKAGE MAPS

Genotyping and sequencing technologies produce increasingly large numbers of genetic markers with potentially high rates of missing...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Oncolytics Biotech® Receives FDA Fast Track Designation for the Treatment of...

FDA Fast Track designation granted after presentation at the SITC 37th Annual Meeting demonstrating 69% objective response rate SAN DIEGO, and CALGARY, AB, Dec. 1, 2022... Read more ...

Research Associate - WuXi AppTec Inc - San Diego, CA

Works on routine assignments per written procedures, where ability to recognize deviation from accepted practice is required. High school or... Read more ...

Genetic engineering of complex feed enzymes into barley seed for direct...

Summary Currently, feed enzymes are primarily obtained through fermentation of fungi, bacteria, and other microorganisms. Although the manufacturing technology for feed enzymes... Read more ...

Sr. Scientist - Conjugation Protein Sciences - Elite Protek - La Jolla, CA

Ph.D in Biology/Chemistry or related discipline. 2-5 years supporting ADC projects in early research preferred.From Indeed -... Read more ...

Research Associate/Scientist, Pharmaceutics & Formulation Research - AKCEA...

Provide scientific and technical leadership on one or more areas of formulation development and dosage form design.From AKCEA Therapeutics -... Read more ...

Transmission of Poly Single‐Stranded DNA through Polycarbonate Track‐Etched...

Abstract The objective of this study was to examine membrane filtration of a single stranded DNA with 60 thymine nucleotides, and to elucidate the variables controlling its... Read more ...

Carbon fiber cannot always reduce the wear of PEEK for orthopedic implants...

Abstract Excellent wear resistance is an important feature of orthopedic implants. However, although pure polyetheretherketone is outperformed by carbon fiber-reinforced PEEK... Read more ...

Synthesis of N-doped carbon quantum dots as lubricant additive to enhance...

Abstract In this study, a novel lubricant additive nitrogen-doped carbon quantum dot nanoparticle was prepared by the solvothermal method. The synthesized spherical N-CQD... Read more ...

Two-dimensional molybdenum carbide as an efficient nanoadditive for...

Abstract In this study, a robust macroscale liquid superlubricity with a coefficient of friction of 0.004 was achieved by introducing molybdenum carbide MXene nanoparticles as... Read more ...

Dopamine-triggered one-step functionalization of hollow silica nanospheres...

Abstract Osteoarthritis has been regarded as a lubrication deficiency related joint disease. Combination of both joint lubrication and drug intervention may provide a promising... Read more ...