Vertex Stops Test of Rare Disease Drug, Dimming Pipeline Prospects

VERTEX STOPS TEST OF RARE DISEASE DRUG, DIMMING PIPELINE PROSPECTS

Vertex Pharmaceuticals is halting work on an experimental drug for a rare protein deficiency after safety problems were reported in...

Sanofi, Pfizer & Bristol Drugs Among the 12 Approvals to Look Out for in Q4

SANOFI, PFIZER & BRISTOL DRUGS AMONG THE 12 APPROVALS TO LOOK OUT FOR IN Q4

The end of the year should see a flurry of new products reaching the market to break new commercial ground or shake up their respective...

 
 
 
Roche Enlists Dyno to Bring AI to Next-Generation Liver, CNS Gene Therapies

ROCHE ENLISTS DYNO TO BRING AI TO NEXT-GENERATION LIVER, CNS GENE THERAPIES

Roche made a splash with its acquisition of Spark Therapeutics, whose Luxturna, a gene therapy for an inherited form of vision loss,...

Codiak Bio's IPO Brings In $82M as Exosome Clinical Trials Begin

CODIAK BIO'S IPO BRINGS IN $82M AS EXOSOME CLINICAL TRIALS BEGIN

Codiak BioSciences now has $82.5 million to fund clinical tests of a new class of medicines based on exosomes, tiny bubbles formed...

 
 
 
Despite Phase 2 Failure, Gossamer Bio Sees a Path for Drug in Asthma

DESPITE PHASE 2 FAILURE, GOSSAMER BIO SEES A PATH FOR DRUG IN ASTHMA

Gossamer Bio's lead drug, an experimental treatment for asthma and allergies, has failed in two mid-stage clinical trials but the biotech...

SQZ Biotech Lines Up an IPO on the NYSE to Fund Cell Therapy R&D

SQZ BIOTECH LINES UP AN IPO ON THE NYSE TO FUND CELL THERAPY R&D

SQZ Biotechnologies, which already has an alliance with Roche focused on developing new cancer cell therapies, is now looking to sell...

 
 
 
“Opioid Stacking” Concerns Lead FDA to Reject Avenue Therapeutics Drug

“OPIOID STACKING” CONCERNS LEAD FDA TO REJECT AVENUE THERAPEUTICS DRUG

An opioid that Avenue Therapeutics reformulated for treating post-surgical pain in hospital settings has been rejected by the FDA due...

 
 
 
Bio Roundup: CRISPR Kudos, Bristol Myers's Buy, RNAi Alliance & More

BIO ROUNDUP: CRISPR KUDOS, BRISTOL MYERS'S BUY, RNAI ALLIANCE & MORE

It's October: a time of days growing shorter, leaves changing color, and phone calls in the wee hours that rouse scientists from slumber...

Biogen's AdComm Meeting Will Test FDA's “Substantial Evidence” Flexibility

BIOGEN'S ADCOMM MEETING WILL TEST FDA'S “SUBSTANTIAL EVIDENCE” FLEXIBILITY

A US Food and Drug Administration advisory committee meeting on Biogen, Inc.'s Alzheimer's drug aducanumab will offer some insight...

 
 
 
 
 
 
 
 
 
Genfit Restructuring Cuts Staff by 40%, Creates Two New Subsidiaries

GENFIT RESTRUCTURING CUTS STAFF BY 40%, CREATES TWO NEW SUBSIDIARIES

Genfit is halting all work on its lead drug in the fatty liver disorder nonalcoholic steatohepatitis and implementing a corporate restructuring...

Bristol Myers to Buy MyoKardia, FDA-Ready Heart Disease Drug for $13.1B

BRISTOL MYERS TO BUY MYOKARDIA, FDA-READY HEART DISEASE DRUG FOR $13.1B

Bristol Myers Squibb is bolstering its cardiovascular drug lineup with a $13.1 billion deal to acquire MyoKardia, a company whose experimental...

 
 
 
Bristol Myers's Hirawat on Pipeline Progress, Clinical Trial Diversity

BRISTOL MYERS'S HIRAWAT ON PIPELINE PROGRESS, CLINICAL TRIAL DIVERSITY

As the one-year anniversary of Bristol-Myers Squibb Company's $74bn acquisition of Celgene Corporation approaches, Scrip spoke with...

Bio Roundup: MESO's Miss, Pfizer's Cancer Bet, Vaccine Promise & More

BIO ROUNDUP: MESO'S MISS, PFIZER'S CANCER BET, VACCINE PROMISE & MORE

Amid the bombast of Tuesday's presidential debate, viewers caught some discussion about the response to the coronavirus pandemic and...

 
 
 
FDA Lifts Solid Bio Clinical Hold, Duchenne Study Cleared to Resume

FDA LIFTS SOLID BIO CLINICAL HOLD, DUCHENNE STUDY CLEARED TO RESUME

Solid Biosciences has answered the FDA's outstanding questions about its Duchenne muscular gene therapy, clearing a clinical trial...

Genfit Restructuring Cuts Staff by 40%, Creates Two New Subsidiaries

GENFIT RESTRUCTURING CUTS STAFF BY 40%, CREATES TWO NEW SUBSIDIARIES

Genfit is halting all work on its lead drug in the fatty liver disorder nonalcoholic steatohepatitis and implementing a corporate restructuring...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

PacBio and Invitae Team Up to Develop Ultra-High-Throughput Clinical Whole...

PacBio and Invitae Team Up to Develop Ultra-High-Throughput Clinical Whole Genome Sequencing Platform

The power of PacBio HiFi reads has enabled transformative research into human disease. A new collaboration with Invitae, a leader in medical genetics, is intended to help... Read more ...

STAT: Businesses across the vaccine supply chain must work together to make...

STAT: Businesses across the vaccine supply chain must work together to make Covid-19 vaccines

Andrey Zarur, CEO of GreenLight Biosciences, writes for STAT about the vaccine supply chain and how we need to work together to make Covid-19 vaccines. Credit: LEON NEAL/GETTY... Read more ...

IAmScience Leland Cseke

IAmScience Leland Cseke

By Becca Wolf | Bond LSC In a cluttered basement in Dearborn, Michigan, one could find Leland Cseke conducting amateur plant tissue culture experiments on his family's pool... Read more ...

Study: X-Rays Surrounding ‘Magnificent 7' May Be Traces of Sought-After Particle

Study: X-Rays Surrounding ‘Magnificent 7' May Be Traces of Sought-After Particle

An artistic rendering of the XMM-Newton space telescope. A study of archival data from the XMM-Newton and the Chandra X-ray space telescopes found evidence of high levels of... Read more ...

AnaptysBio, Inc.: Senior Scientist II

AnaptysBio, Inc.: Position Summary The candidate will play a lead role in Protein Sciences, with responsibilities to include the supervision of protein purification an San... Read more ...

Emergent BioSolutions: Senior Manager, Product Development

Emergent BioSolutions: Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect... Read more ...

MendelVar: gene prioritisation at GWAS loci using phenotypic enrichment of...

AbstractMotivationGene prioritisation at human GWAS loci is challenging due to linkage disequilibrium and long-range gene regulatory mechanisms. However, identifying the causal... Read more ...

A two-step approach to testing overall effect of gene-environment...

AbstractMotivationWhile gene-environment interactions contribute importantly to many different phenotypes, detecting such interactions requires well-powered studies and has... Read more ...

A network-based deep learning methodology for stratification of tumor mutations

AbstractMotivationTumor stratification has a wide range of biomedical and clinical applications, including diagnosis, prognosis and personalized treatment. However, cancer is... Read more ...

Recognition of small molecule-RNA binding sites using RNA sequence and structure

AbstractMotivationRNA molecules become attractive small-molecule drug targets to treat disease in recent years. Computer-aided drug design can be facilitated by detecting the... Read more ...