APPLICATION OF A KNN‐BASED SIMILARITY METHOD TO BIOPHARMACEUTICAL MANUFACTURING

Abstract Machine learning based similarity analysis is commonly found in many artificial intelligence applications like the one utilized...

VASCULAR‐SPECIFIC EXPRESSION OF GASTRODIA ANTIFUNGAL PROTEIN GENE SIGNIFICANTLY ENHANCED COTTON VERTICILLIUM WILT RESISTANCE

Abstract Verticillium wilt caused by Verticillium dahliae Kleb is the most destructive disease in cotton‐growing areas around the world,...

 
 
 

NESTED‐ASSOCIATION MAPPING BASED GENETIC DISSECTION UNCOVERS CANDIDATE GENES FOR SEED AND POD WEIGHTS IN PEANUT

Abstract Multi‐parental genetic mapping populations such as nested‐association mapping have great potential for investigating quantitative...

APPLICATION OF FERMENTATION PROCESS CONTROL TO INCREASE L‐TRYPTOPHAN PRODUCTION IN ESCHERICHIA COLI

Abstract In this study, process engineering and process control were applied to increase the production of L‐tryptophan, using Escherichia...

 
 
 

OVEREXPRESSION OF A DEVELOPING XYLEM CDNA LIBRARY IN TRANSGENIC POPLAR GENERATES HIGH MUTATION RATE SPECIFIC TO WOOD FORMATION

Abstract We investigated feasibility of the FOX (Full‐length complementary DNA OvereXpression) system as a mutagenesis approach in...

DECIPHERING THE HIGH QUALITY GENOME SEQUENCE OF CORIANDER THAT CAUSES CONTROVERSIAL FEELINGS

Abstract Coriander , a plant from the Apiaceae family, also called cilantro or Chinese parsley, is a globally important crop used as...

 
 
 

SCAFFOLD PROTEIN GHMORG1 ENHANCES THE RESISTANCE OF COTTON TO FUSARIUM OXYSPORUM BY FACILITATING THE MKK6‐MPK4 CASCADE

Abstract In eukaryotes, MAPK scaffold proteins are crucial for regulating the function of MAPK cascades. However, only a few MAPK scaffold...

INCREASED RUBISCO CONTENT IN MAIZE MITIGATES CHILLING STRESS AND SPEEDS RECOVERY

Abstract Many C 4 plants, including maize, perform poorly under chilling conditions. This phenomenon has been linked in part to decreased...

 
 
 

COARSE‐GRAINED AND ATOMIC RESOLUTION BIOMOLECULAR DOCKING WITH THE ATTRACT APPROACH

ABSTRACT The ATTRACT protein‐protein docking program has been employed to predict protein‐protein complex structures in CAPRI rounds...

BIOINFORMATIC IDENTIFICATION OF CHINESE HAMSTER OVARY COLD‐SHOCK GENES AND BIOLOGICAL EVIDENCE OF THEIR COLD‐INDUCIBLE PROMOTERS

Lower cultivation temperature dramatically affects cell growth and cellular productivity in CHO and is often used in industrial applications...

 
 
 

EXOME ASSOCIATION ANALYSIS SHEDS LIGHT ONTO LEAF RUST RESISTANCE GENES CURRENTLY USED IN WHEAT BREEDING

Abstract Resistance breeding is crucial for a sustainable control of leaf rust in wheat while directly targeting functional variants...

CKX: A GENETIC TARGET FOR YIELD IMPROVEMENT IN WHEAT

Abstract The plant hormone group, the cytokinins, are implicated in both qualitative and quantitative components of yield. Cytokinins...

 
 
 

OPTIMIZING PLANT ADENINE BASE EDITOR SYSTEMS BY MODIFYING THE TRANSGENE SELECTION SYSTEM

Abstract Classical CRISPR‐Cas systems introduce a DNA double‐strand break at target genomic loci. In plant, DSBs are typically repaired...

BIOPROCESS OPTIMIZATION OF LACCASE PRODUCTION THROUGH SOLID SUBSTRATE FERMENTATION USING PERENNIPORIA TEPHROPORA‐L168 AND ITS APPLICATION IN BIOREMEDIATION OF TRIARYL‐METHANE DYE

Abstract Laccases are multi copper oxidases that can oxidize both phenolic and nonphenolic lignin related compounds. Consequently,...

 
 
 

RESVERATROL ADDITION TO CHO CELL CULTURE MEDIA: THE EFFECT ON CELL GROWTH, MONOCLONAL ANTIBODY SYNTHESIS AND ITS CHEMICAL MODIFICATION

Abstract The effect of the addition of resveratrol to cell culture media during the production of monoclonal antibodies was investigated....

ELECTROCHEMICAL CHARACTERISTICS OF A HYPERTHERMOPHILIC ENZYME IN MICRODROPLETS STIRRED AND HEATED BY SURFACE ACOUSTIC WAVES

Abstract μTAS is expected to be applied in various fields. In particular, since electrochemical measurement is inexpensive and easy,...

 
 
 

MAMMALIAN CELL CULTIVATION USING NUTRIENTS EXTRACTED FROM MICROALGAE

Abstract Mammalian cells have been used in various research fields. More recently, cultured cells have been used as the cell source...

SH‐SY5Y AND LUHMES CELLS DISPLAY DIFFERENTIAL SENSITIVITY TO MPP+, TUNICAMYCIN AND EPOXOMICIN IN 2D AND 3D CELL CULTURE

Abstract SH‐SY5Y and LUHMES cell lines are widely used as model systems for studying neurotoxicity. Most of the existing data regarding...

 
 
 

STRUCTURE PREDICTION OF BIOLOGICAL ASSEMBLIES USING GALAXY IN CAPRI ROUNDS 38‐45

ABSTRACT We participated in CARPI rounds 38‐45 both as a server predictor and a human predictor. These CAPRI rounds provided excellent...

MULTIPLEX CRISPR/CAS9‐MEDIATED METABOLIC ENGINEERING INCREASES SOYBEAN ISOFLAVONE CONTENT AND RESISTANCE TO SOYBEAN MOSAIC VIRUS

Abstract Isoflavonoids, which include a variety of secondary metabolites, are derived from the phenylpropanoid pathway and are distributed...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

IAmScience Mannie Liscum

IAmScience Mannie Liscum

For Mannie Liscum, thinking is a privilege, and his job gives him the chance to be fascinated by human's capacity to conceptualize and learn new things. “It's my goal to use as... Read more ...

3 Takeaways From the Resurrection of Biogen's Alzheimer's Drug

3 Takeaways From the Resurrection of Biogen's Alzheimer's Drug

The name of the experimental drug was heard so frequently in hotel hallways at the conference that it sounded like an incantation: aducanumab, aducanumab, aducanumab... Read more ...

Acadia Looks to Expand Drug Beyond Parkinson's Disease Psychosis

Acadia Looks to Expand Drug Beyond Parkinson's Disease Psychosis

Acadia Pharmaceuticals revealed late-stage clinical data this week that could support bringing its drug for psychosis to a broader group of patients. The Acadia drug... Read more ...

FDA Puts Partial Hold on Tests of Ipsen Drug Acquired in $1B Deal

FDA Puts Partial Hold on Tests of Ipsen Drug Acquired in $1B Deal

Two clinical trials testing an Ipsen drug in rare connective tissue disorders have been placed on partial hold after safety concerns about chronic dosing of the compound... Read more ...

Bio Roundup: Biogen at CTAD, Sage's Stumble, Astellas's $3B Offer & More

Bio Roundup: Biogen at CTAD, Sage's Stumble, Astellas's $3B Offer & More

It's been a roller-coaster year for those hoping for new drugs to treat Alzheimer's disease, a leading cause of death with rising treatment costs and no clear answer yet as to... Read more ...

A Powerhouse of Cancer Research: A View from Florida

A Powerhouse of Cancer Research: A View from Florida

Nearly everyone has been affected by cancer , either through a personal diagnosis or that of a loved one. In the U.S., 1.7 million people are diagnosed each year, and over 15... Read more ...

Biogen Points to Enrollment and Dosing to Explain Alzheimer's Results

Biogen Points to Enrollment and Dosing to Explain Alzheimer's Results

Biogen revealed detailed results from its Alzheimer's trial to a jam-packed room of eager conference attendees this week-and while some described it as a major advance in the... Read more ...

Family with Two Rare Syndromes Reveals Immunity Glitch

Family with Two Rare Syndromes Reveals Immunity Glitch

Members of a three-generation family in France who suffer from widespread infections and fragile skin, joints, bones, and blood vessels share an underlying and unexpected... Read more ...

Application of A KNN‐based Similarity Method to Biopharmaceutical Manufacturing

Abstract Machine learning based similarity analysis is commonly found in many artificial intelligence applications like the one utilized in e‐commerce and digital marketing. In... Read more ...

Scientists detail how chromosomes reorganize after cell division

Researchers have discovered key mechanisms and structural details of a fundamental biological process - how a cell nucleus and its chromosomal material reorganizes itself after... Read more ...