17Β-ESTRADIOL AFFECTS THE INNATE IMMUNE RESPONSE IN COMMON CARP

Abstract Inflammation is the evolutionary conserved immune response to harmful stimuli such as pathogens or damaged cells. This multistep...

THE VOLTAGE-GATED T-TYPE CA 2+ CHANNEL IS KEY TO THE SPERM MOTILITY OF ATLANTIC SALMON

Abstract Ca 2+ is a key element in the sperm activation process of Salmo salar. However, the molecular mechanisms by which this ion...

 
 
 

IRON DYSHOMEOSTASIS PARTICIPATED IN RAT HIPPOCAMPUS TOXICITY CAUSED BY ALUMINUM CHLORIDE

Abstract Aluminum alters iron regulatory factors content and leads to the changes in iron-related proteins causing iron accumulation....

COMPARATIVE ITRAQ PROTEOMICS REVEALS MULTIPLE EFFECTS OF SELENIUM YEAST ON DAIRY COWS IN PARTURITION

Abstract The effects of prepartum dietary supplementation with selenium yeast on low abundant plasma proteins in postpartum dairy cows...

 
 
 

SFPQ AND TAU: CRITICAL FACTORS CONTRIBUTING TO RAPID PROGRESSION OF ALZHEIMER'S DISEASE

Abstract Dysfunctional RNA-binding proteins have been implicated in several neurodegenerative disorders. Recently, this paradigm of...

RUNX1-ACTIVATED UPREGULATION OF LNCRNA RNCR3 PROMOTES CELL PROLIFERATION, INVASION, AND SUPPRESSES APOPTOSIS IN COLORECTAL CANCER VIA MIR-1301-3P/AKT1 AXIS IN VITRO AND IN VIVO

Abstract Purpose Long non-coding RNAs have participated in progression of colorectal cancer. This study aims to study the role of RUNX1/RNCR3/miR-1301-3p/AKT1...

 
 
 

CURRENT UPDATES ON THE ROLE OF REACTIVE OXYGEN SPECIES IN BLADDER CANCER PATHOGENESIS AND THERAPEUTICS

Abstract Bladder cancer is the fourth most common urological malignancy in the world, it has become the costliest cancer to manage...

EXPRESSION-BASED, CONSISTENT BIOMARKERS FOR PROGNOSIS AND DIAGNOSIS IN LUNG CANCER

Abstract Overview Lung cancer is one of the deadliest cancers in the world. Its histological classification depends on early diagnosis...

 
 
 

SMN1 GENE COPY NUMBER ANALYSIS FOR SPINAL MUSCULAR ATROPHY IN A TURKISH COHORT BY CODE-SEQ TECHNOLOGY, AN INTEGRATED SOLUTION FOR DETECTION OF SMN1 AND SMN2 COPY NUMBERS AND THE “2+0” GENOTYPE

Abstract Introduction Spinal muscular atrophy is one of the common autosomal recessive disorders with global heterozygous carrier frequency...

OVEREXPRESSION MIR-486-3P PROMOTED BY ALLICIN ENHANCES TEMOZOLOMIDE SENSITIVITY IN GLIOBLASTOMA VIA TARGETING MGMT

Abstract Glioblastoma is the most common primary tumor of the central nervous system that develops chemotherapy resistance. Previous...

 
 
 

CRISPR-CAS9 GENOME EDITING TOOL FOR THE PRODUCTION OF INDUSTRIAL BIOPHARMACEUTICALS

Abstract A broad range of cell lines with characteristic features are used as bio-factories to produce recombinant proteins for basic...

A NEW APPROACH FOR PREDICTION OF THE WEAR LOSS OF PTA SURFACE COATINGS USING ARTIFICIAL NEURAL NETWORK AND BASIC, KERNEL-BASED, AND WEIGHTED EXTREME LEARNING MACHINE

Abstract Wear tests are essential in the design of parts intended to work in environments that subject a part to high wear. Wear tests...

 
 
 

TRIBOLOGICAL PERFORMANCE AND MICROSTRUCTURAL EVOLUTION OF Α-BRASS ALLOYS AS A FUNCTION OF ZINC CONCENTRATION

Abstract Tailoring a material's properties for low friction and little wear in a strategic fashion is a long-standing goal of materials...

INFLUENCE OF WHITE ETCHING LAYER ON ROLLING CONTACT BEHAVIOR AT WHEEL-RAIL INTERFACE

Abstract The existence of narrow and brittle white etching layers on the rail surface is often linked with the formation of rail defects...

 
 
 

FUNCTIONAL ANALYSIS OF CALCIUM-SENSING RECEPTOR VARIANTS IDENTIFIED IN FAMILIES PROVISIONALLY DIAGNOSED WITH FAMILIAL HYPOCALCIURIC HYPERCALCAEMIA

Abstract Identification of variants in the calcium-sensing receptor gene is an important means of distinguishing between familial hypocalciuric...

NAD + PRECURSOR INCREASES AEROBIC PERFORMANCE IN MICE

Abstract Purpose Nicotinamide riboside acts as a potent NAD + precursor and improves mitochondrial oxidative capacity and mitochondrial...

 
 
 

DE NOVO TRANSCRIPTOME OF THE WHOLE-BODY OF THE GASTROPOD MOLLUSK PHILOMYCUS BILINEATUS, A PEST WITH MEDICAL POTENTIAL IN CHINA

Abstract Philomycus bilineatus is a highly common gastropod mollusk pest in China and is also utilized to treat infectious diseases....

ESTABLISHMENT AND EVALUATION OF A METHOD FOR EFFICIENT SCREENING OF CLOSTRIDIUM BUTYRICUM

Abstract At present, the traditional methods for the screening of Clostridium butyricum are not sufficiently selective and efficient....

 
 
 

THE CROSS-SECTIONAL STUDY OF TOXOPLASMA GONDII SEROPREVALENCE IN SELECTED GROUPS OF POPULATION IN SLOVAKIA

Abstract Toxoplasma gondii is an obligate intracellular protozoan parasite with domestic or free-living members of family Felidae known...

INSUFFICIENT REPEATABILITY AND REPRODUCIBILITY OF MALDI-TOF MS-BASED IDENTIFICATION OF MRSA

Abstract Rapid identification of methicillin-resistant Staphylococcus aureus is essential for proper initial antibiotic therapy and...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

How COVID-19 Arose and Amplified Along the Meat Supply Chain

How COVID-19 Arose and Amplified Along the Meat Supply Chain

Early in this unforgettable year, a wet market in Wuhan, China, emerged as a possible step along the way, if not the place of origin, of the outbreak that would seed the... Read more ...

Global Methane Emissions Soaring, But How Much Was Due to Wetlands?

Global Methane Emissions Soaring, But How Much Was Due to Wetlands?

Infographic published with permission from the authors of “Increasing anthropogenic methane emissions arise equally from agricultural and fossil fuel sources.” (Credit: Jackson... Read more ...

Computer System Assurance: A Paradigm Shift Away from Compliance to Quality

Computer System Assurance: A Paradigm Shift Away from Compliance to Quality

Our Professional Services Written by: Gary E. Ritchie, MS, Senior Validation Engineer Consultant, PSC Biotech Corporation The FDA will release the draft guidance on Computer... Read more ...

With FDA Nod, NS Pharma Duchenne Drug Becomes Sarepta Competitor

With FDA Nod, NS Pharma Duchenne Drug Becomes Sarepta Competitor

Duchenne muscular dystrophy patients whose disease is characterized by a particular genetic mutation now have a new treatment option following the FDA's Wednesday approval of a... Read more ...

Perceptive Advisors' LianBio Inks Deals With BridgeBio, MyoKardia

Perceptive Advisors' LianBio Inks Deals With BridgeBio, MyoKardia

Two California biotechs have teamed up with LianBio, a new company launched earlier this week by hedge fund Perceptive Advisors, as part of deals that expand their reach into... Read more ...

F2G Lands $60M for a New Tack on Taking Out Rare Fungal Infections

F2G Lands $60M for a New Tack on Taking Out Rare Fungal Infections

Fungal infections might not immediately come to mind as rare diseases, but growing resistance to older drugs means that patients who develop these infections have limited... Read more ...

Calliditas gets controlling stake, option to buy out Genkyotex and its...

Calliditas gets controlling stake, option to buy out Genkyotex and its failed PBC drug badams Fri, 08/14/2020 - 05:07 Read more ...

17β-Estradiol affects the innate immune response in common carp

Abstract Inflammation is the evolutionary conserved immune response to harmful stimuli such as pathogens or damaged cells. This multistep process acts by removing injurious... Read more ...

Chutes & Ladders-WuXi taps veteran operations head Dong to lead new vaccines...

Chutes & Ladders-WuXi taps veteran operations head Dong to lead new vaccines unit kblankenship Fri, 08/14/2020 - 08:23 Read more ...

Team discovers a new role for a well-known molecule as a plant hormone

Researchers at the University of Maryland have discovered an entirely new role for a well-known plant molecule called ACC, providing the first clear example of ACC acting on... Read more ...