RANA-SEQ: INTERACTIVE RNA-SEQ ANALYSIS FROM FASTQ FILES TO FUNCTIONAL ANALYSIS

AbstractSummaryRaNA-Seq is a cloud platform for the rapid analysis and visualization of RNA-Seq data. It performs a full analysis in...

GTDB-TK: A TOOLKIT TO CLASSIFY GENOMES WITH THE GENOME TAXONOMY DATABASE

AbstractSummaryThe GTDB Toolkit provides objective taxonomic assignments for bacterial and archaeal genomes based on the Genome Taxonomy...

 
 
 

CROSS-LINGUAL SEMANTIC ANNOTATION OF BIOMEDICAL LITERATURE: EXPERIMENTS IN SPANISH AND ENGLISH

AbstractMotivationBiomedical literature is one of the most relevant sources of information for knowledge mining in the field of Bioinformatics....

NCUTYX: A PACKAGE FOR CLUSTERING ANALYSIS OF MULTILAYER OMICS DATA

AbstractSummaryMultilayer omics profiling has become a major venue for understanding complex diseases. We develop NCutYX, an R package...

 
 
 

PRIORS FOR GENOTYPING POLYPLOIDS

AbstractMotivationEmpirical Bayes techniques to genotype polyploid organisms usually either assume technical artifacts are known a...

ESTIMATING CHAIN LENGTHS FOR TIME DELAYS IN DYNAMICAL SYSTEMS USING PROFILE LIKELIHOOD

AbstractMotivationApparent time delays in partly observed, biochemical reaction networks can be modeled by lumping a more complex reaction...

 
 
 

MILES: A JAVA TOOL TO EXTRACT NODE-SPECIFIC ENRICHED SUBGRAPHS IN BIOMOLECULAR NETWORKS

AbstractSummaryThe growing availability of biomolecular networks has led to a need for analysis methods that are able to extract biologically...

DIGESTIFLOW: FROM BCL TO FASTQ WITH EASE

AbstractSummaryManagement raw sequencing data and its preprocessing (conversion into sequences and demultiplexing) remains a challenging...

 
 
 

SOMATIC SELECTION DISTINGUISHES ONCOGENES AND TUMOR SUPPRESSOR GENES

AbstractMotivationFunctions of cancer driver genes vary substantially across tissues and organs. Distinguishing passenger genes , oncogenes...

DIFFERENTIATING ISOFORM FUNCTIONS WITH COLLABORATIVE MATRIX FACTORIZATION

AbstractMotivationIsoforms are alternatively spliced mRNAs of genes. They can be translated into different functional proteoforms,...

 
 
 

MINING SINGLE-CELL TIME-SERIES DATASETS WITH TIME COURSE INSPECTOR

AbstractSummaryThanks to recent advances in live cell imaging of biosensors, microscopy experiments can generate thousands of single-cell...

ON THE INCONSISTENT TREATMENT OF GENE-PROTEIN-REACTION RULES IN CONTEXT-SPECIFIC METABOLIC MODELS

Supplementary informationSupplementary dataSupplementary data are available at Bioinformatics online.

 
 
 

LEARNING COMPLEX SUBCELLULAR DISTRIBUTION PATTERNS OF PROTEINS VIA ANALYSIS OF IMMUNOHISTOCHEMISTRY IMAGES

AbstractMotivationSystematic and comprehensive analysis of protein subcellular location as a critical part of proteomics has been studied...

PROAFFIMUSEQ: SEQUENCE-BASED METHOD TO PREDICT THE BINDING FREE ENERGY CHANGE OF PROTEIN-PROTEIN COMPLEXES UPON MUTATION USING FUNCTIONAL CLASSIFICATION

AbstractMotivationProtein-protein interactions are essential for the cell and mediate various functions. However, mutations can disrupt...

 
 
 

DIVERSITY OF RHODOPSINS IN CULTIVATED BACTERIA OF THE FAMILY GEODERMATOPHILACEAE ASSOCIATED WITH NON-AQUATIC ENVIRONMENTS

AbstractMotivationA small amount of research is focused on investigation of rhodopsins in cultivated bacteria isolated from non-aquatic...

EPIDISH WEB SERVER: EPIGENETIC DISSECTION OF INTRA-SAMPLE-HETEROGENEITY WITH ONLINE GUI

AbstractSummaryIt is well recognized that cell-type heterogeneity hampers the interpretation of Epigenome-Wide Association Studies....

 
 
 

THE CYTOSCAPE BIOGATEWAY APP: EXPLORATIVE NETWORK BUILDING FROM THE BIOGATEWAY TRIPLE STORE

AbstractSummaryThe BioGateway App is a Cytoscape plugin designed to provide easy query access to the BioGateway RDF triple store, which...

DRAWGLYCAN-SNFG & GPANNOTATE: RENDERING GLYCANS AND ANNOTATING GLYCOPEPTIDE MASS SPECTRA

AbstractSummaryThis manuscript describes an open-source program, DrawGlycan-SNFG , that accepts IUPAC (International Union of Pure...

 
 
 

ESTIMATION OF EOSINOPHIL CELLS IN CORD BLOOD WITH REFERENCES BASED ON BLOOD IN ADULTS VIA BAYESIAN MEASUREMENT ERROR MODELING

AbstractMotivationEosinophils are phagocytic white blood cells with a variety of roles in the immune system. In situations where actual...

MODEL SELECTION FOR METABOLOMICS: PREDICTING DIAGNOSIS OF CORONARY ARTERY DISEASE USING AUTOMATED MACHINE LEARNING

AbstractMotivationSelecting the optimal machine learning model for a given dataset is often challenging. Automated ML has emerged as...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

IAmScience Clayton Kranawetter

IAmScience Clayton Kranawetter

By Mariah Cox | Bond LSC Taking things apart to figure out how they function was a huge part of Clayton Kranawetter's childhood. From dismantling his parents' old computer to... Read more ...

Cellular “Cleaners” More Active in Quiet Brains

Cellular “Cleaners” More Active in Quiet Brains

Like a robot vacuum for your brain, immune cells called microglia survey around and hoover up the neuro-equivalent of crumbs and dirt. But for the first time Mayo researchers... Read more ...

ResTORbio's Respiratory Drug Flunks Phase 3 Test, Shattering Shares

ResTORbio's Respiratory Drug Flunks Phase 3 Test, Shattering Shares

A resTORbio respiratory drug has failed a late-stage test, and the company is stopping further development of the compound for lung infections in elderly patients. In the first... Read more ...

Biotech Roundup: Gottlieb v. Juul, Solid Slumps, Avidity Gets $100M & More

Biotech Roundup: Gottlieb v. Juul, Solid Slumps, Avidity Gets $100M & More

Lung injuries connected to the use of electronic cigarettes have topped 2,000 and killed 40 people, according to the Centers for Disease Control and Prevention. It's still... Read more ...

Daré to Add Microchip-Based Birth Control to Women's Health Portfolio

Daré to Add Microchip-Based Birth Control to Women's Health Portfolio

The list of activities our smartphones can control grows daily. Transfer money? It's simple. Order groceries? That, too. Turn off the bedroom lights? Check. How about... Read more ...

Webinar Summary: Need accurate isoform-level characterization? Iso-Seq is...

Webinar Summary: Need accurate isoform-level characterization? Iso-Seq is the answer

Traditional RNA-Seq is done by fragmenting cDNA, and then sequencing the fragmented reads with paired-end sequencing. The problem comes when trying to identify the full-length... Read more ...

Could the Lifesaving Promises of Golden Rice FINALLY be Realized?

Could the Lifesaving Promises of Golden Rice FINALLY be Realized?

On this page we usually tout the newest examples of biotechnology innovation: jet fuels made from algae ; gene edited bananas that resist disease; soil microbes that reduce the... Read more ...

Identification of urban particulate matter-induced disruption of human...

Exposure to air particulate matter is associated with various diseases in the human respiratory system. To date, most in vitro studies showing cellular responses to PM have... Read more ...

SEQdata-BEACON: a comprehensive database of sequencing performance and...

The sequencing platform BGISEQ-500 is based on DNBSEQ technology and provides high throughput with low costs. This sequencer has been widely used in various areas of scientific... Read more ...

Success tips from women in science, for girls who want to go into science

Learning from mentors, taking chances and showing passion go a long way... Read more ...