SECURE MULTIPARTY COMPUTATION FOR PRIVACY-PRESERVING DRUG DISCOVERY

AbstractMotivationQuantitative structure-activity relationship and drug-target interaction prediction are both commonly used in drug...

CURATION AND ANNOTATION OF PLANARIAN GENE EXPRESSION PATTERNS WITH SEGMENTED REFERENCE MORPHOLOGIES

AbstractMotivationMorphological and genetic spatial data from functional experiments based on genetic, surgical, and pharmacological...

 
 
 

THE ELIXIR CORE DATA RESOURCES: FUNDAMENTAL INFRASTRUCTURE FOR THE LIFE SCIENCES

AbstractMotivationLife science research in academia, industry, agriculture, and the health sector depends critically on free and open...

TARGETED REALIGNMENT OF LC-MS PROFILES BY NEIGHBOR-WISE COMPOUND-SPECIFIC GRAPHICAL TIME WARPING WITH MISALIGNMENT DETECTION

AbstractMotivationLiquid chromatography - mass spectrometry is a standard method for proteomics and metabolomics analysis of biological...

 
 
 

INFERENCE OF GENE REGULATORY NETWORKS BASED ON NONLINEAR ORDINARY DIFFERENTIAL EQUATIONS

AbstractMotivationGene regulatory networks capture the regulatory interactions between genes, resulting from the fundamental biological...

BMDX: A GRAPHICAL SHINY APPLICATION TO PERFORM BENCHMARK DOSE ANALYSIS FOR TRANSCRIPTOMICS DATA

AbstractMotivationThe analysis of dose-dependent effects on the gene expression is gaining attention in the filed of toxicogenomics....

 
 
 

3D-CELL-ANNOTATOR: AN OPEN-SOURCE ACTIVE SURFACE TOOL FOR SINGLE CELL SEGMENTATION IN 3D MICROSCOPY IMAGES

AbstractSummarySegmentation of single cells in microscopy images is one of the major challenges in computational biology. It is the...

SIMULATING TREES WITH MILLIONS OF SPECIES

AbstractMotivationThe birth-death model constitutes the theoretical backbone of most phylogenetic tools for reconstructing speciation/extinction...

 
 
 

RXNBLAST: MOLECULAR SCAFFOLD AND REACTIVE CHEMICAL ENVIRONMENT FEATURE EXTRACTOR FOR BIOCHEMICAL REACTIONS

AbstractMotivationMolecular scaffolds are useful in medicinal chemistry to describe, discuss, and visualize series of chemical compounds,...

VISUALIZATION OF CIRCULAR RNAS AND THEIR INTERNAL SPLICING EVENTS FROM TRANSCRIPTOMIC DATA

AbstractSummaryCircular RNAs are proved to have unique compositions and splicing events distinct from canonical mRNAs. However, there...

 
 
 

THE OPEN TARGETS POST-GWAS ANALYSIS PIPELINE

AbstractMotivationGenome-wide association studies are a powerful method to detect even weak associations between variants and phenotypes,...

SINGLE-SAMPLE LANDSCAPE ENTROPY REVEALS THE IMMINENT PHASE TRANSITION DURING DISEASE PROGRESSION

Bioinformatics (2009) doi:10.1093/bioinformatics/btz758

 
 
 

PISA-SPARKY: AN INTERACTIVE SPARKY PLUGIN TO ANALYZE ORIENTED SOLID-STATE NMR SPECTRA OF HELICAL MEMBRANE PROTEINS

AbstractMotivationTwo-dimensional separated local field solid-state NMR experiments of membrane proteins aligned in lipid bilayers...

ALPSNMR: AN R PACKAGE FOR SIGNAL PROCESSING OF FULLY UNTARGETED NMR-BASED METABOLOMICS

AbstractResultsNMR-based metabolomics is widely used to obtain metabolic fingerprints of biological systems. While targeted workflows...

 
 
 

FILTAR: USING RNA-SEQ DATA TO IMPROVE MICRORNA TARGET PREDICTION ACCURACY IN ANIMALS

AbstractMotivationmicroRNA target prediction algorithms do not generally consider biological context and therefore generic target prediction...

MDEHT: A MULTIVARIATE APPROACH FOR DETECTING DIFFERENTIAL EXPRESSION OF MICRORNA ISOFORM DATA IN RNA SEQUENCING STUDIES

AbstractMotivationMiRNA isoforms are produced from the same arm as the archetype miRNA with a few nucleotides different at 5 and/or...

 
 
 

BALAS: FAST, INTERACTIVE AND ACCESSIBLE COMPUTATIONAL ALANINE-SCANNING USING BUDEALASCAN

AbstractMotivationIn experimental protein engineering, alanine-scanning mutagenesis involves the replacement of selected residues with...

CROP: CORRELATION-BASED REDUCTION OF FEATURE MULTIPLICITIES IN UNTARGETED METABOLOMIC DATA

AbstractSummaryUntargeted liquid chromatography-high-resolution mass spectrometry analysis produces a large number of features which...

 
 
 

NEAREST-NEIGHBOR PROJECTED-DISTANCE REGRESSION FOR DETECTING NETWORK INTERACTIONS WITH ADJUSTMENTS FOR MULTIPLE TESTS AND CONFOUNDING

AbstractMachine learning feature selection methods are needed to detect complex interaction-network effects in complicated modeling...

THE PROTEIN IMAGER: A FULL-FEATURED ONLINE MOLECULAR VIEWER INTERFACE WITH SERVER-SIDE HQ-RENDERING CAPABILITIES

AbstractSummaryMolecular viewers' long learning curve is hindering researchers in approaching the field of structural biology for the...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Interfacial molecular interactions of cellobiohydrolase Cel7A and its...

Molecular-scale mechanisms of the enzymatic breakdown of cellulosic biomass into fermentable sugars are still poorly understood, with a need for independent measurements of... Read more ...

Brassinosteroid overproduction improves lignocellulose quantity and quality...

As a leading biomass feedstock, poplar plants provide enormous lignocellulose resource convertible for biofuels and bio-chemicals. However, lignocellulose recalcitrance... Read more ...

US biofuel production and policy: implications for land use changes in...

It has been argued that the US biofuel policy is responsible for the land use changes in Malaysia and Indonesia. In this paper, following a short literature review that... Read more ...

Programmable nests for cells

Using DNA, smallest silica particles, and carbon nanotubes, researchers developed novel programmable materials. These nanocomposites can be tailored to various applications and... Read more ...

AveXis Inc.: Research Associate III

AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...

Mirati Therapeutics: Student Assistant

Mirati Therapeutics: Mirati Therapeutics is a targeted oncology company developing an advanced pipeline of breakthrough medicines for precisely defined patient populations San... Read more ...

Inhibition of lignification of Zizania latifolia with radio frequency...

Zizania latifolia is easily lignified after harvesting, leading to the degradation of food quality and commercial value. Thus, this study evaluated the effect of radio... Read more ...

Performance difference of graph-based and alignment-based hybrid error...

The error-prone third-generation sequencing long reads can be corrected by the high-quality second-generation sequencing short reads, which is referred to as hybrid error... Read more ...

CHROMATIX: computing the functional landscape of many-body chromatin...

Chromatin interactions are important for gene regulation and cellular specialization. Emerging evidence suggests many-body spatial interactions play important roles in... Read more ...

Bachem: Validation Engineer II, QA

Bachem: Your Responsibilities The Validation Engineer II fulfills a critical role in GMP operations. This individual must plan and execute validation studies, Vista, CA, US ... Read more ...