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BMC Biotechnology

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CHARACTERIZATION AND GENOMIC ANALYSIS OF A DIESEL-DEGRADING BACTERIUM, ACINETOBACTER CALCOACETICUS CA16, ISOLATED FROM CANADIAN SOIL

With the high demand for diesel across the world, environmental decontamination from its improper usage, storage and accidental spills...

ATTENUATION OF INTESTINAL INFLAMMATION IN IL-10 DEFICIENT MICE BY A PLASMID CARRYING LACTOCOCCUS LACTIS STRAIN

Inflammatory bowel diseases are intestinal disorders characterized by inflammation in the gastrointestinal tract and to date, no efficient...

 
 
 

ONE-STEP HEATING STRATEGY FOR EFFICIENT SOLUBILIZATION OF RECOMBINANT SPIDER SILK PROTEIN FROM INCLUSION BODIES

Spider silk is a proteinaceous fiber with remarkable mechanical properties spun from spider silk proteins. Engineering spidroins have...

FUNCTIONAL EXPRESSION OF A NOVEL METHANOL-STABLE ESTERASE FROM GEOBACILLUS SUBTERRANEUS DSM13552 FOR BIOCATALYTIC SYNTHESIS OF CINNAMYL ACETATE IN A SOLVENT-FREE SYSTEM

Esterases are widely distributed in nature and have important applications in medical, industrial and physiological. Recently, the...

 
 
 

EFFICIENT CRISPR/CAS9 GENOME EDITING IN A SALMONID FISH CELL LINE USING A LENTIVIRUS DELIVERY SYSTEM

Genome editing is transforming bioscience research, but its application to non-model organisms, such as farmed animal species, requires...

AN IMPROVED QUANTITATIVE REAL-TIME POLYMERASE CHAIN REACTION TECHNOLOGY FOR HELICOBACTER PYLORI DETECTION IN STOMACH TISSUE AND ITS APPLICATION VALUE IN CLINICAL PRECISION TESTING

Helicobacter pylori infection is a serious human health threat. The empiric H. pylori treatment paradigm guided by traditional testing...

 
 
 

LOOP-MEDIATED ISOTHERMAL AMPLIFICATION REACTION AS VIABLE PCR SUBSTITUTE FOR DIAGNOSTIC APPLICATIONS: A COMPARATIVE ANALYSIS STUDY OF LAMP, CONVENTIONAL PCR, NESTED PCR AND REAL-TIME PCR BASED ON ENTAMOEBA HISTOLYTICA DNA DERIVED FROM FAECAL SAMPLE

This study reports the analytical sensitivity and specificity of a Loop-mediated isothermal amplification and compares its amplification...

EVALUATION OF HYDRA HALT-1 AS A TOXIN MOIETY FOR RECOMBINANT IMMUNOTOXIN

Immunotoxin is a hybrid protein consisting of a toxin moiety that is linked to a targeting moiety for the purpose of specific elimination...

 
 
 

INTERFERENCE CHROMATOGRAPHY: A NOVEL APPROACH TO OPTIMIZING CHROMATOGRAPHIC SELECTIVITY AND SEPARATION PERFORMANCE FOR VIRUS PURIFICATION

Oncolytic viruses are playing an increasingly important role in cancer immunotherapy applications. Given the preclinical and clinical...

COLORECTAL CYSTS AS A VALIDATING TOOL FOR CAR THERAPY

Treatment of cancers has largely benefited from the development of immunotherapy. In particular, Chimeric Antigen Receptor redirected...

 
 
 

IN VITRO BIOSYNTHESIS OF AG, AU AND TE-CONTAINING NANOSTRUCTURES BY EXIGUOBACTERIUM CELL-FREE EXTRACTS

The bacterial genus Exiguobacterium includes several species that inhabit environments with a wide range of temperature, salinity,...

RECOMBINANT PAL/PILE/FLAA DNA VACCINE PROVIDES PROTECTIVE IMMUNITY AGAINST LEGIONELLA PNEUMOPHILA IN BALB/C MICE

Legionella pneumophila , a Gram-negative small microorganism, causes hospital-acquired pneumonia especially in immunocompromised patients....

 
 
 

GENERATION OF TRANSGENE-FREE PDS MUTANTS IN POTATO BY AGROBACTERIUM-MEDIATED TRANSFORMATION

Gene editing using the CRISPR/Cas9 system has become a routinely applied method in several plant species. The most convenient gene...

GOLDENBAC: A SIMPLE, HIGHLY EFFICIENT, AND WIDELY APPLICABLE SYSTEM FOR CONSTRUCTION OF MULTI-GENE EXPRESSION VECTORS FOR USE WITH THE BACULOVIRUS EXPRESSION VECTOR SYSTEM

Recombinant protein production and purification of large protein complexes in eukaryotes requires efficient methods to generate multi-gene...

 
 
 

SCREENING OF FIVE MARINE-DERIVED FUNGAL STRAINS FOR THEIR POTENTIAL TO PRODUCE OXIDASES WITH LACCASE ACTIVITIES SUITABLE FOR BIOTECHNOLOGICAL APPLICATIONS

Environmental pollution is one of the major problems that the world is facing today. Several approaches have been taken, from physical...

RETRACTION NOTE: DNA METHYLOME PROFILING AT SINGLE-BASE RESOLUTION THROUGH BISULFITE SEQUENCING OF 5MC-IMMUNOPRECIPITATED DNA

An amendment to this paper has been published and can be accessed via the original article.

 
 
 

TRANSLATIONAL REGULATION OF PERIPLASMIC FOLDING ASSISTANTS AND PROTEASES AS A VALUABLE STRATEGY TO IMPROVE PRODUCTION OF TRANSLOCATED RECOMBINANT PROTEINS IN ESCHERICHIA COLI

Advantages of translocation of recombinant proteins to the periplasm in Escherichia coli include simplified downstream processing,...

PROCESS OPTIMIZATION AND EFFECT OF THERMAL, ALKALINE, H2O2 OXIDATION AND COMBINATION PRETREATMENT OF SEWAGE SLUDGE ON SOLUBILIZATION AND ANAEROBIC DIGESTION

This study investigated the feasibility of enhancing anaerobic digestion of sewage sludge with triple, dual, and individual pretreatment...

 
 
 

UTILIZATION OF EGG-LAYING HENS FOR PRODUCTION OF INGREDIENTS FOR HUMAN CONSUMPTION AND ANIMAL FEED

In Norway, 3 million discarded egg-laying hens are destructed annually, which equals 1500 tons pure hen meat. Due to the slaughter...

PHYTOREMEDIATION EFFECT OF MEDICAGO SATIVA COLONIZED BY PIRIFORMOSPORA INDICA IN THE PHENANTHRENE AND CADMIUM CO-CONTAMINATED SOIL

The coexistence of polycyclic aromatic hydrocarbons and heavy metals has deleterious effects on environmental quality. Few reports...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Advisory Body Backs MesoBlast Therapy for Transplant Complication

Advisory Body Backs MesoBlast Therapy for Transplant Complication

An FDA advisory committee Thursday voted 9-1 to recommend that the agency approve a stem cell therapy developed by MesoBlast as a treatment for acute graft-versus-host disease... Read more ...

CureVac's IPO Hauls In $213M as Key mRNA COVID-19 Vaccine Test Nears

CureVac's IPO Hauls In $213M as Key mRNA COVID-19 Vaccine Test Nears

CureVac is playing catch-up to its messenger RNA peers in the race to develop a COVID-19 vaccine, but the company contends its technology could offer dosing advantages, and it... Read more ...

Bio Roundup: Seres Soars, MesoBlast Vote, Duchenne Decision & More

Bio Roundup: Seres Soars, MesoBlast Vote, Duchenne Decision & More

The road of drug development is rife with detours and disappointments but Seres Therapeutics showed this week that course corrections can work. Four years after its microbiome... Read more ...

How COVID-19 Arose and Amplified Along the Meat Supply Chain

How COVID-19 Arose and Amplified Along the Meat Supply Chain

Early in this unforgettable year, a wet market in Wuhan, China, emerged as a possible step along the way, if not the place of origin, of the outbreak that would seed the... Read more ...

Global Methane Emissions Soaring, But How Much Was Due to Wetlands?

Global Methane Emissions Soaring, But How Much Was Due to Wetlands?

Infographic published with permission from the authors of “Increasing anthropogenic methane emissions arise equally from agricultural and fossil fuel sources.” (Credit: Jackson... Read more ...

Computer System Assurance: A Paradigm Shift Away from Compliance to Quality

Computer System Assurance: A Paradigm Shift Away from Compliance to Quality

Our Professional Services Written by: Gary E. Ritchie, MS, Senior Validation Engineer Consultant, PSC Biotech Corporation The FDA will release the draft guidance on Computer... Read more ...

Regulation of tumor necrosis superfamily molecules, BAFF and APRIL, in...

Abstract Tumor necrosis factor superfamily molecules are important inflammatory cytokines, which are involved in diverse immunological functions such as B-cell regulation and... Read more ...

Changes of water, sediment, and intestinal bacterial communities in Penaeus...

Abstract More and more studies have revealed a close relationship between gut microbial community and human health. However, the mechanism why changes in gut microflora... Read more ...

ACS BIOL Broadcast Questions and Discussion Link

This Link will be open between 11:30 AM - 12:45 PM for the AM Broadcast Session and 2:30 - 3:45 PM for the PM Broadcast Session each day. These times are Pacific Time. Read more ...

SQMtools: automated processing and visual analysis of 'omics data with R and...

The dramatic decrease in sequencing costs over the last decade has boosted the adoption of high-throughput sequencing applications as a standard tool for the analysis of... Read more ...