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BMC Bioinformatics

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TRACKING INTRATUMORAL HETEROGENEITY IN GLIOBLASTOMA VIA REGULARIZED CLASSIFICATION OF SINGLE-CELL RNA-SEQ DATA

Understanding cellular and molecular heterogeneity in glioblastoma , the most common and aggressive primary brain malignancy, is a...

RPI-SE: A STACKING ENSEMBLE LEARNING FRAMEWORK FOR NCRNA-PROTEIN INTERACTIONS PREDICTION USING SEQUENCE INFORMATION

The interactions between non-coding RNAs and proteins play an essential role in many biological processes. Several high-throughput...

 
 
 

GRAPH REGULARIZED L2,1-NONNEGATIVE MATRIX FACTORIZATION FOR MIRNA-DISEASE ASSOCIATION PREDICTION

The aberrant expression of microRNAs is closely connected to the occurrence and development of a great deal of human diseases. To study...

IPCO: INFERENCE OF PATHWAYS FROM CO-VARIANCE ANALYSIS

Key aspects of microbiome research are the accurate identification of taxa and the profiling of their functionality. Amplicon profiling...

 
 
 

ANALYSES ON CLUSTERING OF THE CONSERVED RESIDUES AT PROTEIN-RNA INTERFACES AND ITS APPLICATION IN BINDING SITE IDENTIFICATION

The maintenance of protein structural stability requires the cooperativity among spatially neighboring residues. Previous studies have...

SPECS: A NON-PARAMETRIC METHOD TO IDENTIFY TISSUE-SPECIFIC MOLECULAR FEATURES FOR UNBALANCED SAMPLE GROUPS

To understand biology and differences among various tissues or cell types, one typically searches for molecular features that display...

 
 
 

ISEQQC: A TOOL FOR EXPRESSION-BASED QUALITY CONTROL IN RNA SEQUENCING

Quality Control in any high-throughput sequencing technology is a critical step, which if overlooked can compromise an experiment and...

GSMPLOT: A WEB SERVER TO VISUALIZE EPIGENOME DATA IN NCBI

Epigenetic regulation is essential in regulating gene expression across a variety of biological processes. Many high-throughput sequencing...

 
 
 

USHR: UNDERSTANDING SUPPRESSION OF HIV IN R

HIV/AIDS is responsible for the deaths of one million people every year. Although mathematical modeling has provided many insights...

DTRANNER: BIOMEDICAL NAMED ENTITY RECOGNITION WITH DEEP LEARNING-BASED LABEL-LABEL TRANSITION MODEL

Biomedical named-entity recognition is widely modeled with conditional random fields by regarding it as a sequence labeling problem....

 
 
 

GARS: GENETIC ALGORITHM FOR THE IDENTIFICATION OF A ROBUST SUBSET OF FEATURES IN HIGH-DIMENSIONAL DATASETS

Feature selection is a crucial step in machine learning analysis. Currently, many feature selection approaches do not ensure satisfying...

CORRECTION TO: SLR: A SCAFFOLDING ALGORITHM BASED ON LONG READS AND CONTIG CLASSIFICATION

Following publication of the original article , the author reported that there is an error in the original article.

 
 
 

DEEP LEARNING IMPROVES THE ABILITY OF SGRNA OFF-TARGET PROPENSITY PREDICTION

CRISPR/Cas9 system, as the third-generation genome editing technology, has been widely applied in target gene repair and gene expression...

PANEV: AN R PACKAGE FOR A PATHWAY-BASED NETWORK VISUALIZATION

During the last decade, with the aim to solve the challenge of post-genomic and transcriptomic data mining, a plethora of tools have...

 
 
 

BIOMEDICAL EVENT EXTRACTION WITH A NOVEL COMBINATION STRATEGY BASED ON HYBRID DEEP NEURAL NETWORKS

Biomedical event extraction is a fundamental and in-demand technology that has attracted substantial interest from many researchers....

PRIMARY ORTHOLOGS FROM LOCAL SEQUENCE CONTEXT

The evolutionary history of genes serves as a cornerstone of contemporary biology. Most conserved sequences in mammalian genomes don't...

 
 
 

DRUG-TARGET INTERACTION PREDICTION WITH TREE-ENSEMBLE LEARNING AND OUTPUT SPACE RECONSTRUCTION

Computational prediction of drug-target interactions is vital for drug discovery. The experimental identification of interactions between...

ECFS-DEA: AN ENSEMBLE CLASSIFIER-BASED FEATURE SELECTION FOR DIFFERENTIAL EXPRESSION ANALYSIS ON EXPRESSION PROFILES

Various methods for differential expression analysis have been widely used to identify features which best distinguish between different...

 
 
 

MULTI-TEMPLATE MATCHING: A VERSATILE TOOL FOR OBJECT-LOCALIZATION IN MICROSCOPY IMAGES

The localization of objects of interest is a key initial step in most image analysis workflows. For biomedical image data, classical...

GEDI: APPLYING SUFFIX ARRAYS TO INCREASE THE REPERTOIRE OF DETECTABLE SNVS IN TUMOUR GENOMES

Current popular variant calling pipelines rely on the mapping coordinates of each input read to a reference genome in order to detect...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Imara Reveals IPO Plan as Sickle Cell Drug Advances in the Clinic

Imara Reveals IPO Plan as Sickle Cell Drug Advances in the Clinic

Sickle cell disease research is seeing a flurry of activity with several companies currently testing therapies for the genetic blood disorder and one company recently receiving... Read more ...

Xcelerating Life Sciences Boston Will Explore Biopharma's Future in Digital...

Xcelerating Life Sciences Boston Will Explore Biopharma's Future in Digital Health

Join Xconomy on April 29 at Takeda Pharmaceuticals' Boston location for the next in our Xcelerating Life Sciences event series: Biopharma's Future in Digital Health. The... Read more ...

ResTORbio Pins “Strategic Alternatives” Pitch to Parkinson's Promise

ResTORbio Pins “Strategic Alternatives” Pitch to Parkinson's Promise

Three months after resTORbio's lead drug failed a pivotal test treating lung infections in the elderly , the company is now looking for someone to buy the firm or strike a deal... Read more ...

How Gene Therapy Could Cure Cocaine Addiction

How Gene Therapy Could Cure Cocaine Addiction

Cocaine is like a roller coaster in powder form. First, there is the intense rush of euphoria, excitement, and invincibility. Then, almost as quickly, there is the crash into... Read more ...

Nanoparticles From Fat May be Useful in Treating Inflammatory Diseases

Nanoparticles From Fat May be Useful in Treating Inflammatory Diseases

In a new study, a multidisciplinary Mayo Clinic team discovered that nano-sized particles produced by cells in human fat have anti-inflammatory properties in immune cells and... Read more ...

New Meds Set to Reshape US CNS and oncology Markets

New Meds Set to Reshape US CNS and oncology Markets

CNS and cancer will be biopharma battlegrounds this year according to Clarivate Analytics, which says new meds will reshape the US market. The US Food and Drug Administration... Read more ...

Quality Assurance Associate I - Catalent Pharma Solutions - San Diego, CA

Analytical laboratory, QC laboratory, Manufacturing, QA experience may be considered applicable. Your expertise, coupled with Catalent's advanced technologies...From Catalent... Read more ...

Engineer II - Bachem - Vista, CA

The company provides a full range of services to the pharma and biotech industries. Develop and train employees on utilization of maintenance schedule for new...From Bachem... Read more ...

103998 Basic Science Research Associate

PHARMACOLOGY Salary commensurate with qualifications and experienceFiling Deadline: Wed 3/4/2020... Read more ...

Research shows the way to more efficient EPO production

To many people, EPO rhymes with doping and cycling. But in fact, EPO is an important medical drug. This hormone works naturally in the body by stimulating red blood cell... Read more ...