SELECTIVE INHIBITION OF MATRIX METALLOPROTEINASE 10 WITH A SINGLE-DOMAIN ANTIBODY
Since their discovery, the matrix metalloproteinase family of proteases have been considered as therapeutic targets in numerous diseases...
MOLECULAR BASIS FOR FIBROBLAST GROWTH FACTOR 23 O -GLYCOSYLATION BY GALNAC-T3
Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0444-x Polypeptide GalNAc-transferase T3 catalyzes...
REPROGRAMMING FATTY ACYL SPECIFICITY OF LIPID KINASES VIA C1 DOMAIN ENGINEERING
Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0445-9 A chemoproteomics and protein engineering...
A FUNGAL FAMILY OF LYTIC POLYSACCHARIDE MONOOXYGENASE-LIKE COPPER PROTEINS
Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0438-8 The X325 protein family is highly similar...
REWIRING E2 ENZYMES
Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0454-8 The site-specific monoubiquitination of FANCD2...
LIPID DROPLETS CAN PROMOTE DRUG ACCUMULATION AND ACTIVATION
Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0447-7 Lasonolide A is hydrolyzed into a cytotoxic...
A LYTIC POLYSACCHARIDE MONOOXYGENASE-LIKE PROTEIN FUNCTIONS IN FUNGAL COPPER IMPORT AND MENINGITIS
Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0437-9 In the fungal pathogen Cryptococcus neoformans,...
AUTHOR CORRECTION: STRUCTURAL BASIS OF INDISULAM-MEDIATED RBM39 RECRUITMENT TO DCAF15 E3 LIGASE COMPLEX
Nature Chemical Biology, Published online: 15 January 2020; doi:10.1038/s41589-020-0471-7 Author Correction: Structural basis of indisulam-mediated...
PUBLISHER CORRECTION: AN EFFICIENT GENE KNOCK-IN STRATEGY USING 5′-MODIFIED DOUBLE-STRANDED DNA DONORS WITH SHORT HOMOLOGY ARMS
Nature Chemical Biology, Published online: 15 January 2020; doi:10.1038/s41589-020-0470-8 Publisher Correction: An efficient gene knock-in...
CHAIN ALIGNMENT OF COLLAGEN I DECIPHERED USING COMPUTATIONALLY DESIGNED HETEROTRIMERS
Nature Chemical Biology, Published online: 06 January 2020; doi:10.1038/s41589-019-0435-y Designed heterotrimers of collagen I, locked...
A TUNABLE ORTHOGONAL COILED-COIL INTERACTION TOOLBOX FOR ENGINEERING MAMMALIAN CELLS
Nature Chemical Biology, Published online: 06 January 2020; doi:10.1038/s41589-019-0443-y A set of orthogonal coiled-coil peptide heterodimers...
ALLOSTERIC MECHANISM FOR SITE-SPECIFIC UBIQUITINATION OF FANCD2
Nature Chemical Biology, Published online: 23 December 2019; doi:10.1038/s41589-019-0426-z UBE2T adopts an allosteric activation mechanism...
REGULATION OF PTP1B ACTIVATION THROUGH DISRUPTION OF REDOX-COMPLEX FORMATION
Nature Chemical Biology, Published online: 23 December 2019; doi:10.1038/s41589-019-0433-0 A transient interaction between 14-3-3ζ...
DYNAMICS OF TRANSCRIPTION-TRANSLATION COORDINATION TUNE BACTERIAL INDOLE SIGNALING
Nature Chemical Biology, Published online: 23 December 2019; doi:10.1038/s41589-019-0430-3 The authors utilize fluorescence-activated...
AN EFFICIENT GENE KNOCK-IN STRATEGY USING 5′-MODIFIED DOUBLE-STRANDED DNA DONORS WITH SHORT HOMOLOGY ARMS
Nature Chemical Biology, Published online: 23 December 2019; doi:10.1038/s41589-019-0432-1 A simple and effective strategy is introduced...
PUBLISHER CORRECTION: THE CHEMICAL BASIS OF FERROPTOSIS
Nature Chemical Biology, Published online: 02 January 2020; doi:10.1038/s41589-019-0434-z Publisher Correction: The chemical basis...
DECEMBER 2019 NEWSLETTER RELEASED!
The December newsletter was just released. BIOL members should have received it in their email. You can find the newsletter here .
FORGING A NEW CONNECTION
Nature Chemical Biology, Published online: 16 December 2019; doi:10.1038/s41589-019-0439-7 Forging a new connection
ARTIFICIAL SIGNALING IN MAMMALIAN CELLS ENABLED BY PROKARYOTIC TWO-COMPONENT SYSTEM
Nature Chemical Biology, Published online: 16 December 2019; doi:10.1038/s41589-019-0429-9 Bacterial two-component signaling machinery...
TRASHING TRANSCRIPTION
Nature Chemical Biology, Published online: 16 December 2019; doi:10.1038/s41589-019-0442-z Trashing transcription
World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
2nd International Conference on Tissue Science and Regenerative Medicine
This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...
Revolution Medicines Maps Out an IPO to Reach Cancer's Frontiers
Cancer research has revealed proteins known to play a role in the disease, but with no known way of stopping what they do. In pharmaceutical parlance, they're “undruggable.”... Read more ...
AveXis Inc.: Research Associate III
AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...
Mirati Therapeutics: Student Assistant
Mirati Therapeutics: Mirati Therapeutics is a targeted oncology company developing an advanced pipeline of breakthrough medicines for precisely defined patient populations San... Read more ...
Inhibition of lignification of Zizania latifolia with radio frequency...
Zizania latifolia is easily lignified after harvesting, leading to the degradation of food quality and commercial value. Thus, this study evaluated the effect of radio... Read more ...
Performance difference of graph-based and alignment-based hybrid error...
The error-prone third-generation sequencing long reads can be corrected by the high-quality second-generation sequencing short reads, which is referred to as hybrid error... Read more ...
CHROMATIX: computing the functional landscape of many-body chromatin...
Chromatin interactions are important for gene regulation and cellular specialization. Emerging evidence suggests many-body spatial interactions play important roles in... Read more ...
Bachem: Validation Engineer II, QA
Bachem: Your Responsibilities The Validation Engineer II fulfills a critical role in GMP operations. This individual must plan and execute validation studies, Vista, CA, US ... Read more ...
AveXis Inc.: Senior Scientist, Molecular Biology
AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...
Mirati Therapeutics: Talent Partner
Mirati Therapeutics: Reporting to the Head of Business, Culture and Talent this role will be partner with C-Level executive(s) and their staff. This role will be responsib San... Read more ...
Selective inhibition of matrix metalloproteinase 10 with a single-domain...
Since their discovery, the matrix metalloproteinase family of proteases have been considered as therapeutic targets in numerous diseases and disorders. Unfortunately, clinical... Read more ...