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ACS Division of Biological Chemistry

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FUNCTIONAL CHARACTERIZATION OF A PROTAC DIRECTED AGAINST BRAF MUTANT V600E

Nature Chemical Biology, Published online: 10 August 2020; doi:10.1038/s41589-020-0609-7 A PROTAC termed P4B targeting BRAF V600E mutant...

ACTIVE TURNOVER OF GENOMIC METHYLCYTOSINE IN PLURIPOTENT CELLS

Nature Chemical Biology, Published online: 10 August 2020; doi:10.1038/s41589-020-0621-y The combination of heavy isotope labeling...

 
 
 

A BIOLUMINESCENT PROBE FOR LONGITUDINAL MONITORING OF MITOCHONDRIAL MEMBRANE POTENTIAL

Nature Chemical Biology, Published online: 10 August 2020; doi:10.1038/s41589-020-0602-1 A mitochondria-activatable bioluminescent...

G12/13 IS ACTIVATED BY ACUTE TETHERED AGONIST EXPOSURE IN THE ADHESION GPCR ADGRL3

Nature Chemical Biology, Published online: 10 August 2020; doi:10.1038/s41589-020-0617-7 Among the adhesion receptor class of GPCRs,...

 
 
 

ORTHOGONAL FLUORESCENT CHEMOGENETIC REPORTERS FOR MULTICOLOR IMAGING

Nature Chemical Biology, Published online: 10 August 2020; doi:10.1038/s41589-020-0611-0 The fluorescent chemogenetic reporters greenFAST...

METABOLIC DETERMINANTS OF CANCER CELL SENSITIVITY TO CANONICAL FERROPTOSIS INDUCERS

Nature Chemical Biology, Published online: 10 August 2020; doi:10.1038/s41589-020-0613-y Genetic screens reveal a compendium of metabolic...

 
 
 

PUBLISHER CORRECTION: A MASS SPECTROMETRY-BASED PROTEOME MAP OF DRUG ACTION IN LUNG CANCER CELL LINES

Nature Chemical Biology, Published online: 11 August 2020; doi:10.1038/s41589-020-0643-5 Publisher Correction: A mass spectrometry-based...

ACS BIOL BROADCAST QUESTIONS AND DISCUSSION LINK

This Link will be open between 11:30 AM - 12:45 PM for the AM Broadcast Session and 2:30 - 3:45 PM for the PM Broadcast Session each...

 
 
 

A STRESS-FREE STRESS RESPONSE

Nature Chemical Biology, Published online: 23 July 2020; doi:10.1038/s41589-020-0616-8 A new molecule that specifically activates a...

PUBLISHER CORRECTION: ACOUSTIC BIOSENSORS FOR ULTRASOUND IMAGING OF ENZYME ACTIVITY

Nature Chemical Biology, Published online: 23 July 2020; doi:10.1038/s41589-020-0630-x Publisher Correction: Acoustic biosensors for...

 
 
 

LIVING CELLS AS TEST TUBES

Nature Chemical Biology, Published online: 24 July 2020; doi:10.1038/s41589-020-0615-9 Thermodynamic principles are used to map the...

ENZYMATIC C-H ACTIVATION OF AROMATIC COMPOUNDS THROUGH CO 2 FIXATION

Nature Chemical Biology, Published online: 27 July 2020; doi:10.1038/s41589-020-0603-0 Biocatalytic cascade reactions using engineered...

 
 
 

P63 USES A SWITCH-LIKE MECHANISM TO SET THE THRESHOLD FOR INDUCTION OF APOPTOSIS

Nature Chemical Biology, Published online: 27 July 2020; doi:10.1038/s41589-020-0600-3 TAp63α monitors the genome integrity in oocytes....

ENGINEERING ORTHOGONAL HUMAN O- LINKED GLYCOPROTEIN BIOSYNTHESIS IN BACTERIA

Nature Chemical Biology, Published online: 27 July 2020; doi:10.1038/s41589-020-0595-9 An orthogonal O-glycan biosynthesis system was...

 
 
 

NADP MODULATES RNA M 6 A METHYLATION AND ADIPOGENESIS VIA ENHANCING FTO ACTIVITY

Nature Chemical Biology, Published online: 27 July 2020; doi:10.1038/s41589-020-0601-2 NADP can directly bind with FTO and enhance...

CATASTROPHIC ACTIN FILAMENT BURSTING BY COFILIN, AIP1, AND CORONIN

Cofilin is an actin filament severing protein necessary for fast actin turnover dynamics. Coronin and Aip1 promote cofilin mediated...

 
 
 

EVIDENCE THAT POLYPHENOLS DO NOT INHIBIT THE PHOSPHOLIPID SCRAMBLASE TMEM16F

TMEM16 Ca2+-activated phospholipid scramblases mediate rapid trans-membrane phospholipid flip-flop and as such play essential roles...

SURVIVIN IN BREAST CANCER-DERIVED EXOSOMES ACTIVATES FIBROBLASTS BY UPREGULATING SOD1, WHOSE FEEDBACK PROMOTES CANCER PROLIFERATION AND METASTASIS

Cancer-associated fibroblasts play a critical role in the coevolution of breast tumor cells and their microenvironment by modifying...

 
 
 

H2S AND REACTIVE SULFUR SIGNALING AT THE HOST BACTERIAL PATHOGEN INTERFACE

Bacterial pathogens that cause invasive disease in the vertebrate host must adapt to host efforts to cripple their viability. Major...

DESIGNER PROTEIN ASSEMBLIES WITH TUNABLE PHASE DIAGRAMS IN LIVING CELLS

Nature Chemical Biology, Published online: 13 July 2020; doi:10.1038/s41589-020-0576-z A synthetic phase separation system consisting...

 
 
 



World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Advisory Body Backs MesoBlast Therapy for Transplant Complication

Advisory Body Backs MesoBlast Therapy for Transplant Complication

An FDA advisory committee Thursday voted 9-1 to recommend that the agency approve a stem cell therapy developed by MesoBlast as a treatment for acute graft-versus-host disease... Read more ...

CureVac's IPO Hauls In $213M as Key mRNA COVID-19 Vaccine Test Nears

CureVac's IPO Hauls In $213M as Key mRNA COVID-19 Vaccine Test Nears

CureVac is playing catch-up to its messenger RNA peers in the race to develop a COVID-19 vaccine, but the company contends its technology could offer dosing advantages, and it... Read more ...

Bio Roundup: Seres Soars, MesoBlast Vote, Duchenne Decision & More

Bio Roundup: Seres Soars, MesoBlast Vote, Duchenne Decision & More

The road of drug development is rife with detours and disappointments but Seres Therapeutics showed this week that course corrections can work. Four years after its microbiome... Read more ...

How COVID-19 Arose and Amplified Along the Meat Supply Chain

How COVID-19 Arose and Amplified Along the Meat Supply Chain

Early in this unforgettable year, a wet market in Wuhan, China, emerged as a possible step along the way, if not the place of origin, of the outbreak that would seed the... Read more ...

Global Methane Emissions Soaring, But How Much Was Due to Wetlands?

Global Methane Emissions Soaring, But How Much Was Due to Wetlands?

Infographic published with permission from the authors of “Increasing anthropogenic methane emissions arise equally from agricultural and fossil fuel sources.” (Credit: Jackson... Read more ...

Computer System Assurance: A Paradigm Shift Away from Compliance to Quality

Computer System Assurance: A Paradigm Shift Away from Compliance to Quality

Our Professional Services Written by: Gary E. Ritchie, MS, Senior Validation Engineer Consultant, PSC Biotech Corporation The FDA will release the draft guidance on Computer... Read more ...

Regulation of tumor necrosis superfamily molecules, BAFF and APRIL, in...

Abstract Tumor necrosis factor superfamily molecules are important inflammatory cytokines, which are involved in diverse immunological functions such as B-cell regulation and... Read more ...

Changes of water, sediment, and intestinal bacterial communities in Penaeus...

Abstract More and more studies have revealed a close relationship between gut microbial community and human health. However, the mechanism why changes in gut microflora... Read more ...

ACS BIOL Broadcast Questions and Discussion Link

This Link will be open between 11:30 AM - 12:45 PM for the AM Broadcast Session and 2:30 - 3:45 PM for the PM Broadcast Session each day. These times are Pacific Time. Read more ...

SQMtools: automated processing and visual analysis of 'omics data with R and...

The dramatic decrease in sequencing costs over the last decade has boosted the adoption of high-throughput sequencing applications as a standard tool for the analysis of... Read more ...