Therapeutics

An Automatable Hydrogel Culture Platform for Evaluating Efficacy of Antibody‐based Therapeutics in Overcoming Chemoresistance

7 monthes ago   |   By Wiley

The microenvironment plays a major role in conferring chemoresistance to cancer cells. In order to better inform clinical response to chemoresistance, preclinical models that recapitulate its hallmark features are needed to enable screening for resistance‐specific therapeutic targets. A novel platform for seeding cancer cells in 3D hydrogels is presented utilizing derivatives of chitosan and alginate that, critically, is amenable to high throughput screening: cell seeding in hydrogels, media changes, dosing of anticancer compounds, and cell viability assays were all automated using a...
Read more ...

 


Search by Tags

   Therapeutics      Clinical      Cancer      Protein      Drugs      Drug  


World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Galecto Picks Up $64M as Plans for Fibrosis Clinical Trials Move Forward

Galecto Picks Up $64M as Plans for Fibrosis Clinical Trials Move Forward

Had things turned out differently, scientists at Galecto might be watching their idiopathic pulmonary fibrosis drug candidate develop in the hands of a big pharmaceutical... Read more ...

Gel May Decrease Medical Device Blood Clotting, Infection Risk

Gel May Decrease Medical Device Blood Clotting, Infection Risk

As long as there have been medical devices ― mechanisms ranging from stents and tubing to catheters and implants ― patients have faced the risk of infections and blood... Read more ...

Material Scientists Learn How to Make Liquid Crystal Shape-shift

Material Scientists Learn How to Make Liquid Crystal Shape-shift

By controlling the printing temperature of liquid crystal elastomer, researchers have shown that they can vary the degree of stiffness and actuation in structures made from... Read more ...

Bio Roundup: Grail Acquisition, Libra's Launch, Tau Trial Results & More

Bio Roundup: Grail Acquisition, Libra's Launch, Tau Trial Results & More

In biotech, you can go home again. Four years ago, Illumina spun out cancer diagnostics startup Grail. This week, the gene sequencing giant announced it is acquiring Grail in... Read more ...

Combined Therapeutics Wins $250,000 MilliporeSigma Advance Biotech Grant

Combined Therapeutics Wins $250,000 MilliporeSigma Advance Biotech Grant

MilliporeSigma has awarded MIT spin-out Combined Therapeutics a check for $250,000 as the winner of its 2020 Advance Biotech Grant. Combined Therapeutics is an early stage... Read more ...

Machine Learning Takes on Synthetic Biology: Algorithms Can Bioengineer...

Machine Learning Takes on Synthetic Biology: Algorithms Can Bioengineer Cells for You

Tijana Radivojevic and Hector Garcia Martin working on mechanical and statistical modeling, data visualizations, and metabolic maps at the Agile BioFoundry last year. If... Read more ...

And the 2020 National Xconomy Awards Winners Are

And the 2020 National Xconomy Awards Winners Are

Congratulations to all the finalists and winners! This year we received over 600 nominations across 10 award categories. Each nomination was carefully reviewed and ranked by... Read more ...

Talking Alone: Researchers Use Artificial Intelligence Tools to Predict...

Talking Alone: Researchers Use Artificial Intelligence Tools to Predict Loneliness

A team led by researchers at University of California San Diego School of Medicine has used artificial intelligence technologies to analyze natural language patterns to discern... Read more ...

Imagion Biosystems, Inc.: Scientist / Senior Scientist

Imagion Biosystems, Inc.: Imagion Biosystems is looking for a motivated and experienced scientist to join our growing research and development team. San Diego, California ... Read more ...

A survey of the recent architectures of deep convolutional neural networks

Abstract Deep Convolutional Neural Network is a special type of Neural Networks, which has shown exemplary performance on several competitions related to Computer Vision and... Read more ...