Protein

Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathway

3 monthes ago   |   By Springer

Abstract
Receptor-interacting protein kinase 1/3 and mixed lineage kinase domain-like -mediated necroptosis contributes to brain injury after ischemic stroke. Ligustroflavone is an ingredient of common privet with activities of anti-inflammation and complement inhibition. This study aims to explore the effect of ligustroflavone on ischemic brain injury in stroke rat and the underlying mechanisms. A rat model of ischemic stroke was established by middle cerebral artery occlusion , which showed ischemic injury (increase in neurological deficit score and infarct volume) and upregulation of...
Read more ...

 


Search by Tags

   Protein      Neurology      Cellular      Brain  


World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

IAmScience Mannie Liscum

IAmScience Mannie Liscum

For Mannie Liscum, thinking is a privilege, and his job gives him the chance to be fascinated by human's capacity to conceptualize and learn new things. “It's my goal to use as... Read more ...

3 Takeaways From the Resurrection of Biogen's Alzheimer's Drug

3 Takeaways From the Resurrection of Biogen's Alzheimer's Drug

The name of the experimental drug was heard so frequently in hotel hallways at the conference that it sounded like an incantation: aducanumab, aducanumab, aducanumab... Read more ...

Acadia Looks to Expand Drug Beyond Parkinson's Disease Psychosis

Acadia Looks to Expand Drug Beyond Parkinson's Disease Psychosis

Acadia Pharmaceuticals revealed late-stage clinical data this week that could support bringing its drug for psychosis to a broader group of patients. The Acadia drug... Read more ...

FDA Puts Partial Hold on Tests of Ipsen Drug Acquired in $1B Deal

FDA Puts Partial Hold on Tests of Ipsen Drug Acquired in $1B Deal

Two clinical trials testing an Ipsen drug in rare connective tissue disorders have been placed on partial hold after safety concerns about chronic dosing of the compound... Read more ...

Bio Roundup: Biogen at CTAD, Sage's Stumble, Astellas's $3B Offer & More

Bio Roundup: Biogen at CTAD, Sage's Stumble, Astellas's $3B Offer & More

It's been a roller-coaster year for those hoping for new drugs to treat Alzheimer's disease, a leading cause of death with rising treatment costs and no clear answer yet as to... Read more ...

A Powerhouse of Cancer Research: A View from Florida

A Powerhouse of Cancer Research: A View from Florida

Nearly everyone has been affected by cancer , either through a personal diagnosis or that of a loved one. In the U.S., 1.7 million people are diagnosed each year, and over 15... Read more ...

Biogen Points to Enrollment and Dosing to Explain Alzheimer's Results

Biogen Points to Enrollment and Dosing to Explain Alzheimer's Results

Biogen revealed detailed results from its Alzheimer's trial to a jam-packed room of eager conference attendees this week-and while some described it as a major advance in the... Read more ...

Family with Two Rare Syndromes Reveals Immunity Glitch

Family with Two Rare Syndromes Reveals Immunity Glitch

Members of a three-generation family in France who suffer from widespread infections and fragile skin, joints, bones, and blood vessels share an underlying and unexpected... Read more ...

Application of A KNN‐based Similarity Method to Biopharmaceutical Manufacturing

Abstract Machine learning based similarity analysis is commonly found in many artificial intelligence applications like the one utilized in e‐commerce and digital marketing. In... Read more ...

Scientists detail how chromosomes reorganize after cell division

Researchers have discovered key mechanisms and structural details of a fundamental biological process - how a cell nucleus and its chromosomal material reorganizes itself after... Read more ...