Corticosteroids

FDA Flags Risk of Infection, Kidney Damage for Sarepta Duchenne Drugs

FDA Flags Risk of Infection, Kidney Damage for Sarepta Duchenne Drugs

26 days ago   |   Xconomy

Safety concerns stymied Sarepta Therapeutics' attempt to win FDA approval last August for golodirsen , its second Duchenne muscular dystrophy drug. But an appeal of the...
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Novartis chalks up another phase 3 asthma win as approval nears

4 monthes ago   |   Fierce Biotech

A phase 3 trial of Novartis' QMF149 in patients with uncontrolled asthma has met its primary endpoint. Novartis showed the drug combination is better at improving lung function...
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High-Dimensional Renal Profiling: Towards a Better Understanding of Renal Transplant Immune Suppression

One year ago   |   Springer

Abstract Purpose of Review The goal of this review is to discuss new approaches to avoid calcineurin inhibitor /corticosteroids toxicities with a focus on new biologics and new...
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EyeGate's anti-inflammatory eye drug and electric delivery device fail phase 3 trial

One year ago   |   Fierce Biotech

EyeGate Pharmaceuticals' corticosteroid treatment for noninfectious anterior uveitis-delivered directly into the ocular tissue via the company's device and a low-level electric...
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Hydrogel delivery enables long-lasting, ‘flare-responsive' arthritis treatment

One year ago   |   Fierce Biotech

Injectable drugs used to treat inflammatory arthritis are usually cleared quickly from joints, limiting their effectiveness. A PureTech startup is developing an...
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Splenectomy vs. rituximab as a second-line therapy in immune thrombocytopenic purpura: a single center experience

2 years ago   |   Springer

Abstract Immune thrombocytopenic purpura is a common hematological disease treated primarily by corticosteroids. The aim of the present study was to compare response rate...
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Sanofi: Dupilumab Significantly Reduced Steroid Use, Asthma Attacks, and Improved Lung Function i

2 years ago   |   BioSpace

Dupilumab added to standard therapies significantly reduced the use of maintenance oral corticosteroids by 70% on average.
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Impopharma And Breckenridge Pharmaceutical, Inc. Enter Into An Asset-Purchase Agreement To Commercialize The Generic Version Of A Leading Corticosteroid Product Upon FDA Approval

2 years ago   |   BioSpace   |   2 articles

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Langer's Kala files for $86M IPO to bring eye drug to market

2 years ago   |   Fierce Biotech

Kala Pharmaceuticals has filed to list on Nasdaq. The ophthalmic drug R&D shop has penciled in a fundraising goal of $86 million to equip itself to file for approvals of...
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Langer's Kala files for $86M IPO to bring eye drug to market

2 years ago   |   Fierce Biotech

Kala Pharmaceuticals has filed to list on Nasdaq. The ophthalmic drug R&D shop has penciled in a fundraising goal of $86 million to equip itself to file for approvals of...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

SPsimSeq: semi-parametric simulation of bulk and single cell RNA sequencing data

AbstractSummarySPsimSeq is a semi-parametric simulation method to generate bulk and single-cell RNA sequencing data. It is designed to simulate gene expression data with... Read more ...

SSIF: Subsumption-based Sub-term Inference Framework to Audit Gene Ontology

AbstractMotivationThe Gene Ontology is the unifying biological vocabulary for codifying, managing, and sharing biological knowledge. Quality issues in GO, if not addressed, can... Read more ...

Rejuvenate Bio: Senior Scientist-Cell Line Engineering and Virus Manufacturing

Rejuvenate Bio: Senior Scientist-Cell Line Engineering and Virus Manufacturing At Rejuvenate Bio, we aspire to treat aging and age-related diseases. We are a spino... San... Read more ...

Metabolomic analyses of the bio-corona formed on TiO2 nanoparticles...

The surface of a nanoparticle adsorbs molecules from its surroundings with a specific affinity determined by the chemical and physical properties of the nanomaterial. When a... Read more ...

Targeting of immunosuppressive myeloid cells from glioblastoma patients by...

Myeloid derived suppressor cells and tumor-associated macrophages are two of the major players involved in the inhibition of anti-tumor immune response in cancer patients... Read more ...

Discretely assembled walking machines

Abstract We introduce a discrete approach to robotic construction that enables the integration of structure, mechanism, and actuation and offers a promising route to on-demand... Read more ...

New Chip Brings Ultra-Low Power Wi-Fi Connectivity to IoT Devices

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Bioengineers developing organisms without biological parents

Bioengineers are on the brink of developing artificial organisms that will open up new applications in medicine and industry. Beat Christen discusses their risks and benefits. Read more ...

Neuropore Therapies Receives $500,000 Grant from The ALS Association to...

SAN DIEGO-- ALS-Neuropore Therapies receives a grant from The ALS Association... Read more ...

Functional characterization and circulating expression profile of...

Abstract Compelling evidence has shown that microRNAs are involved in the pathophysiology of BAV-associated aortopathy. The purpose of this study was to assess the biological... Read more ...