Checkpoint inhibitor

The effect of exercise on aromatase inhibitor-induced musculoskeletal symptoms in breast cancer survivors: a systematic review and meta-analysis

2 days ago   |   Springer

Abstract Background Evidence is mixed regarding the effect of exercise programs on improving musculoskeletal symptoms and quality of life. Previous meta-analyses have not...
Read more ...

Incyte hits endpoint in 2nd pivotal atopic dermatitis trial

5 days ago   |   Fierce Biotech

A second phase 3 trial of Incyte's ruxolitinib cream in atopic dermatitis has met its primary endpoint. The back-to-back pivotal successes tee Incyte up to talk to regulators...
Read more ...

Five Prime Therapeutics' pancreatic cancer combo with Opdivo a bust

5 days ago   |   Fierce Biotech

Wedding Five Prime Therapeutics' experimental CSF-1 receptor inhibitor cabiralizumab to Bristol-Myers Squibb's checkpoint inhibitor Opdivo has proved a bust in pancreatic cancer.
Read more ...

Natural based piperine derivatives as potent monoamine oxidase inhibitors: an in silico ADMET analysis and molecular docking studies

6 days ago   |   Chemistry Central

Neurodegenerative disorders follow numerous pathological ways concerning overexpression of monoamine oxidase and formation of reactive oxygen species. The computational design...
Read more ...

ALX raises $105M for midphase trials of CD47 cancer drug

12 days ago   |   Fierce Biotech

ALX Oncology has raised $105 million. The series C round will support phase 2 trials of CD47 myeloid checkpoint inhibitor ALX148 in combination with other anti-cancer therapies.
Read more ...

AXIM® Biotechnologies Acquiree Sapphire Biotech, Inc. Signs Sponsored Research Agreement with Arizona State University to Develop Metastatic Cancer Inhibitor

13 days ago   |   San Diego Biotechnology

SAN DIEGO, Feb. 10, 2020 - AXIM® Biotechnologies, Inc. (“AXIM® Biotech,” “AXIM” or “the Company”), an international healthcare solutions company targeting oncological and...
Read more ...

MicroRNA-143-5p modulates pulmonary artery smooth muscle cells functions in hypoxic pulmonary hypertension through targeting HIF-1α

13 days ago   |   Journal of Biosciences   |   2 articles

Abstract This paper explores the potential mechanism of microRNA-143-5p regulation effects on pulmonary artery smooth muscle cells functions in hypoxic pulmonary hypertension...
Read more ...

MiRNA-211 triggers an autophagy-dependent apoptosis in cervical cancer cells: regulation of Bcl-2

14 days ago   |   Springer

Abstract Cervical cancer is a significant cause of morbidity and mortality in gynecological malignancies. Although autophagy plays a critical role in affecting cell apoptosis...
Read more ...

Sanofi's phase 2 MS data spark broad push into late-stage trials

18 days ago   |   Fierce Biotech

A phase 2b clinical trial of Sanofi's BTK inhibitor SAR442168 in relapsing multiple sclerosis has met its primary endpoint. Sanofi responded to the data by outlining plans to...
Read more ...

Production of ent-kaurene from lignocellulosic hydrolysate in Rhodosporidium toruloides

18 days ago   |   Microbial Cell Factories

Rhodosporidium toruloides has emerged as a promising host for the production of bioproducts from lignocellulose, in part due to its ability to grow on lignocellulosic...
Read more ...


Register you to post on BioTech Mag

Free Registration

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Invetx Fetches $15M to Develop Biologic Drugs for Man's Best Friend

Invetx Fetches $15M to Develop Biologic Drugs for Man's Best Friend

Veterinarians have a saying that a cat is not a small dog, says Invetx CEO Juergen Horn. Obviously, a dog of any size isn't the same as a human. But Horn, a veterinarian, says... Read more ...

Lundbeck's Alder Bio Bet Pays Off With FDA Approval of Migraine Drug

Lundbeck's Alder Bio Bet Pays Off With FDA Approval of Migraine Drug

A migraine drug that Lundbeck added to its pipeline via its nearly $2 billion acquisition of Alder BioPharmaceuticals won FDA approval on Friday. The drug, eptinezumab , is... Read more ...

Bonus Episode of TBD: Europe's New AI Strategy

Tech Policy is a rapidly evolving field, and from time-to-time we hope to release these bonus episodes to give you some insight into things as they're happening in real-time... Read more ...

Arima Genomics Completes Series A Financing

SAN DIEGO--Arima Genomics, Inc., a company focused on research tools to accelerate the understanding of genome sequence and structure toward their role in human health and... Read more ...

Viking Therapeutics to Participate in Upcoming Investor Conferences

SAN DIEGO, Feb. 24, 2020 /PRNewswire/ - Viking Therapeutics, Inc. , a clinical-stage biopharmaceutical company focused on the development of novel therapies for metabolic and... Read more ...

Molecular characterization and overexpression analyses of secologanin...

Abstract Camptothecin is a high-value anti-cancerous compound produced in many taxonomically unrelated species. Its biosynthesis involves a complex network of pathways and a... Read more ...

Modulation of the Purine Pathway for Riboflavin Production in Flavinogenic...

Riboflavin is an indispensable nutrient for humans and animals, since it is the precursor of the essential coenzymes FMN and FAD, involved in variety of metabolic reactions... Read more ...

A Critical Review of Genome Editing and Synthetic Biology Applications in...

Being the green gold of the future, microalgae and cyanobacteria have recently attracted considerable interest worldwide, for they can be used to produce different kinds of... Read more ...

Biodegradation of penicillin G from industrial bacteria residue by...

An efficient biodegradation-strengthening approach was developed to improve penicillin G degradation from industrial bacterial residue in an expanded bed adsorption bioreactor... Read more ...

More clues for how the monkeyflower got its spots

The monkeyflower, or Mimulus, though possessing a relatively simple genome is able to produce a stunning array of pigmentation patterns. A team of researchers is one step... Read more ...