Cancer

Mismatch repair gene pathogenic germline variants in a population-based cohort of breast cancer

11 days ago   |   By Springer

Abstract
The advent of gene panel testing is challenging the previous practice of using clinically defined cancer family syndromes to inform single-gene genetic screening. Individual and family cancer histories that would have previously indicated testing of a single gene or a small number of related genes are now, increasingly, leading to screening across gene panels that contain larger numbers of genes. We have applied a gene panel test that included four DNA mismatch repair genes to an Australian population-based case-control-family study of breast cancer. Altogether, eight pathogenic...
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Waiting and “weighted down”: the challenge of anticipatory loss for individuals and families with Li-Fraumeni Syndrome

11 days ago   |   By Springer

Abstract
Li-Fraumeni Syndrome is characterized by risk of multiple primary malignancies in diverse sites, pediatric onset, near complete penetrance by age 70 years, limited options for prevention, and substantial uncertainty regarding disease manifestation and prognosis. Forty-five families, including 117 individuals aged 13-81 years, enrolled in the US National Cancer Institute's Li-Fraumeni Syndrome Study completed 66 interviews regarding their LFS experiences. An interdisciplinary team used modified grounded theory to examine family distress regarding expectations of loss and change due...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

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104714 Patient Navigator - Contract Appointment

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How a new biotech rule will foster distrust with the public and impede...

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FloChiP, a new tool optimizing gene-regulation studies

In the cell, proteins often interact directly with DNA to regulate and influence the expression of genes. For this to happen, proteins need to travel into the cell's nucleus... Read more ...

Researchers control cattle microbiomes to reduce methane and greenhouse gases

Ben-Gurion University of the Negev researchers have learned to control the microbiome of cattle for the first time which could inhibit their methane production, and therefore... Read more ...

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Gossamer Bio Announces Participation in Upcoming Investor Conferences

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DelMar Pharmaceuticals to Present Updates of Two Phase 2 Clinical Trials of...

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