Biosciences

Spruce Bio Raises $88M for Clinical Tests of Rare Endocrine Disease Drug

1 month ago   |   By Xconomy

Spruce Biosciences has raised $88 million to advance clinical testing of a drug for a rare inherited endocrine disorder that can lead to a potentially life-threatening hormonal imbalance. San Francisco-based Spruce aims to treat a form of congenital adrenal hyperplasia , an inherited condition that leads to a deficiency in enzymes needed to produce certain hormones, which in turn leads to the overproduction of other hormones. The disease stems from a mutation in the gene that encodes 21-hydroxylase, an enzyme key to the production of adrenal hormones. Spruce aims to treat classical CAH...
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