Tissue

Molecular characterization and overexpression analyses of secologanin synthase to understand the regulation of camptothecin biosynthesis in Nothapodytes nimmoniana Mabb

4 hours ago   |   Springer

Abstract Camptothecin is a high-value anti-cancerous compound produced in many taxonomically unrelated species. Its biosynthesis involves a complex network of pathways and a...
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Scientists develop more accurate stem-cell model of early developing mouse embryo

19 hours ago   |   ScienceDaily   |   2 articles

Scientists have managed to generate complex embryo-like structures from mouse embryonic stem cells. These structures, called gastruloids, can now for the first time grow...
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Deleterious Non-Synonymous Single Nucleotide Polymorphism Predictions on Human Transcription Factors

3 days ago   |   IEEE/ACM

Transcription factors are the major components of human gene regulation. In particular, they bind onto specific DNA sequences and regulate neighborhood genes in different...
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Mammalian Pericardium‐Based Bioprosthetic Materials in Xenotransplantation and Tissue Engineering

3 days ago   |   Wiley

Abstract Bioprosthetic materials based on mammalian pericardium tissue are the gold standard in reconstructive surgery. Their application range covers repair of rectovaginal...
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LncRNA COL1A1-014 is involved in the progression of gastric cancer via regulating CXCL12-CXCR4 axis

4 days ago   |   Springer   |   2 articles

Abstract Background The aberrant expression of long noncoding RNAs is found in various types of cancers and also showed its association with the occurrence and development of...
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Increasing growth and yield by altering carbon metabolism in a transgenic leaf oil crop

5 days ago   |   Wiley

Abstract Engineering high biomass plants that produce oil in vegetative rather than seed‐related tissues could help meet our growing demand for plant oil. Several studies have...
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LncRNA XIST interacts with miR-454 to inhibit cells proliferation, epithelial mesenchymal transition and induces apoptosis in triple-negative breast cancer

5 days ago   |   Journal of Biosciences

Abstract Triple-negative breast cancer is a one of the subtypes of breast cancer which accounts for approximately 10-20% of all breast cancers. LncRNA XIST is reported to be...
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SPECS: a non-parametric method to identify tissue-specific molecular features for unbalanced sample groups

6 days ago   |   BMC Bioinformatics

To understand biology and differences among various tissues or cell types, one typically searches for molecular features that display characteristic abundance patterns. Several...
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Metabolomic analyses of the bio-corona formed on TiO2 nanoparticles incubated with plant leaf tissues

6 days ago   |   Journal of Nanobiotechnology

The surface of a nanoparticle adsorbs molecules from its surroundings with a specific affinity determined by the chemical and physical properties of the nanomaterial. When a...
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On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability

8 days ago   |   ACS Division of Biological Chemistry

Expansions of simple tandem repeats are responsible for almost 50 human diseases, the majority of which are severe, degenerative, and not currently treatable or preventable. In...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Invetx Fetches $15M to Develop Biologic Drugs for Man's Best Friend

Invetx Fetches $15M to Develop Biologic Drugs for Man's Best Friend

Veterinarians have a saying that a cat is not a small dog, says Invetx CEO Juergen Horn. Obviously, a dog of any size isn't the same as a human. But Horn, a veterinarian, says... Read more ...

Lundbeck's Alder Bio Bet Pays Off With FDA Approval of Migraine Drug

Lundbeck's Alder Bio Bet Pays Off With FDA Approval of Migraine Drug

A migraine drug that Lundbeck added to its pipeline via its nearly $2 billion acquisition of Alder BioPharmaceuticals won FDA approval on Friday. The drug, eptinezumab , is... Read more ...

Arima Genomics Completes Series A Financing

SAN DIEGO--Arima Genomics, Inc., a company focused on research tools to accelerate the understanding of genome sequence and structure toward their role in human health and... Read more ...

Viking Therapeutics to Participate in Upcoming Investor Conferences

SAN DIEGO, Feb. 24, 2020 /PRNewswire/ - Viking Therapeutics, Inc. , a clinical-stage biopharmaceutical company focused on the development of novel therapies for metabolic and... Read more ...

Molecular characterization and overexpression analyses of secologanin...

Abstract Camptothecin is a high-value anti-cancerous compound produced in many taxonomically unrelated species. Its biosynthesis involves a complex network of pathways and a... Read more ...

Modulation of the Purine Pathway for Riboflavin Production in Flavinogenic...

Riboflavin is an indispensable nutrient for humans and animals, since it is the precursor of the essential coenzymes FMN and FAD, involved in variety of metabolic reactions... Read more ...

A Critical Review of Genome Editing and Synthetic Biology Applications in...

Being the green gold of the future, microalgae and cyanobacteria have recently attracted considerable interest worldwide, for they can be used to produce different kinds of... Read more ...

Biodegradation of penicillin G from industrial bacteria residue by...

An efficient biodegradation-strengthening approach was developed to improve penicillin G degradation from industrial bacterial residue in an expanded bed adsorption bioreactor... Read more ...

More clues for how the monkeyflower got its spots

The monkeyflower, or Mimulus, though possessing a relatively simple genome is able to produce a stunning array of pigmentation patterns. A team of researchers is one step... Read more ...

A deep dive into cellular aging

Scientists have discovered that mitochondria trigger senescence, the sleep-like state of aged cells, through communication with the cell's nucleus -a nd identified an... Read more ...