Therapies

Mouse model for endometriosis is characterized by proliferation and inflammation but not epithelial-to-mesenchymal transition and fibrosis

11 hours ago   |   Journal of Biosciences

Abstract Endometriosis is a common disorder of unknown etiology, and non-surgical therapies are still a challenge. To understand the pathogenesis and preclinical testing of...
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Scholar Rock's experimental SMA therapy nabs speedy review voucher

22 hours ago   |   Fierce Biotech

Scholar Rock's experimental SMA therapy nabs speedy review voucher badams Thu, 08/13/2020 - 08:36
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Passage Bio slapped with gene therapy clinical hold

1 day ago   |   Fierce Biotech

Passage Bio slapped with gene therapy clinical hold ntaylor Thu, 08/13/2020 - 08:31
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Retrophin: Director, Scientific Communications

1 day ago   |   San Diego Biotechnology

Retrophin: At Retrophin, our mission is to identify, develop and deliver life-changing therapies to people living with rare disease. Giving patients a chance, pr San Diego...
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Sorrento Therapeutics, Inc.: Scientist/Senior Scientist

1 day ago   |   San Diego Biotechnology   |   5 articles

DOE+Benefits+Options: Sorrento Therapeutics, Inc.: ABOUT US Sorrento Therapeutics Inc. is a fast growing, clinical stage, antibody-centric, biopharmaceutical company developing...
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SMN1 gene copy number analysis for spinal muscular atrophy in a Turkish cohort by CODE-SEQ technology, an integrated solution for detection of SMN1 and SMN2 copy numbers and the “2+0” genotype

3 days ago   |   Springer

Abstract Introduction Spinal muscular atrophy is one of the common autosomal recessive disorders with global heterozygous carrier frequency of 1:50. Due to high carrier...
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Recognition of LD motifs by the Focal Adhesion Targeting Domains of FAK and PYK2: Insights from Molecular Dynamics Simulations

3 days ago   |   Wiley

Abstract The focal adhesion kinase and the proline‐rich tyrosine kinase 2‐beta are implicated in cancer progression and metastasis and represent promising biomarkers and...
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Retrophin: Regulatory Operations Coordinator

3 days ago   |   San Diego Biotechnology

Retrophin: At Retrophin, our mission is to identify, develop and deliver life-changing therapies to people living with rare disease. Giving patients a chance, pr San Diego...
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Overexpression miR-486-3p Promoted by Allicin Enhances Temozolomide Sensitivity in Glioblastoma Via Targeting MGMT

3 days ago   |   Springer

Abstract Glioblastoma is the most common primary tumor of the central nervous system that develops chemotherapy resistance. Previous studies showed that Allicin could inhibit...
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Seres Sets Sights on FDA After C. Diff Microbiome Therapy Scores in Phase 3

Seres Sets Sights on FDA After C. Diff Microbiome Therapy Scores in Phase 3

4 days ago   |   Xconomy

An experimental Seres Therapeutics capsule of live bacteria has met the goals of a pivotal study evaluating it as a treatment for a type of recurrent gut infection, preliminary...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

How COVID-19 Arose and Amplified Along the Meat Supply Chain

How COVID-19 Arose and Amplified Along the Meat Supply Chain

Early in this unforgettable year, a wet market in Wuhan, China, emerged as a possible step along the way, if not the place of origin, of the outbreak that would seed the... Read more ...

Global Methane Emissions Soaring, But How Much Was Due to Wetlands?

Global Methane Emissions Soaring, But How Much Was Due to Wetlands?

Infographic published with permission from the authors of “Increasing anthropogenic methane emissions arise equally from agricultural and fossil fuel sources.” (Credit: Jackson... Read more ...

Computer System Assurance: A Paradigm Shift Away from Compliance to Quality

Computer System Assurance: A Paradigm Shift Away from Compliance to Quality

Our Professional Services Written by: Gary E. Ritchie, MS, Senior Validation Engineer Consultant, PSC Biotech Corporation The FDA will release the draft guidance on Computer... Read more ...

With FDA Nod, NS Pharma Duchenne Drug Becomes Sarepta Competitor

With FDA Nod, NS Pharma Duchenne Drug Becomes Sarepta Competitor

Duchenne muscular dystrophy patients whose disease is characterized by a particular genetic mutation now have a new treatment option following the FDA's Wednesday approval of a... Read more ...

Perceptive Advisors' LianBio Inks Deals With BridgeBio, MyoKardia

Perceptive Advisors' LianBio Inks Deals With BridgeBio, MyoKardia

Two California biotechs have teamed up with LianBio, a new company launched earlier this week by hedge fund Perceptive Advisors, as part of deals that expand their reach into... Read more ...

F2G Lands $60M for a New Tack on Taking Out Rare Fungal Infections

F2G Lands $60M for a New Tack on Taking Out Rare Fungal Infections

Fungal infections might not immediately come to mind as rare diseases, but growing resistance to older drugs means that patients who develop these infections have limited... Read more ...

Calliditas gets controlling stake, option to buy out Genkyotex and its...

Calliditas gets controlling stake, option to buy out Genkyotex and its failed PBC drug badams Fri, 08/14/2020 - 05:07 Read more ...

17β-Estradiol affects the innate immune response in common carp

Abstract Inflammation is the evolutionary conserved immune response to harmful stimuli such as pathogens or damaged cells. This multistep process acts by removing injurious... Read more ...

Chutes & Ladders-WuXi taps veteran operations head Dong to lead new vaccines...

Chutes & Ladders-WuXi taps veteran operations head Dong to lead new vaccines unit kblankenship Fri, 08/14/2020 - 08:23 Read more ...

Team discovers a new role for a well-known molecule as a plant hormone

Researchers at the University of Maryland have discovered an entirely new role for a well-known plant molecule called ACC, providing the first clear example of ACC acting on... Read more ...