Therapeutics

Comparative transcriptomics reveals PrrAB-mediated control of metabolic, respiration, energy-generating, and dormancy pathways in Mycobacterium smegmatis

20 hours ago   |   Springer

Abstract Background Mycobacterium smegmatis is a saprophytic bacterium frequently used as a genetic surrogate to study pathogenic Mycobacterium tuberculosis. The PrrAB...
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3 Takeaways From the Resurrection of Biogen's Alzheimer's Drug

3 Takeaways From the Resurrection of Biogen's Alzheimer's Drug

22 hours ago   |   Xconomy

The name of the experimental drug was heard so frequently in hotel hallways at the conference that it sounded like an incantation: aducanumab, aducanumab, aducanumab...
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Ovarian cancer stem cells and targeted therapy

1 day ago   |   Springer

Abstract Background Ovarian cancer has the highest ratio of mortality among gynecologic malignancies. Chemotherapy is one of the most common treatment options for ovarian...
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Fate Therapeutics: Scientist / Associate Scientist, Protein Chemistry/Molecular Engineering

2 days ago   |   San Diego Biotechnology

Fate Therapeutics: individual with expertise in protein chemistry and molecular biology to join a team dedicated to discovery and productization of novel cell therapies 92121...
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Sage crushed by MOUNTAIN as phase 3 depression data fall short

2 days ago   |   Fierce Biotech   |   2 articles

Sage Therapeutics' key phase 3 trial in major depressive disorder has missed its primary endpoint. The failure of SAGE-217 to beat placebo wiped more than 50% off Sage's share...
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Regulatory Affairs Associate - Sorrento Therapeutics - San Diego, CA

2 days ago   |   San Diego Biotechnology   |   3 articles

Utilize systems and tools for electronic document capture, generation, manipulation, scanning, and QC. Ensure final document components are electronically...From Sorrento...
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Quality Control Scientist - Sorrento Therapeutics - San Diego, CA

2 days ago   |   San Diego Biotechnology   |   3 articles

Conduct QC tests following test protocols and procedures in compliance with quality system and cGMP regulations. WHAT WE ARE LOOKING FOR:From Sorrento Therapeutics - Thu, 05...
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Sage Therapeutics Depression Drug Fails in Phase 3, Shares Fall 60%

Sage Therapeutics Depression Drug Fails in Phase 3, Shares Fall 60%

2 days ago   |   Xconomy   |   2 articles

An experimental Sage Therapeutics drug intended to alleviate depression symptoms quickly has failed to beat a placebo in a pivotal study, the company reported Thursday...
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In vitro apoptotic effect on human lymphatic filarial parasite by piperidine derivatives and thymidine reversal study

2 days ago   |   Springer

Abstract A novel library of synthetic piperidine derivatives was used to screen against human lymphatic filarial parasite Brugia malayi. Piperidine has earlier been reported to...
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Civetta Therapeutics Unveils a Propeller Protein Plan, $53M in Funding

Civetta Therapeutics Unveils a Propeller Protein Plan, $53M in Funding

3 days ago   |   Xconomy

New biotech company Civetta Therapeutics has closed a $53 million Series A financing round to develop drugs that target “propeller proteins” as a way of treating cancers and...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

IAmScience Mannie Liscum

IAmScience Mannie Liscum

For Mannie Liscum, thinking is a privilege, and his job gives him the chance to be fascinated by human's capacity to conceptualize and learn new things. “It's my goal to use as... Read more ...

3 Takeaways From the Resurrection of Biogen's Alzheimer's Drug

3 Takeaways From the Resurrection of Biogen's Alzheimer's Drug

The name of the experimental drug was heard so frequently in hotel hallways at the conference that it sounded like an incantation: aducanumab, aducanumab, aducanumab... Read more ...

Acadia Looks to Expand Drug Beyond Parkinson's Disease Psychosis

Acadia Looks to Expand Drug Beyond Parkinson's Disease Psychosis

Acadia Pharmaceuticals revealed late-stage clinical data this week that could support bringing its drug for psychosis to a broader group of patients. The Acadia drug... Read more ...

FDA Puts Partial Hold on Tests of Ipsen Drug Acquired in $1B Deal

FDA Puts Partial Hold on Tests of Ipsen Drug Acquired in $1B Deal

Two clinical trials testing an Ipsen drug in rare connective tissue disorders have been placed on partial hold after safety concerns about chronic dosing of the compound... Read more ...

Bio Roundup: Biogen at CTAD, Sage's Stumble, Astellas's $3B Offer & More

Bio Roundup: Biogen at CTAD, Sage's Stumble, Astellas's $3B Offer & More

It's been a roller-coaster year for those hoping for new drugs to treat Alzheimer's disease, a leading cause of death with rising treatment costs and no clear answer yet as to... Read more ...

A Powerhouse of Cancer Research: A View from Florida

A Powerhouse of Cancer Research: A View from Florida

Nearly everyone has been affected by cancer , either through a personal diagnosis or that of a loved one. In the U.S., 1.7 million people are diagnosed each year, and over 15... Read more ...

Biogen Points to Enrollment and Dosing to Explain Alzheimer's Results

Biogen Points to Enrollment and Dosing to Explain Alzheimer's Results

Biogen revealed detailed results from its Alzheimer's trial to a jam-packed room of eager conference attendees this week-and while some described it as a major advance in the... Read more ...

Family with Two Rare Syndromes Reveals Immunity Glitch

Family with Two Rare Syndromes Reveals Immunity Glitch

Members of a three-generation family in France who suffer from widespread infections and fragile skin, joints, bones, and blood vessels share an underlying and unexpected... Read more ...

Application of A KNN‐based Similarity Method to Biopharmaceutical Manufacturing

Abstract Machine learning based similarity analysis is commonly found in many artificial intelligence applications like the one utilized in e‐commerce and digital marketing. In... Read more ...

Scientists detail how chromosomes reorganize after cell division

Researchers have discovered key mechanisms and structural details of a fundamental biological process - how a cell nucleus and its chromosomal material reorganizes itself after... Read more ...