Research

CRISPR System: A High-throughput Toolbox for Research and Treatment of Parkinson's Disease

4 hours ago   |   Springer

Abstract In recent years, the innovation of gene-editing tools such as the CRISPR/Cas9 system improves the translational gap of treatments mediated by gene therapy. The...
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MiR-552 promotes ovarian cancer progression by regulating PTEN pathway

5 hours ago   |   Springer   |   2 articles

Abstract Background Increasing researches have demonstrated the critical functions of MicroRNAs in the progression of malignant tumors, including ovarian cancer. It was...
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A New Risk-Based Fuzzy Cognitive Model and Its Application to Decision-Making

6 hours ago   |   Springer

Abstract Cognitive information in real-world decision-making problems is usually associated with all sorts of ambiguities and uncertainties. Fuzzy sets have been proposed as a...
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Understanding sheath blight resistance in rice: the road behind and the road ahead

17 hours ago   |   Wiley

Abstract Rice Sheath blight disease, caused by the basidiomycetous necrotrophy Rhizoctonia solani, became one of the major threats to the rice cultivation worldwide, especially...
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IRGD-guided tamoxifen polymersomes inhibit estrogen receptor transcriptional activity and decrease the number of breast cancer cells with self-renewing capacity

1 day ago   |   Journal of Nanobiotechnology

Tamoxifen is the most frequent treatment for estrogen receptor positive breast cancer. We recently showed that fibronectin leads to Tam resistance and selection of breast...
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A novel fluorescent biosensor based on dendritic DNA nanostructure in combination with ligase reaction for ultrasensitive detection of DNA methylation

1 day ago   |   Journal of Nanobiotechnology

DNA methylation detection is indispensable for the diagnosis and prognosis of various diseases including malignancies. Hence, it is crucial to develop a simple, sensitive, and...
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Chromosome-level genome assembly for giant panda provides novel insights into Carnivora chromosome evolution

1 day ago   |   Genome Biology

Chromosome evolution is an important driver of speciation and species evolution. Previous studies have detected chromosome rearrangement events among different Carnivora...
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Scientists detail how chromosomes reorganize after cell division

1 day ago   |   ScienceDaily

Researchers have discovered key mechanisms and structural details of a fundamental biological process - how a cell nucleus and its chromosomal material reorganizes itself after...
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What does DNA's repair shop look like? New research identifies the tools

1 day ago   |   ScienceDaily

A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how the body works to ensure its...
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Physical forces affect bacteria's toxin resistance, study finds

1 day ago   |   ScienceDaily

A random conversation between two researchers at a child's birthday party led to a collaboration and new understanding of how bacteria resist toxins, which may lead to new...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

IAmScience Mannie Liscum

IAmScience Mannie Liscum

For Mannie Liscum, thinking is a privilege, and his job gives him the chance to be fascinated by human's capacity to conceptualize and learn new things. “It's my goal to use as... Read more ...

New Sanofi CEO Hudson adds next-gen cancer drug tech to the R&D quest...

When Paul Hudson lays out his R&D vision for Sanofi tomorrow, he will have a new slate of interleukin therapies and a synthetic biology platform to boast about. The French... Read more ...

AveXis Inc.: Senior Scientific Training Specialist - cGMP Gene Therapy

AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...

Process Engineer I - Genentech - Oceanside, CA

Focus will be on one or more areas such as design, implementation and/or start-up of new and/or existing facilities with respect to process and/or clean utility...From... Read more ...

Pineoblastoma segregates into molecular sub-groups with distinct...

Abstract Pineoblastomas are rare, aggressive pediatric brain tumors of the pineal gland with modest overall survival despite intensive therapy. We sought to define the clinical... Read more ...

The majority of A-to-I RNA editing is not required for mammalian homeostasis

Abstract Background Adenosine-to-inosine RNA editing, mediated by ADAR1 and ADAR2, occurs at tens of thousands to millions of sites across mammalian transcriptomes. A-to-I... Read more ...

CRISPR System: A High-throughput Toolbox for Research and Treatment of...

Abstract In recent years, the innovation of gene-editing tools such as the CRISPR/Cas9 system improves the translational gap of treatments mediated by gene therapy. The... Read more ...

Exploration of cryptic organic photosensitive compound as Zincphyrin IV in...

Abstract Zincphyrin IV is a potential organic photosensitizer which is of significant interest for applications in biomedicine, materials science, agriculture , and chemistry... Read more ...

Three transcriptional regulators positively regulate the biosynthesis of...

Abstract Polycyclic tetramate macrolactams are a widely distributed class of structurally complex natural products, and most of them exhibit multiple biological activities... Read more ...

Faint gray bands in Drosophila melanogaster polytene chromosomes are formed...

Abstract In Drosophila melanogaster , the chromatin of interphase polytene chromosomes appears as alternating decondensed interbands and dense black or thin gray bands... Read more ...