9 hours ago | ScienceDaily

Using high-throughput next-generation sequencing technology, a researcher found similarities in the folding tendencies among a family of RNA molecules called riboswitches...
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DeepImpute: an accurate, fast, and scalable deep neural network method to impute single-cell RNA-seq data

2 days ago | Genome Biology

Single-cell RNA sequencing offers new opportunities to study gene expression of tens of thousands of single cells simultaneously. We present DeepImpute, a deep neural...
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Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses

4 days ago | Genome Biology

Single-cell RNA sequencing is a powerful tool for studying complex biological systems, such as tumor heterogeneity and tissue microenvironments. However, the sources of...
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DPre: Computational identification of differentiation bias and genes underlying cell type conversions

4 days ago | Oxford Journals

AbstractSummaryCells are generally resistant to cell type conversions, but can be converted by the application of growth factors, chemical inhibitors and ectopic expression of...
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Engineering plants virus resistance: from RNA silencing to genome editing strategies

4 days ago | Wiley

Abstract Viral diseases severely affect crop yield and quality, thereby threatening global food security. Genetic improvement of plant virus resistance is essential for...
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IRNA-PseTNC: identification of RNA 5-methylcytosine sites using hybrid vector space of pseudo nucleotide composition

5 days ago | Springer

Abstract RNA 5-methylcytosine sites perform a major role in numerous biological processes and commonly reported in both DNA and RNA cellular. The enzymatic mechanism and...
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DIRECT: RNA contact predictions by integrating structural patterns

6 days ago | BMC Bioinformatics

It is widely believed that tertiary nucleotide-nucleotide interactions are essential in determining RNA structure and function. Currently, direct coupling analysis infers...
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Alternative role of noncoding RNAs: coding and noncoding properties

6 days ago | Springer

概要非编码 RNA 在细胞生物学功能中发挥着重要作用。近年来, 研究人员在生物发育和多种疾病中发现了一些由非编码 RNA 编码产生的多肽或蛋白质。在本文中, 我们简要总结了几种由 ncRNA 翻译的微肽分子及其功能。此外, 我们还总结了调控 ncRNA 的可能机制, 并且提出了一个生物 “开关”, 即细胞在一定的刺激或应激状态下...
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Mapping spatial transcriptome with light-activated proximity-dependent RNA labeling

6 days ago | ACS Division of Biological Chemistry | 7 articles

Nature Chemical Biology, Published online: 07 October 2019; doi:10.1038/s41589-019-0368-5 A light-activated RNA labeling method was developed to determine spatial organization...
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Screening for differential expression of genes for resistance to Sitodiplosis mosellana in bread wheat via BSR-seq analysis

7 days ago | Springer

Abstract Key message Five putative candidate genes for OWBM resistance in Chinese winter wheat ‘Jimai 24' were identified via BSR-seq and differential expression...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

SeaGen to Seek FDA Nod After Breast Cancer Drug Hits Goals of Key Study

An experimental breast cancer drug from Seattle Genetics is headed for FDA review after the company reported a pivotal clinical trial met its main goals. The company has been... Read more ...

Backed by $50M, Verseau Launches to Reprogram Immune Cells Against Cancer

Cancer therapies that harness the immune system don't work for all patients. Verseau Therapeutics aims to bring cancer immunotherapy to more people by targeting a type of... Read more ...

The secret of classic Belgian beers? Medieval super-yeasts

An international team of scientists led by Prof. Kevin Verstrepen and Prof. Steven Maere has discovered that some of the most renowned classic Belgian beers, including Gueuze... Read more ...

Edible grasshoppers can be modified for better fatty acid composition

It is possible to modify the fatty acid composition of edible grasshoppers by adding essential fatty acids in their feed, new research from the University of Eastern Finland... Read more ...

Manager, Engineering - Bachem - Vista, CA

The company provides a full range of services to the pharma and biotech industries. Handle complete project life cycle from design, planning and implementation...From Bachem... Read more ...

Bayer backs off running Casebia JV, as CRISPR Tx takes over management

Three years after Bayer and gene-editing biotech CRISPR Therapeutics joined forces to launch and run Casebia Therapeutics, the German Pharma is now handing over the full reins... Read more ...

Uncovering the principles behind RNA folding

Using high-throughput next-generation sequencing technology, a researcher found similarities in the folding tendencies among a family of RNA molecules called riboswitches... Read more ...

Listening in to how proteins talk and learning their language

A research team has created a third approach to engineering proteins that uses deep learning to distill the fundamental features of proteins directly from their amino acid... Read more ...

Pinpointing biomolecules with nanometer accuracy

Scientists demonstrate a new approach in fluorescence microscopy that can be used to locate individual biomolecules in 3D space with nanometer-scale precision. Read more ...

How the mouse X and Y chromosomes compete with each other to control offspring

New research presents the first demonstration of a specific difference in sperm function associated with sex ratio skewing. Read more ...