Protein

New Amino Acid Substitution Matrix Brings Sequence Alignments into Agreement with Structure Matches

2 hours ago   |   Wiley

Abstract Protein sequence matching presently fails to identify many structures that are highly similar, even when they are known to have the same function. The high packing...
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CircTP53 promotes the proliferation of thyroid cancer via targeting miR-1233-3p/MDM2 axis

5 hours ago   |   Springer

Abstract Background Follicular cells give rise to thyroid cancer. Worldwide thyroid cancer incidence continues to rise in recent decades but the mortality rate remains at a...
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Study on functional sites in human multidrug resistance protein 1

14 hours ago   |   Wiley

ABSTRACT Human multidrug resistance protein 1 is an important member of the ATP‐binding cassette transporter superfamily. It can extrude a variety of anticancer drugs and...
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DeepSurf: A surface-based deep learning approach for the prediction of ligand binding sites on proteins

15 hours ago   |   Oxford Journals   |   2 articles

AbstractMotivationThe knowledge of potentially druggable binding sites on proteins is an important preliminary step towards the discovery of novel drugs. The computational...
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PrInCE: an R/bioconductor package for protein-protein interaction network inference from co-fractionation mass spectrometry data

15 hours ago   |   Oxford Journals

AbstractSummaryWe present PrInCE, an R/Bioconductor package that employs a machine-learning approach to infer protein-protein interaction networks from co-fractionation mass...
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SWOTein: a structure-based approach to predict stability Strengths and Weaknesses of prOTEINs

15 hours ago   |   Oxford Journals   |   2 articles

AbstractMotivationAlthough structured proteins adopt their lowest free energy conformation in physiological conditions, the individual residues are generally not in their...
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BbeaR: an R package and framework for epitope-specific antibody profiling

15 hours ago   |   Oxford Journals

AbstractSummaryAnalysis of epitope-specific antibody repertoires has provided novel insights into the pathogenesis of inflammatory disorders, especially allergies. A novel...
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Structure and Binding Ability of Self‐assembled α‐Lactalbumin Protein Nanotubular Gels

16 hours ago   |   Wiley

Abstract Partial hydrolysis of whey‐based α‐Lactalbumin with Bacillus licheniformis protease induces the formation of nanotubular structures in the presence of calcium ions by...
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Translational landscape and protein biogenesis demands of the early secretory pathway in Komagataella phaffii

20 hours ago   |   Microbial Cell Factories

Eukaryotes use distinct networks of biogenesis factors to synthesize, fold, monitor, traffic, and secrete proteins. During heterologous expression, saturation of any of these...
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Inactivation of ICAM1 inhibits metastasis and improves the prognosis of Ewing's sarcoma

22 hours ago   |   Springer

Abstract Background Ewing's sarcoma is a kind of malignant tumor, which often occurs in the long bone, pelvis, and other bone tissues, as well as some soft tissues. It often...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Latin America Expansion

Latin America Expansion

We're growing! At PSC Biotech Corporation, we take great pleasure in announcing that, in light of our remarkable continuous growth over the last several years, we are expanding... Read more ...

Case Study | How Thermo Fisher Scientific Streamlined Inspection Management...

Case Study | How Thermo Fisher Scientific Streamlined Inspection Management With AuditUtopia®

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How to Find Mutated Sperm? Just Go FISH

How to Find Mutated Sperm? Just Go FISH

Chemotherapy and radiation treatments are known to cause harsh side effects that patients can see or feel throughout their bodies. Yet there are additional, unseen and often... Read more ...

Performance Improvement of Near-Infrared Spectroscopy-based Brain-Computer...

Transcranial near-infrared photobiomodulation can modulate physiological characteristics of the human brain, such as the cerebral blood flow and oxidative metabolism. Here, we... Read more ...

Non-invasive Ring Electrode with a Wireless Electrical Recording and...

Preterm labor and birth are the primary causes of neonatal morbidities and mortalities. The early detection and treatment of preterm uterine muscular contraction are crucial... Read more ...

Improved High-density Myoelectric Pattern Recognition Control Against...

The objective of this work is to develop a robust method for myoelectric control towards alleviating the in-terference of electrode shift. Methods: In the proposed method, a... Read more ...

Task-space Synergies for Reaching using Upper-limb Prostheses

Synergistic prostheses enable the coordinated movement of the human-prosthetic arm, as required by activities of daily living. This is achieved by coupling the motion of the... Read more ...

Speed adaptable prosthetic foot; concept description, prototyping and...

This paper presents a novel design of a prosthetic foot that features adaptable stiffness that changes according to the speed of ankle motion. The motivation is the natural... Read more ...

Deep Learning Architecture to Assist with Steering a Powered Wheelchair

This paper describes a novel Deep Learning architecture to assist with steering a powered wheelchair. A rule-based approach is utilized to train and test a Long Short Term... Read more ...

Promoting Functional and Independent Sitting in Children with Cerebral Palsy...

Seated postural abilities are critical to functional independence and participation in children with cerebral palsy, Gross Motor Functional Classification System levels III-IV... Read more ...