Protein
Enteric infection induces Lark-mediated intron retention at the 5′ end of Drosophila genes
1 day ago | Genome Biology | 2 articles
RNA splicing is a key post-transcriptional mechanism that generates protein diversity and contributes to the fine-tuning of gene expression, which may facilitate adaptation to...
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Revolution Medicines Maps Out an IPO to Reach Cancer's Frontiers
2 days ago | Xconomy
Cancer research has revealed proteins known to play a role in the disease, but with no known way of stopping what they do. In pharmaceutical parlance, they're “undruggable.”...
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Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering
2 days ago | ACS Division of Biological Chemistry | 8 articles
Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0445-9 A chemoproteomics and protein engineering strategy to investigate metabolic activity...
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A fungal family of lytic polysaccharide monooxygenase-like copper proteins
2 days ago | ACS Division of Biological Chemistry | 8 articles
Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0438-8 The X325 protein family is highly similar to lytic polysaccharide monooxygenases in...
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A lytic polysaccharide monooxygenase-like protein functions in fungal copper import and meningitis
2 days ago | ACS Division of Biological Chemistry | 8 articles
Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0437-9 In the fungal pathogen Cryptococcus neoformans, Bim1 is a copper-binding lytic...
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Development of Small‐Scale Models to Understand the Impact of Continuous Downstream Bioprocessing on Integrated Virus Filtration
2 days ago | Wiley
Abstract
We designed small‐scale virus filtration models to investigate the impact of the extended process times and dynamic product streams present in continuous...
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Balancing the double‐edged sword effect of increased resistant starch content and its impact on rice texture: Its genetics and molecular physiological mechanisms
2 days ago | Wiley
Abstract
Resistant starch is the portion of starch that escapes gastrointestinal digestion and acts as a substrate for fermentation of probiotic bacteria in the gut. Aside from...
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Construction and characterization of a high-quality cDNA library of Cymbidium faberi suitable for yeast one- and two-hybrid assays
3 days ago | BMC Biotechnology
Cymbidium faberi is one of the oldest cultivars of oriental orchids, with an elegant flower fragrance. In order to investigate the molecular mechanism and the functions of...
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Why can't Bertrand Might cry? Scientists offer an answer: missing water channels
3 days ago | San Diego Biotechnology
Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that cells from children with NGLY1 deficiency-a rare disorder first described in 2012-lack...
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Cells protect themselves against stress by keeping together
3 days ago | ScienceDaily
For the first time, research shows that the contacts between cells, known as cell adhesion, are essential for cells to survive stress. The findings also suggest that impaired...
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World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
2nd International Conference on Tissue Science and Regenerative Medicine
This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...
Interfacial molecular interactions of cellobiohydrolase Cel7A and its...
Molecular-scale mechanisms of the enzymatic breakdown of cellulosic biomass into fermentable sugars are still poorly understood, with a need for independent measurements of... Read more ...
Brassinosteroid overproduction improves lignocellulose quantity and quality...
As a leading biomass feedstock, poplar plants provide enormous lignocellulose resource convertible for biofuels and bio-chemicals. However, lignocellulose recalcitrance... Read more ...
US biofuel production and policy: implications for land use changes in...
It has been argued that the US biofuel policy is responsible for the land use changes in Malaysia and Indonesia. In this paper, following a short literature review that... Read more ...
Programmable nests for cells
Using DNA, smallest silica particles, and carbon nanotubes, researchers developed novel programmable materials. These nanocomposites can be tailored to various applications and... Read more ...
AveXis Inc.: Research Associate III
AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...
Mirati Therapeutics: Student Assistant
Mirati Therapeutics: Mirati Therapeutics is a targeted oncology company developing an advanced pipeline of breakthrough medicines for precisely defined patient populations San... Read more ...
Inhibition of lignification of Zizania latifolia with radio frequency...
Zizania latifolia is easily lignified after harvesting, leading to the degradation of food quality and commercial value. Thus, this study evaluated the effect of radio... Read more ...
Performance difference of graph-based and alignment-based hybrid error...
The error-prone third-generation sequencing long reads can be corrected by the high-quality second-generation sequencing short reads, which is referred to as hybrid error... Read more ...
CHROMATIX: computing the functional landscape of many-body chromatin...
Chromatin interactions are important for gene regulation and cellular specialization. Emerging evidence suggests many-body spatial interactions play important roles in... Read more ...
Bachem: Validation Engineer II, QA
Bachem: Your Responsibilities The Validation Engineer II fulfills a critical role in GMP operations. This individual must plan and execute validation studies, Vista, CA, US ... Read more ...