Protein

FINDER: an automated software package to annotate eukaryotic genes from RNA-Seq data and associated protein sequences

3 hours ago   |   BMC Bioinformatics

Gene annotation in eukaryotes is a non-trivial task that requires meticulous analysis of accumulated transcript data. Challenges include transcriptionally active regions of the...
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Scientist/Senior Scientist - Protein Sequencing Assay Platform Development - Encodia, Inc. - San Diego, CA

4 hours ago   |   San Diego Biotechnology   |   8 articles

The ideal candidate will have a strong quantitative analytical skill set and deep expertise in designing, developing, optimizing and troubleshooting high-plex...From Encodia...
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'Undruggable' cancer protein becomes druggable, thanks to shrub

10 hours ago   |   ScienceDaily

A chemist has found a way to synthesize a compound to fight a previously 'undruggable' cancer protein with benefits across a myriad of cancer types.
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Supplement treats schizophrenia in mice, restores healthy 'dance' and structure of neurons

19 hours ago   |   ScienceDaily

A simple dietary supplement reduces behavioral symptoms in mice with a genetic mutation that causes schizophrenia. After additional experiments, including visualizing the...
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Scientist II - NMR - Takeda Pharmaceuticals - San Diego, CA

20 hours ago   |   San Diego Biotechnology   |   16 articles

DDS is a multidisciplinary team aimed at exploring and building new technologies in emergent areas of drug discovery - from targeted protein degradation to...From Takeda...
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LC/MS Protein Characterization Scientist - Eurofins - San Diego, CA

21 hours ago   |   San Diego Biotechnology   |   16 articles

Familiar with protein structure and chemistry; experience handling proteins in a laboratory setting. Develop LCMS method for peptide mapping and disulfide...From Eurofins...
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A Novel Design of Multi-epitope Vaccine Against Helicobacter pylori by Immunoinformatics Approach

23 hours ago   |   Springer

Abstract Helicobacter pylori is a gram-negative spiral bacterium that caused infections in half of the world's population and had been identified as type I carcinogen by the...
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Evaluation of Physicochemical Activity of Anticancer Fusion Proteins; Enterocin A- R type pyocin-Lactocin-Ligand Against Gastric Cancer Cell Line by Real-Time RT PCR Technique

23 hours ago   |   Springer

Abstract Gastric cancer treatment remains a major challenge. There are many reports on the positive efficacy of Bacteriocins associated with anti-cancer sequences. The main...
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Subtractive Proteomics and Reverse Vaccinology Strategies for Designing a Multiepitope Vaccine Targeting Membrane Proteins of Klebsiella pneumoniae

23 hours ago   |   Springer   |   2 articles

Abstract Klebsiella pneumoniae is a Gram-negative opportunistic pathogen that causes bacteremia, meningitis, endocarditis, cellulitis, urinary tract infections. The emergence...
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LC/MS Protein Characterization Scientist - Eurofins Central Laboratory - San Diego, CA

1 day ago   |   San Diego Biotechnology   |   7 articles

Familiar with protein structure and chemistry; experience handling proteins in a laboratory setting. Develop LCMS method for peptide mapping and disulfide...From Eurofins...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Roche culls two COVID drug hopefuls amid Q1 clear-out

Roche culls two COVID drug hopefuls amid Q1 clear-out badams Wed, 04/21/2021 - 03:27 Read more ...

AstraZeneca cancer R&D exec Charles Ferté hits the exit

AstraZeneca cancer R&D exec Charles Ferté hits the exit badams Wed, 04/21/2021 - 03:46 Read more ...

FINDER: an automated software package to annotate eukaryotic genes from...

Gene annotation in eukaryotes is a non-trivial task that requires meticulous analysis of accumulated transcript data. Challenges include transcriptionally active regions of the... Read more ...

AutoDTI++: deep unsupervised learning for DTI prediction by autoencoders

Drug-target interaction plays a vital role in drug discovery. Identifying drug-target interactions related to wet-lab experiments are costly, laborious, and time-consuming... Read more ...

Constructing and analysing dynamic models with modelbase v1.2.3: a software...

Computational mathematical models of biological and biomedical systems have been successfully applied to advance our understanding of various regulatory processes, metabolic... Read more ...

MAPS: machine-assisted phenotype scoring enables rapid functional assessment...

Genetic testing is widely used in evaluating a patient's predisposition to hereditary diseases. In the case of cancer, when a functionally impactful mutation is identified in a... Read more ...

A flexible ChIP-sequencing simulation toolkit

A major challenge in evaluating quantitative ChIP-seq analyses, such as peak calling and differential binding, is a lack of reliable ground truth data. Accurate simulation of... Read more ...

ScMET: Bayesian modeling of DNA methylation heterogeneity at single-cell...

High-throughput single-cell measurements of DNA methylomes can quantify methylation heterogeneity and uncover its role in gene regulation. However, technical limitations and... Read more ...

Genomic insights into the origin, domestication and genetic basis of...

Castor bean is an important oil crop, which belongs to the Euphorbiaceae family. The seed oil of castor bean is currently the only commercial source of ricinoleic acid that can... Read more ...

Molecular mechanism underlying the effect of maleic hydrazide treatment on...

Duckweed is considered a promising feedstock for bioethanol production due to its high biomass and starch production. The starch content can be promoted by plant growth... Read more ...