Protein

The majority of A-to-I RNA editing is not required for mammalian homeostasis

3 hours ago   |   Springer

Abstract Background Adenosine-to-inosine RNA editing, mediated by ADAR1 and ADAR2, occurs at tens of thousands to millions of sites across mammalian transcriptomes. A-to-I...
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Faint gray bands in Drosophila melanogaster polytene chromosomes are formed by coding sequences of housekeeping genes

5 hours ago   |   Springer

Abstract In Drosophila melanogaster , the chromatin of interphase polytene chromosomes appears as alternating decondensed interbands and dense black or thin gray bands...
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Analyzing the action of evolutionarily conserved modules on HMW-GS 1Ax1 promoter activity

7 hours ago   |   Springer

Abstract Key message The specific and high-level expression of 1Ax1 is determined by different promoter regions. HMW-GS synthesis occurs in aleurone layer cells. Heterologous...
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Construction and Characterization of UBC4 Mutants with Single Residues Swapped from UBC5

8 hours ago   |   Springer

Abstract Ubiquitination is tightly regulated to control degradation, localization and function of various proteins. Ubiquitination is catalysed by three enzymes, namely E1, E2...
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Bidirectional histone-gene promoters in Aspergillus: characterization and application for multi-gene expression

12 hours ago   |   Springer

Abstract Background Filamentous fungi are important producers of enzymes and bioactive secondary metabolites and are exploited for industrial purposes. Expression and...
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Computational design of G Protein-Coupled Receptor allosteric signal transductions

1 day ago   |   ACS Division of Biological Chemistry   |   4 articles

Nature Chemical Biology, Published online: 02 December 2019; doi:10.1038/s41589-019-0407-2 A computational approach for designing GPCRs with new signaling functions including...
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MiR-29b inhibits non-small cell lung cancer progression by targeting STRN4

1 day ago   |   Springer

Abstract Non-small cell lung cancer is a malignant tumor with a high fatality, low overall cure, and survival rates worldwide. When only palliative therapy is available, the...
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Eli Lilly and Company: Biologist-Protein Mass Spectrometry

2 days ago   |   San Diego Biotechnology

Eli Lilly and Company: At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indiana San...
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CytoMegaloVirus Infection Database: A Public Omics Database for Systematic and Comparable Information of CMV

2 days ago   |   Springer

Abstract CytoMegaloVirus is known to cause infection in humans and may remain dormant throughout the life span of an individual. CMV infection has been reported to be fatal in...
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WEDeepT3: predicting type III secreted effectors based on word embedding and deep learning

2 days ago   |   Springer

Abstract Background The type III secreted effectors are one of the indispensable proteins in the growth and reproduction of Gram-negative bacteria. In particular, the...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

IAmScience Mannie Liscum

IAmScience Mannie Liscum

For Mannie Liscum, thinking is a privilege, and his job gives him the chance to be fascinated by human's capacity to conceptualize and learn new things. “It's my goal to use as... Read more ...

New Sanofi CEO Hudson adds next-gen cancer drug tech to the R&D quest...

When Paul Hudson lays out his R&D vision for Sanofi tomorrow, he will have a new slate of interleukin therapies and a synthetic biology platform to boast about. The French... Read more ...

AveXis Inc.: Senior Scientific Training Specialist - cGMP Gene Therapy

AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...

Process Engineer I - Genentech - Oceanside, CA

Focus will be on one or more areas such as design, implementation and/or start-up of new and/or existing facilities with respect to process and/or clean utility...From... Read more ...

Pineoblastoma segregates into molecular sub-groups with distinct...

Abstract Pineoblastomas are rare, aggressive pediatric brain tumors of the pineal gland with modest overall survival despite intensive therapy. We sought to define the clinical... Read more ...

The majority of A-to-I RNA editing is not required for mammalian homeostasis

Abstract Background Adenosine-to-inosine RNA editing, mediated by ADAR1 and ADAR2, occurs at tens of thousands to millions of sites across mammalian transcriptomes. A-to-I... Read more ...

CRISPR System: A High-throughput Toolbox for Research and Treatment of...

Abstract In recent years, the innovation of gene-editing tools such as the CRISPR/Cas9 system improves the translational gap of treatments mediated by gene therapy. The... Read more ...

Exploration of cryptic organic photosensitive compound as Zincphyrin IV in...

Abstract Zincphyrin IV is a potential organic photosensitizer which is of significant interest for applications in biomedicine, materials science, agriculture , and chemistry... Read more ...

Three transcriptional regulators positively regulate the biosynthesis of...

Abstract Polycyclic tetramate macrolactams are a widely distributed class of structurally complex natural products, and most of them exhibit multiple biological activities... Read more ...

Faint gray bands in Drosophila melanogaster polytene chromosomes are formed...

Abstract In Drosophila melanogaster , the chromatin of interphase polytene chromosomes appears as alternating decondensed interbands and dense black or thin gray bands... Read more ...