Metabolic engineering

Efficient production of myo-inositol in Escherichia coli through metabolic engineering

1 day ago   |   Microbial Cell Factories

The biosynthesis of high value-added compounds using metabolically engineered strains has received wide attention in recent years. Myo-inositol , an important compound in the...
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Homology-dependent recombination of large synthetic pathways into E. coli genome via λ-Red and CRISPR/Cas9 dependent selection methodology

2 days ago   |   Microbial Cell Factories

Metabolic engineering frequently needs genomic integration of many heterologous genes for biosynthetic pathway assembly. Despite great progresses in genome editing for the...
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Metabolic engineering of a fast-growing cyanobacterium Synechococcus elongatus PCC 11801 for photoautotrophic production of succinic acid

8 days ago   |   Biotechnology for Biofuels

Cyanobacteria, a group of photosynthetic prokaryotes, are being increasingly explored for direct conversion of carbon dioxide to useful chemicals. However, efforts to engineer...
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Zeaxanthin‐rich Tomato Fruit Developed Through Genetic Manipulations of Carotenoid Biosynthesis

27 days ago   |   ISAAA

Researchers from The Hebrew University of Jerusalem developed zeaxanthin-rich tomato fruit using transgenic metabolic engineering and conventional breeding techniques...
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Dual graph convolutional neural network for predicting chemical networks

1 month ago   |   BMC Bioinformatics

Predicting of chemical compounds is one of the fundamental tasks in bioinformatics and chemoinformatics, because it contributes to various applications in metabolic engineering...
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Development of zeaxanthin‐rich tomato fruit through genetic manipulations of carotenoid biosynthesis

1 month ago   |   Wiley

Abstract The oxygenated carotenoid zeaxanthin provides numerous benefits to human health due to its antioxidant properties. Especially it is linked to protecting, together with...
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Chemical Production from Methanol Using Natural and Synthetic Methylotrophs

1 month ago   |   Wiley

Methanol as a chemical feedstock is becoming increasingly important as it is derived from natural gas and is a feasible end‐product for captured carbon dioxide. Biological...
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Biotechnological Production of Flavonoids: An Update on Plant Metabolic Engineering, Microbial Host Selection and Genetically Encoded Biosensors

1 month ago   |   Wiley

Flavonoids represent a diversified family of phenylpropanoid‐derived plant secondary metabolites. They are widely found in fruits, vegetables and medicinal herbs and plants...
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Improving cytosolic aspartate biosynthesis increases glucoamylase production in Aspergillus niger under oxygen limitation

1 month ago   |   Microbial Cell Factories

Glucoamylase is one of the most industrially applied enzymes, produced by Aspergillus species, like Aspergillus niger. Compared to the traditional ways of process optimization...
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Microbial engineering for production of N‐functionalized amino acids and amines

2 monthes ago   |   Wiley

Abstract N‐Functionalized amines play important roles in nature and occur, for example, in the antibiotic vancomycin, the immunosuppressant cyclosporine, the cytostatic...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Merck Outlines COVID-19 Ambitions With Buyout Deal, Collaborations

Merck Outlines COVID-19 Ambitions With Buyout Deal, Collaborations

Merck exited the holiday weekend with some fireworks of its own, announcing three major programs on Tuesday all related to investments in finding ways to treat and prevent... Read more ...

Insitro Adds $143M to Fuel Machine Learning-Driven Drug Development

Insitro Adds $143M to Fuel Machine Learning-Driven Drug Development

A stem cell biologist, a gene editing expert, and a data engineer walk into a room...and that's just a few of the people Daphne Koller has recruited in the past two years to... Read more ...

Site of LUX-ZEPLIN Dark Matter Search Project Carefully Ramps Up Science Work

Site of LUX-ZEPLIN Dark Matter Search Project Carefully Ramps Up Science Work

A photomultiplier tube array that is part of the LUX-ZEPLIN experiment at the Sanford Underground Research Facility in Lead, South Dakota. The photomultiplier tubes are... Read more ...

Viacyte Adds $27M to Move Ahead Trio of Stem Cell Diabetes Treatments

Viacyte Adds $27M to Move Ahead Trio of Stem Cell Diabetes Treatments

Privately held biotech ViaCyte has banked $27 million, the majority an installment of cash from a tranched $80 million Series D financing round it closed in late 2018. The... Read more ...

COVID-19 Sparks New Opportunities for Digital Health Companies

COVID-19 Sparks New Opportunities for Digital Health Companies

Clinicians and regulators are rethinking how healthcare is provided amid precautions prompted by COVID-19. In-person physician visits don't fit within the physical distancing... Read more ...

Bristol Myers Squibb Company: Associate Director of San Diego Global Capital...

Bristol Myers Squibb Company: Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused... Read more ...

Sorrento Receives FDA IND Clearance to Initiate a Phase I Clinical Trial of...

SAN DIEGO, May 26, 2020 - Sorrento Therapeutics, Inc. today announced it has received clearance from the U.S. Food and Drug Administration for its investigational new drug... Read more ...

Public Disclosure of COVID-19 Cases Is More Effective than Lockdowns

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Gerald Joyce elected to Royal Swedish Academy of Sciences

LA JOLLA-Salk Professor Gerald Joyce, a pioneer in the field of in vitro evolution, has been elected to the prestigious Royal Swedish Academy of Sciences as a foreign member... Read more ...

Sugars that coat proteins are a possible drug target for pancreatitis

LA JOLLA-Pancreatitis is an inflammation of the pancreas that accounts for 275,000 hospitalizations in the United States annually. Patients who suffer from hereditary... Read more ...