Melanoma

Prebiotics help mice fight melanoma by activating anti-tumor immunity

13 days ago   |   San Diego Biotechnology

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that two prebiotics, mucin and inulin, slowed the growth of melanoma in mice by boosting the immune...
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Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair

13 days ago   |   Journal of Biosciences   |   2 articles

Abstract GAGA associated factor is a sequence-specific DNA binding transcription factor that is evolutionarily conserved from flies to humans. Emerging evidence shows a...
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Immuno-oncology combination for melanoma using Nektar drug boosts cell therapy in mice

23 days ago   |   Fierce Biotech

In mouse models of melanoma, combining infusions of cancer-killing T cells with Nektar's experimental immunotherapy drug bempegaldesleukin produced an increased number of T...
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Gold nanoparticle based double-labeling of melanoma extracellular vesicles to determine the specificity of uptake by cells and preferential accumulation in small metastatic lung tumors

1 month ago   |   Journal of Nanobiotechnology

Extracellular vesicles have shown great potential for targeted therapy, as they have a natural ability to pass through biological barriers and, depending on their origin, can...
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Cancer Drug Developer BioNTech to Buy Neon Therapeutics in $67M Deal

Cancer Drug Developer BioNTech to Buy Neon Therapeutics in $67M Deal

1 month ago   |   Xconomy

Neon Therapeutics closed 2019 by curtailing its cancer vaccine programs and laying off 24 percent of its workforce, part of a corporate restructuring aimed at finding a new...
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Study reveals a new approach to enhancing response to immunotherapy in melanoma

1 month ago   |   San Diego Biotechnology   |   2 articles

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a new way to boost the immune system's ability to fight cancer. The study, which was performed...
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A new strategy for boosting PD-1 blockers in melanoma

1 month ago   |   Fierce Biotech

In melanoma, at least half of patients don't respond to PD-1 blockers like Bristol-Myer Squibb's Opdivo and Merck's Keytruda. Sanford Burnham researchers are proposing a new...
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Robotic-Assisted Pelvic Lymphadenectomy for Metastatic Melanoma Results in Durable Oncologic Outcomes

2 monthes ago   |   Springer

Abstract Background Robotic pelvic lymphadenectomy has been demonstrated to be a safe and effective minimally invasive approach for patients with metastatic melanoma to the...
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The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study

2 monthes ago   |   Springer

Abstract Background Evidence pointing to a synergistic effect of stereotactic radiosurgery with concurrent immunotherapy or targeted therapy in patients with melanoma brain...
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Joint detection of germline and somatic copy number events in matched tumor-normal sample pairs

2 monthes ago   |   Oxford Journals

AbstractMotivationWhole-genome sequencing of tumor-normal sample pairs is a powerful approach for comprehensively characterizing germline copy number variations and somatic...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Invetx Fetches $15M to Develop Biologic Drugs for Man's Best Friend

Invetx Fetches $15M to Develop Biologic Drugs for Man's Best Friend

Veterinarians have a saying that a cat is not a small dog, says Invetx CEO Juergen Horn. Obviously, a dog of any size isn't the same as a human. But Horn, a veterinarian, says... Read more ...

Lundbeck's Alder Bio Bet Pays Off With FDA Approval of Migraine Drug

Lundbeck's Alder Bio Bet Pays Off With FDA Approval of Migraine Drug

A migraine drug that Lundbeck added to its pipeline via its nearly $2 billion acquisition of Alder BioPharmaceuticals won FDA approval on Friday. The drug, eptinezumab , is... Read more ...

IAmScience George Stewart

IAmScience George Stewart

By Becca Wolf | Bond LSC Medical bacteriologist, George Stewart has had a few stops along the way before he got to Bond LSC in 2004. Having done schooling and research at... Read more ...

Arima Genomics Completes Series A Financing

SAN DIEGO--Arima Genomics, Inc., a company focused on research tools to accelerate the understanding of genome sequence and structure toward their role in human health and... Read more ...

Viking Therapeutics to Participate in Upcoming Investor Conferences

SAN DIEGO, Feb. 24, 2020 /PRNewswire/ - Viking Therapeutics, Inc. , a clinical-stage biopharmaceutical company focused on the development of novel therapies for metabolic and... Read more ...

Molecular characterization and overexpression analyses of secologanin...

Abstract Camptothecin is a high-value anti-cancerous compound produced in many taxonomically unrelated species. Its biosynthesis involves a complex network of pathways and a... Read more ...

Modulation of the Purine Pathway for Riboflavin Production in Flavinogenic...

Riboflavin is an indispensable nutrient for humans and animals, since it is the precursor of the essential coenzymes FMN and FAD, involved in variety of metabolic reactions... Read more ...

A Critical Review of Genome Editing and Synthetic Biology Applications in...

Being the green gold of the future, microalgae and cyanobacteria have recently attracted considerable interest worldwide, for they can be used to produce different kinds of... Read more ...

Biodegradation of penicillin G from industrial bacteria residue by...

An efficient biodegradation-strengthening approach was developed to improve penicillin G degradation from industrial bacterial residue in an expanded bed adsorption bioreactor... Read more ...

More clues for how the monkeyflower got its spots

The monkeyflower, or Mimulus, though possessing a relatively simple genome is able to produce a stunning array of pigmentation patterns. A team of researchers is one step... Read more ...