Lymphoma

Scripps Research's Calibr to Test “Switchable” CAR-T in Clinical Trial

Scripps Research's Calibr to Test “Switchable” CAR-T in Clinical Trial

17 days ago   |   Xconomy

Scripps Research is charting new territory with its Calibr division, a drug discovery and drug development group within the research institute that is advancing its own...
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Epizyme's Soft Tissue Cancer Drug Granted Speedy FDA Approval

Epizyme's Soft Tissue Cancer Drug Granted Speedy FDA Approval

1 month ago   |   Xconomy

Epizyme won accelerated FDA approval Thursday for a drug developed to treat the rare cancer epithelioid sarcoma. The regulatory decision for the Epizyme drug, tazemetostat...
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MiRagen Therapeutics to Present New Cobomarsen Clinical Trial Data for Adult T-Cell Leukemia/Lymphoma at Two Upcoming Conferences

1 month ago   |   San Diego Biotechnology

BOULDER, Colo., Jan. 23, 2020 - miRagen Therapeutics, Inc. , a clinical-stage biopharmaceutical company developing proprietary RNA-targeted therapies with a specific focus on...
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Bio Roundup: EQRx's Ambitions, Nektar No Vote, New Frazier Fund & More

Bio Roundup: EQRx's Ambitions, Nektar No Vote, New Frazier Fund & More

1 month ago   |   Xconomy

Perhaps the most talked-about news at the JP Morgan Healthcare Conference this week was a new startup that launched with $200 million and an ambitious claim its first drug...
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Incyte Commits $900M to MorphoSys for Rights to Lymphoma Drug

Incyte Commits $900M to MorphoSys for Rights to Lymphoma Drug

1 month ago   |   Xconomy

Two weeks after MorphoSys filed for FDA review of its experimental treatment for a form of lymphoma, the company has struck a deal with Incyte to further develop and...
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Incyte pays $750M upfront for rights to MorphoSys cancer drug

1 month ago   |   Fierce Biotech

Incyte is set to pay MorphoSys $750 million upfront for rights to anti-CD19 antibody tafasitamab. The licensing deal, which features a $150 million equity investment and up to...
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Co-expression Networks Identify DHX15 RNA Helicase as a B Cell Regulatory Factor

1 month ago   |   San Diego Biotechnology

Novel immuno-networks revealed by an Artificial Intelligence approach developed at SBP Analysis of lymphoma RNA data predicted causal relationships between the DEAH-box RNA...
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HTLV-1 contains a high CG dinucleotide content and is susceptible to the host antiviral protein ZAP

2 monthes ago   |   Springer

Abstract Background Human T cell leukaemia virus type 1 is a retrovirus associated with human diseases such as adult T-cell leukaemia/lymphoma and HTLV-1 associated...
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Chrysophanol suppresses growth and metastasis of T cell acute lymphoblastic leukemia via miR-9/PD-L1 axis

2 monthes ago   |   Springer

Abstract T cell acute lymphoblastic leukemia was a malignant lymphoma. Therefore, the development of novel therapeutic agents against T-ALL is imperative. Previous studies have...
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Design and synthesis of novel spirooxindole-indenoquinoxaline derivatives as novel tryptophanyl-tRNA synthetase inhibitors

2 monthes ago   |   Springer

Abstract In the current study, we used an integrated approach combining bioinformatics, rational drug design, one-pot synthesis, and biological experiments in vitro for the...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Invetx Fetches $15M to Develop Biologic Drugs for Man's Best Friend

Invetx Fetches $15M to Develop Biologic Drugs for Man's Best Friend

Veterinarians have a saying that a cat is not a small dog, says Invetx CEO Juergen Horn. Obviously, a dog of any size isn't the same as a human. But Horn, a veterinarian, says... Read more ...

Lundbeck's Alder Bio Bet Pays Off With FDA Approval of Migraine Drug

Lundbeck's Alder Bio Bet Pays Off With FDA Approval of Migraine Drug

A migraine drug that Lundbeck added to its pipeline via its nearly $2 billion acquisition of Alder BioPharmaceuticals won FDA approval on Friday. The drug, eptinezumab , is... Read more ...

Arima Genomics Completes Series A Financing

SAN DIEGO--Arima Genomics, Inc., a company focused on research tools to accelerate the understanding of genome sequence and structure toward their role in human health and... Read more ...

Viking Therapeutics to Participate in Upcoming Investor Conferences

SAN DIEGO, Feb. 24, 2020 /PRNewswire/ - Viking Therapeutics, Inc. , a clinical-stage biopharmaceutical company focused on the development of novel therapies for metabolic and... Read more ...

Molecular characterization and overexpression analyses of secologanin...

Abstract Camptothecin is a high-value anti-cancerous compound produced in many taxonomically unrelated species. Its biosynthesis involves a complex network of pathways and a... Read more ...

Modulation of the Purine Pathway for Riboflavin Production in Flavinogenic...

Riboflavin is an indispensable nutrient for humans and animals, since it is the precursor of the essential coenzymes FMN and FAD, involved in variety of metabolic reactions... Read more ...

A Critical Review of Genome Editing and Synthetic Biology Applications in...

Being the green gold of the future, microalgae and cyanobacteria have recently attracted considerable interest worldwide, for they can be used to produce different kinds of... Read more ...

Biodegradation of penicillin G from industrial bacteria residue by...

An efficient biodegradation-strengthening approach was developed to improve penicillin G degradation from industrial bacterial residue in an expanded bed adsorption bioreactor... Read more ...

More clues for how the monkeyflower got its spots

The monkeyflower, or Mimulus, though possessing a relatively simple genome is able to produce a stunning array of pigmentation patterns. A team of researchers is one step... Read more ...

A deep dive into cellular aging

Scientists have discovered that mitochondria trigger senescence, the sleep-like state of aged cells, through communication with the cell's nucleus -a nd identified an... Read more ...