Genomics

LongAGE: defining breakpoints of genomic structural variants through optimal and memory efficient alignments of long reads

1 day ago   |   Oxford Journals

AbstractSummaryDefining the precise location of structural variations at single-nucleotide breakpoint resolution is a challenging problem due to large gaps in alignment...
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A Public Website for the Automated Assessment and Validation of SARS-CoV-2 Diagnostic PCR Assays

1 day ago   |   Oxford Journals

AbstractSummaryPolymerase chain reaction-based assays are the current gold standard for detecting and diagnosing SARS-CoV-2. However, as SARS-CoV-2 mutates, we need to...
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VIDHOP, viral host prediction with Deep Learning

1 day ago   |   Oxford Journals

AbstractMotivationZoonosis, the natural transmission of infections from animals to humans, is a far-reaching global problem. The recent outbreaks of Zikavirus, Ebolavirus, and...
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Helix moves a step closer to goal of 100,000 daily COVID-19 tests at San Diego lab

1 day ago   |   San Diego Biotechnology

Company gets FDA clearance for coronavirus tests based on next-generation genomics sequencing...
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Creative block of molecular evolution: Adaptive mutations repeat themselves in tiny crustaceans of Lake Baikal

2 days ago   |   Phys

A group of scientists from Skoltech and the Institute for Information Transmission Problems of RAS showed, using Lake Baikal amphipods as an example, that parallel evolution...
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New research reveals previously hidden features of plant genomes

2 days ago   |   Phys

An international team led by the Plant Phenotyping and Imaging Research Centre at the University of Saskatchewan and researchers at Agriculture and Agri-Food Canada has decoded...
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CRISPR-Cas9 Genome Editing Tool for the Production of Industrial Biopharmaceuticals

2 days ago   |   Springer

Abstract A broad range of cell lines with characteristic features are used as bio-factories to produce recombinant proteins for basic research and therapeutic purposes. Genetic...
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Discovery and Characterization of a Novel Thermostable β‐Amino Acid Transaminase from a Meiothermus Strain Isolated in an Icelandic Hot Spring

2 days ago   |   Wiley

Abstract A Meiothermus strain capable of using β‐phenylalanine for growth was isolated by culture enrichment of samples collected in hot environments and the genome was...
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Research Assistant I (Conrad Prebys Center for Chemical Genomics) - Sanford Burnham Prebys Medical Discovery Institute - La Jolla, CA

4 days ago   |   San Diego Biotechnology

Strong attention to detail and commitment to precision is preferred. Previous experience in a biotech or pharmaceutical setting is a plus.From Sanford Burnham Prebys Medical...
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Activation and enhancement of caerulomycin A biosynthesis in marine-derived Actinoalloteichus sp. AHMU CJ021 by combinatorial genome mining strategies

5 days ago   |   Microbial Cell Factories

Activation of silent biosynthetic gene clusters in marine-derived actinomycete strains is a feasible strategy to discover bioactive natural products. Actinoalloteichus sp. AHMU...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Pfizer's Bourla: There's Coronavirus Vaccine Pressure, But It's Not Political

Pfizer's Bourla: There's Coronavirus Vaccine Pressure, But It's Not Political

Pfizer Inc. CEO Albert Bourla said he doesn't worry about political pressure to bring potentially the first coronavirus vaccine to market, but can't escape feeling the weight... Read more ...

Ligand to Spend $438M to Add Protein Maker Pfenex to Technology Lineup

Ligand to Spend $438M to Add Protein Maker Pfenex to Technology Lineup

Ligand Pharmaceuticals plans to acquire recombinant protein therapeutics maker Pfenex for $438 million, the companies announced Monday. The larger company agreed to pay $12 per... Read more ...

Bayer Boosts Women's Health Drug Pipeline, Paying $425M for KaNDy

Bayer Boosts Women's Health Drug Pipeline, Paying $425M for KaNDy

Bayer has been building up its women's health drug pipeline by striking deals and on Tuesday the pharmaceutical giant unveiled its latest one : $425 million up front for KaNDy... Read more ...

In precisionFDA Challenge, PacBio HiFi Reads Outperform Both Short Reads and...

In precisionFDA Challenge, PacBio HiFi Reads Outperform Both Short Reads and Noisy Long Reads

Figure 1. PrecisionFDA Truth Challenge V2 Results. Of the single-technology entries, those that use PacBio HiFi reads delivered the highest accuracy in all categories... Read more ...

Keeping Cool Efficiently During Heat Waves

Keeping Cool Efficiently During Heat Waves

Berkeley Lab scientist Iain Walker Heat waves are becoming a more regular occurrence across the country. Iain Walker , Leader of the Residential Building Systems Group at... Read more ...

Roche Gut Disease Drug Produces Mixed Results in Late-Stage Trials

Roche Gut Disease Drug Produces Mixed Results in Late-Stage Trials

Results from four studies within a major Roche-run clinical trials program of an investigational gut disease drug have muddled the antibody's path forward after its performance... Read more ...

International Physicists Join Forces in Hunt for Sterile Neutrinos

International Physicists Join Forces in Hunt for Sterile Neutrinos

These four Daya Bay detectors are submerged in a pool of ultrapure water that helps to shield against naturally occurring radiation. Note: This press release is adapted from... Read more ...

Director, Regulatory Operations - Halozyme Therapeutics, Inc. - San Diego, CA

Keen attention to detail with the highest quality standards. Document templates, document style guides) in the training of authors of eCTD documents and other...From Halozyme... Read more ...

Part-Time Logistics Coordinator

Job Duties Logistics: -Will require basic lab work such as: aliquoting, dilutions, and lyophilizing -Help set up and pack shipping boxes daily, generating shipping labels... Read more ...

'AeroNabs' promise powerful, inhalable protection against COVID-19

Scientists have devised a novel approach to halting the spread of SARS-CoV-2, the virus that causes COVID-19. The researchers engineered a completely synthetic... Read more ...