Genomics

Gcluster: a simple-to-use tool for visualizing and comparing genome contexts for numerous genomes

1 day ago   |   Oxford Journals

AbstractMotivationComparing the organization of gene, gene clusters, and their flanking genomic contexts is of critical importance to the determination of gene function and...
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DeepMILO: a deep learning approach to predict the impact of non-coding sequence variants on 3D chromatin structure

2 days ago   |   Genome Biology   |   2 articles

Non-coding variants have been shown to be related to disease by alteration of 3D genome structures. We propose a deep learning method, DeepMILO, to predict the effects of...
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Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts

2 days ago   |   Genome Biology

Osteoporosis is a complex disease with a strong genetic contribution. A recently published genome-wide association study for estimated bone mineral density identified 1103...
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CNV-BAC: Copy Number Variation Detection in Bacterial Circular Genome

2 days ago   |   Oxford Journals

AbstractMotivationWhole genome sequencing is widely used for copy number variation detection. However, for most bacteria, their circular genome structure and high replication...
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Genome sequencing and phylogenetic analysis of K1G4: a new Komagataeibacter strain producing bacterial cellulose from different carbon sources

2 days ago   |   Springer

Abstract Objective The objective of this study was to evaluate the ability of a new Komagataeibacter xylinus strain in producing bacterial cellulose from glucose, mannitol and...
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A Cas12a ortholog with stringent PAM recognition followed by low off-target editing rates for genome editing

3 days ago   |   Genome Biology

AsCas12a and LbCas12a nucleases are reported to be promising tools for genome engineering with protospacer adjacent motif TTTV as the optimal. However, the C-containing PAM...
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Missing link in coronavirus jump from bats to humans could be pangolins, not snakes

3 days ago   |   ScienceDaily

As scientists scramble to learn more about the SARS-CoV-2 coronavirus, two recent studies of the virus' genome reached controversial conclusions: namely, that snakes are...
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Scientists can now edit multiple genome fragments at a time

3 days ago   |   ScienceDaily

Scientists have developed CHyMErA, a new CRISPR-based tool for more versatile genome editing applications to help shed light on how multiple genes cooperate in health and disease.
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Clinical Bioinformaticist-Genomics - Rady Children's Hospital-San Diego - San Diego, CA

3 days ago   |   San Diego Biotechnology   |   5 articles

The environment is highly cross-functional, with a rich medical research heritage and multitude of collaborations with the biotech industry, academic...From Rady Children's...
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The origin of genomic N 6 -methyl-deoxyadenosine in mammalian cells

4 days ago   |   ACS Division of Biological Chemistry   |   2 articles

Nature Chemical Biology, Published online: 23 March 2020; doi:10.1038/s41589-020-0504-2 A metabolic labeling method reveals that genomic N6-methyl-deoxyadenosine in mammalian...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Mirati Therapeutics: Vice President, Investor Relations & External Affairs...

Mirati Therapeutics: The Vice President, Investor Relations and External Affairs will be responsible for the development, implementation and management of an... San Diego, CA... Read more ...

16S rRNA Gene-Based Analysis Reveals the Effects of Gestational Diabetes on...

Abstract Hyperglycemia is one of the metabolic characteristics of gestational diabetes mellitus. Considering that GDM is able to cause changes in the gut bacterial community... Read more ...

New gene therapy product Zolgensma to treat spinal muscular atrophy

Posted on: 30 March 2020, The EMA has recommended granting a conditional marketing authorisation in the European Union for the gene therapy Zolgensmato treat babies and young... Read more ...

Modeling ethanol production through gas fermentation: a biothermodynamics...

Ethanol production through fermentation of gas mixtures containing CO, CO2 and H2 has just started operating at commercial scale. However, quantitative schemes for... Read more ...

Use of pretreatments for enhancing clarification efficiency of depth...

ABSTRACT High cell density, high product titer mammalian cell culture is the new paradigm for production of recombinant proteins. While the typical motivation is to get a high... Read more ...

Rigel Pharmaceuticals, Inc.: Territory Business Manager

Rigel Pharmaceuticals, Inc.: - This is a field based position covering San Diego, South Eastern portion of California and Las Vegas POSITION SUMMARY: Rigel Territory... Read more ...

AveXis Inc.: Research and Development Professionals

AveXis Inc.: OverviewWe're Growing and looking for talented Research professionals!Ready to join a team committed to moving gene therapies into the clinical and co San Diego... Read more ...

Mirati Therapeutics: Quality Assurance Contractor: 2020-64

Mirati Therapeutics: Mirati is looking for a Quality Assurance Contractor to join its Quality team. The ideal candidate will have prior experience working in a fast -paced San... Read more ...

Bachem: Chemist I

Bachem: Your Responsibilities Note: This position is only for 2nd shift The Chemist function is to develop the peptide manufacture process, manufactur Vista, CA, US ... Read more ...

Bachem: Materials Coordinator I

Bachem: Your Responsibilities The Materials Coordinator handles and controls raw materials including dispensing and sampling operations. Responsible for the s Vista, CA, US ... Read more ...