Genome

VIST - a Variant-Information Search Tool for precision oncology

23 hours ago   |   BMC Bioinformatics

Diagnosis and treatment decisions in cancer increasingly depend on a detailed analysis of the mutational status of a patient's genome. This analysis relies on previously...
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Characterization and mechanism of the effects of Mg-Fe layered double hydroxide nanoparticles on a marine bacterium: new insights from genomic and transcriptional analyses

1 day ago   |   Biotechnology for Biofuels

Layered double hydroxides have received widespread attention for their potential applications in catalysis, polymer nanocomposites, pharmaceuticals, and sensors. Here, the...
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AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design

1 day ago   |   Genome Biology

The CRISPR/Cas system is a highly specific genome editing tool capable of distinguishing alleles differing by even a single base pair. Target sites might carry genetic...
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An enhanced genetic model of colorectal cancer progression history

1 day ago   |   Genome Biology

The classical genetic model of colorectal cancer presents APC mutations as the earliest genomic alterations, followed by KRAS and TP53 mutations. However, the timing and...
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Benchmarking software tools for detecting and quantifying selection in evolve and resequencing studies

1 day ago   |   Genome Biology

The combination of experimental evolution with whole-genome resequencing of pooled individuals, also called evolve and resequence is a powerful approach to study the selection...
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Multiple-kernel learning for genomic data mining and prediction

1 day ago   |   BMC Bioinformatics   |   2 articles

Advances in medical technology have allowed for customized prognosis, diagnosis, and treatment regimens that utilize multiple heterogeneous data sources. Multiple kernel...
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Baerhunter: An R package for the discovery and analysis of expressed non-coding regions in bacterial RNA-seq data

2 days ago   |   Oxford Journals

AbstractSummaryStandard bioinformatics pipelines for the analysis of bacterial transcriptomic data commonly ignore non-coding but functional elements e.g. small RNAs, long...
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At ESHG, SMRT Sequencing Contributed to De Novo Assemblies, Structural Variant Discovery

At ESHG, SMRT Sequencing Contributed to De Novo Assemblies, Structural Variant Discovery

2 days ago   |   Pacific Biosciences

The annual meeting of the European Society of Human Genetics - held last month in the sleek Swedish Exhibition & Congress Center in Gothenburg, Sweden - was a terrific assembly...
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Director, FP&A - Singular Genomics - La Jolla, CA

3 days ago   |   San Diego Biotechnology

*Who We Are* Singular Genomics is an early stage, well-funded biotech company in La Jolla, California. We are inventing at the forefront of genomics, one of...From Indeed...
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Genetic census of the human microbiome

3 days ago   |   ScienceDaily

Scientists have analyzed the genetic repertoire of bacteria in the human mouth and gut. The effort marks the first chapter in efforts to compile a compendium of all genes in...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Robots and Africa: Tech transfer accelerates data collection

Robots and Africa: Tech transfer accelerates data collection

Ke Gao and Sam McInturf reveal Sun Bear to presidents and administrators of UWC and MU. By Mariah Cox | Bond LSC Fourteen days. That's how long it took Sam McInturf and Ke Gao... Read more ...

Pfizer Spinout SpringWorks, Migraine Drug Firm Satsuma Prep IPOs

Pfizer Spinout SpringWorks, Migraine Drug Firm Satsuma Prep IPOs

The dog days of summer are here and IPO activity has slowed, but that hasn't stopped some biotech companies from securing a place in the line leading to Wall Street. Late... Read more ...

AbbVie's Successor to Humira Wins FDA OK for Rheumatoid Arthritis

AbbVie's Successor to Humira Wins FDA OK for Rheumatoid Arthritis

An anti-inflammatory drug that AbbVie has been developing as a successor to adalimumab , the world's top-selling drug, won the regulatory OK Friday as a treatment for... Read more ...

USC and UC San Diego try to move on after painful fight over Alzheimer's...

Both schools say they're found a way to prosper while studying the inscrutable disease... Read more ...

Senior R&D Scientist - Single cell application - Universal Sequencing...

Design and execute experiments, and analyze data independently. Establish product quality control assays for in-process & final product test and deliver well...From Indeed... Read more ...

VIST - a Variant-Information Search Tool for precision oncology

Diagnosis and treatment decisions in cancer increasingly depend on a detailed analysis of the mutational status of a patient's genome. This analysis relies on previously... Read more ...

RF Purify: a novel tool for comprehensive analysis of tumor-purity in...

With the advent of array-based techniques to measure methylation levels in primary tumor samples, systematic investigations of methylomes have widely been performed on a large... Read more ...

Multitask learning for biomedical named entity recognition with...

Biomedical named entity recognition is a fundamental and essential task for biomedical literature mining, which affects the performance of downstream tasks. Most BioNER models... Read more ...

Characterization and mechanism of the effects of Mg-Fe layered double...

Layered double hydroxides have received widespread attention for their potential applications in catalysis, polymer nanocomposites, pharmaceuticals, and sensors. Here, the... Read more ...

Semiparametric estimation in regression with missing covariates using...

Abstract We investigate semiparametric estimation of regression coefficients through generalized estimating equations with single-index models when some covariates are missing... Read more ...