Gene

Maximizing Antibody Production in a Targeted Integration Host by Optimization of Subunit Gene Dosage and Position

5 hours ago   |   Wiley

Abstract Historically, therapeutic protein production in Chinese hamster ovary cells has been accomplished by random integration of expression plasmids into the host cell...
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Mechanism for how common gene therapy vectors enter cells

16 hours ago   |   ScienceDaily

Researchers have identified a novel cellular entry factor for adeno-associated virus vector types - the most commonly used viral vectors for in vivo gene therapy. The...
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Joint reconstruction of multiple gene networks by simultaneously capturing inter-tumor and intra-tumor heterogeneity

22 hours ago   |   Oxford Journals

AbstractMotivationReconstruction of cancer gene networks from gene expression data is important for understanding the mechanisms underlying human cancer. Due to heterogeneity...
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Morbigenous brain region and gene detection with a genetically evolved random neural network cluster approach in late mild cognitive impairment

22 hours ago   |   Oxford Journals

AbstractMotivationThe multimodal data fusion analysis becomes another important field for brain disease detection and increasing researches concentrate on using neural network...
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Generalizable sgRNA design for improved CRISPR/Cas9 editing efficiency

22 hours ago   |   Oxford Journals

AbstractMotivationThe development of CRISPR/Cas9 technology has provided a simple yet powerful system for targeted genome editing. In recent years, this system has been widely...
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Identifying and removing haplotypic duplication in primary genome assemblies

22 hours ago   |   Oxford Journals

AbstractMotivationRapid development in long read sequencing and scaffolding technologies is accelerating the production of reference-quality assemblies for large eukaryotic...
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Transfer index, NetUniFrac and some useful shortest path-based distances for community analysis in sequence similarity networks

22 hours ago   |   Oxford Journals   |   2 articles

AbstractMotivationPhylogenetic trees and the methods for their analysis have played a key role in many evolutionary, ecological and bioinformatics studies. Alternatively...
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Reverse engineering directed gene regulatory networks from transcriptomics and proteomics data of biomining bacterial communities with approximate Bayesian computation and steady-state signalling simulations

1 day ago   |   BMC Bioinformatics

Network inference is an important aim of systems biology. It enables the transformation of OMICs datasets into biological knowledge. It consists of reverse engineering gene...
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Scientists identify gene that puts brakes on tissue growth

1 day ago   |   ScienceDaily

The planarian flatworm is a simple animal with a mighty ability: it can regenerate itself from nearly every imaginable injury, including decapitation. Scientists have studied...
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Drug profiling and gene scissors open new avenues in immunotherapy

1 day ago   |   ScienceDaily

Researchers have discovered ways to boost CAR T-cell therapy.
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Q&A With Eric Seaborg: Science Writer, Author, and Outdoorsman

Q&A With Eric Seaborg: Science Writer, Author, and Outdoorsman

Eric Seaborg Eric Seaborg, a writer and author, outdoorsman and environmentalist, has a love for hiking that he shared with his father, the late chemist and Nobel laureate... Read more ...

Project to Rapidly Sequence Maize Pangenome Delivers Publicly Available Resource

Project to Rapidly Sequence Maize Pangenome Delivers Publicly Available Resource

Matt Hufford, associate professor at Iowa State University, helped produce a 26-line maize pangenome assembly collection Maize researchers have been rejoicing over a New Year's... Read more ...

Epizyme's Soft Tissue Cancer Drug Granted Speedy FDA Approval

Epizyme's Soft Tissue Cancer Drug Granted Speedy FDA Approval

Epizyme won accelerated FDA approval Thursday for a drug developed to treat the rare cancer epithelioid sarcoma. The regulatory decision for the Epizyme drug, tazemetostat... Read more ...

The Wuhan Coronavirus Inspires a Look Back at the Discovery of Viruses

The Wuhan Coronavirus Inspires a Look Back at the Discovery of Viruses

I'm astonished at the speed with which geneticists and epidemiologists are zeroing in on the Wuhan coronavirus. Nomenclature is still up in the air. The first name, “2019-nCoV”... Read more ...

After AstraZeneca, Osbourn Reflects on Roles at CAT & MedImmune

After AstraZeneca, Osbourn Reflects on Roles at CAT & MedImmune

MedImmune, AstraZeneca's biologics division, is no more. The pharmaceutical giant announced last year that the name would be retired as part of a research and development... Read more ...

FDA Flags Risk of Infection, Kidney Damage for Sarepta Duchenne Drugs

FDA Flags Risk of Infection, Kidney Damage for Sarepta Duchenne Drugs

Safety concerns stymied Sarepta Therapeutics' attempt to win FDA approval last August for golodirsen , its second Duchenne muscular dystrophy drug. But an appeal of the... Read more ...

Horizon Gets Early FDA OK for First Thyroid Eye Disease Treatment

Horizon Gets Early FDA OK for First Thyroid Eye Disease Treatment

The first treatment for a rare disease that causes eye bulging and double vision received an FDA nod on Tuesday, weeks ahead of the agency's March 8 deadline to review the... Read more ...

Emendo Eyes the Clinic for CRISPR Therapy That Makes Single-Gene Edits

Emendo Eyes the Clinic for CRISPR Therapy That Makes Single-Gene Edits

CRISPR gene editing offers the potential to selectively edit the genetic mutations causing inherited diseases, but Emendo Biotherapeutics CEO David Baram contends it's not... Read more ...

CEOs of Women's Health Companies Fight to Open Investment Floodgates

CEOs of Women's Health Companies Fight to Open Investment Floodgates

Talking about sex with potential investors? For EvoFem Biosciences CEO Saundra Pelletier, it's the first item on the docket. Her company recently submitted Amphora, a... Read more ...

Bachem: EHS Coordinator

Bachem: Your Responsibilities The Environmental, Health and Safety Coordinator will be responsible for providing full time environmental health and sa Vista, CA, US ... Read more ...