Drugs

Composite Kernel Association Test for SNP-set Joint Assessment of Genotype and Genotype-by-treatment Interaction in Pharmacogenetics Studies

2 hours ago   |   Oxford Journals

AbstractIt is of substantial interest to discover novel genetic markers that influence drug response in order to develop personalized treatment strategies that maximize...
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Vanda Pharmaceuticals shares in the red as skin disease test fails

4 hours ago   |   Fierce Biotech

Vanda Pharmaceuticals is hoping to try again with an amended trial after its experimental skin drug tradipitant failed a phase 3 test.
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Takeda buys PvP in $330M deal to bag a second celiac drug

4 hours ago   |   Fierce Biotech

Takeda has exercised its option to buy PvP Biologics, adding another celiac disease candidate to its clinical pipeline. The Japanese drugmaker pulled the trigger on the deal...
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Uganda's Ministry of Health Officials Urge Government to Pass Biosafety Law

6 hours ago   |   ISAAA

Representatives from the Ministry of Health, Uganda Medical Association, the National Drug Authority, and Uganda Pharmaceutical Society resolved that the government should pass...
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AnaptysBio, Inc.: VP, Pharmacology & Toxicology

7 hours ago   |   San Diego Biotechnology   |   6 articles

AnaptysBio, Inc.: We are seeking a head of Pharmacology/Toxicology to lead a team in executing early clinical drug development activities evaluating the pharmacology an San...
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A drug discovery platform to identify compounds that inhibit EGFR triple mutants

11 hours ago   |   ACS Division of Biological Chemistry   |   2 articles

Nature Chemical Biology, Published online: 24 February 2020; doi:10.1038/s41589-020-0484-2 A high-throughput small-molecule drug screening platform enabled the detection of...
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Bicycle Therapeutics Lands $30M From Genentech in New Cancer R&D Pact

Bicycle Therapeutics Lands $30M From Genentech in New Cancer R&D Pact

19 hours ago   |   Xconomy

Genentech is the latest company to enter a drug discovery partnership with Bicycle Therapeutics, adding a new alliance in cancer research for the clinical-stage biotech. Under...
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Spherix Attends Artificial Intelligence and Machine Learning Pharmaceutical Development Conference

1 day ago   |   San Diego Biotechnology   |   2 articles

NEW YORK, Feb. 25, 2020 /PRNewswire/ - Spherix Incorporated today announced its attendance at the AI & ML Drug Discovery Summit. The AI-ML in Drug Development Summit is the...
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Kahr raises $18M to test CD47 drug with Roche's Tecentriq

1 day ago   |   Fierce Biotech

Kahr Medical has raised $18 million to take an anti-CD47 drug into the clinic. The money will fund early-phase development of a CD47x4-1BB bispecific that Kahr plans to test as...
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UK Reveals Plans For ‘Dynamic' Post-Brexit Regulatory System

UK Reveals Plans For ‘Dynamic' Post-Brexit Regulatory System

1 day ago   |   Xconomy

At the end of the Brexit transition period, the UK will be charting its own course through the often choppy seas of medicines regulation. While it plans to retain the existing...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

NGM Bio's NASH Drug Shows Promise, Shares Rise on Early Phase 2 Data

NGM Bio's NASH Drug Shows Promise, Shares Rise on Early Phase 2 Data

In what looks to be a transformative year for potential treatments of nonalcoholic steatohepatitis, the liver disease better known as NASH, another biotech has revealed that... Read more ...

Bicycle Therapeutics Lands $30M From Genentech in New Cancer R&D Pact

Bicycle Therapeutics Lands $30M From Genentech in New Cancer R&D Pact

Genentech is the latest company to enter a drug discovery partnership with Bicycle Therapeutics, adding a new alliance in cancer research for the clinical-stage biotech. Under... Read more ...

UK Reveals Plans For ‘Dynamic' Post-Brexit Regulatory System

UK Reveals Plans For ‘Dynamic' Post-Brexit Regulatory System

At the end of the Brexit transition period, the UK will be charting its own course through the often choppy seas of medicines regulation. While it plans to retain the existing... Read more ...

Esperion's FDA-Approved Cholesterol Drug Priced Even Lower Than Expected

Esperion's FDA-Approved Cholesterol Drug Priced Even Lower Than Expected

As Esperion Therapeutics steered its cholesterol-lowering drug through clinical testing and regulatory review, CEO Tim Mayleben did something unusual for a pharmaceutical... Read more ...

How Resident Microbes Restructure Body Chemistry

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Scientists create virus-resistant tomato plants

Researchers of Valencia's Polytechnic University and the Spanish National Research Council have used tools that regulate gene expression in order to produce tomato plants that... Read more ...

Researchers turn bacterial cell into biological computer

Researchers at the Technion have created a biological computer, constructed within a bacterial cell and capable of monitoring different substances in the environment... Read more ...

Connecting mathematical models to genomes: Joint estimation of model...

AbstractMotivationParameters of mathematical models used in biology may be genotype-specific and regarded as new traits. Therefore, an accurate estimation of these parameters... Read more ...

Discovering and interpreting transcriptomic drivers of imaging traits using...

AbstractMotivationCancer heterogeneity is observed at multiple biological levels. To improve our understanding of these differences and their relevance in medicine, approaches... Read more ...

Rhapsody: Predicting the pathogenicity of human missense variants

AbstractMotivationThe biological effects of human missense variants have been studied experimentally for decades but predicting their effects in clinical molecular diagnostics... Read more ...