DNA

Hypoxia-induced changes in intragenic DNA methylation correlate with alternative splicing in breast cancer

1 day ago   |   Journal of Biosciences   |   2 articles

Abstract The tumor microenvironment is marked by gradients in the level of oxygen and nutrients, with oxygen levels reaching a minimum at the core of the tumor, a condition...
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Rewiring E2 enzymes

1 day ago   |   ACS Division of Biological Chemistry   |   8 articles

Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0454-8 The site-specific monoubiquitination of FANCD2 is crucial for the Fanconi anemia DNA...
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Publisher Correction: An efficient gene knock-in strategy using 5′-modified double-stranded DNA donors with short homology arms

1 day ago   |   ACS Division of Biological Chemistry   |   8 articles

Nature Chemical Biology, Published online: 15 January 2020; doi:10.1038/s41589-020-0470-8 Publisher Correction: An efficient gene knock-in strategy using 5′-modified...
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Low doses of radiation used in medical imaging lead to mutations in cell cultures

1 day ago   |   ScienceDaily

Common medical imaging procedures use low doses of radiation that are believed to be safe. A new study, however, finds that in human cell cultures, these doses create breaks...
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Plasmonic Biosensor Controlled by DNAzyme for On‐site Genetic Detection of Pathogens

2 days ago   |   Wiley

On‐site pre‐detection of pathogens could significantly decrease of a disease outbreak or national loss in most of the countries. However, conventional detection techniques were...
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A novel approach for T7 bacteriophage genome integration of exogenous DNA

2 days ago   |   Journal of Biological Engineering

The comparatively small genome, well elucidated functional genomics and rapid life cycle confer T7 bacteriophage with great advantages for bio-application. Genetic manipulation...
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Research Associate II - Inovio Pharmaceuticals - San Diego, CA

3 days ago   |   San Diego Biotechnology   |   3 articles

Inovio is an innovative biotechnology company focused on the discovery, development, and commercialization of its synthetic DNA technology targeted against...From Inovio...
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HIFI: estimating DNA-DNA interaction frequency from Hi-C data at restriction-fragment resolution

3 days ago   |   Genome Biology

Hi-C is a popular technique to map three-dimensional chromosome conformation. In principle, Hi-C's resolution is only limited by the size of restriction fragments. However...
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Opening up DNA to delete disease

3 days ago   |   ScienceDaily

Protein editorial assistants are clearing the way for cut-and-paste DNA editors, like CRISPR, to access previously inaccessible genes of interest. Opening up these areas of the...
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Analyzing DNA in soil could be an effective way of tracking animals

3 days ago   |   ScienceDaily

Genetic material left behind by animals can provide critical clues to aid conservation and research. New research shows studying DNA in soil samples can be more effective...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Revolution Medicines Maps Out an IPO to Reach Cancer's Frontiers

Revolution Medicines Maps Out an IPO to Reach Cancer's Frontiers

Cancer research has revealed proteins known to play a role in the disease, but with no known way of stopping what they do. In pharmaceutical parlance, they're “undruggable.”... Read more ...

AveXis Inc.: Research Associate III

AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...

Mirati Therapeutics: Student Assistant

Mirati Therapeutics: Mirati Therapeutics is a targeted oncology company developing an advanced pipeline of breakthrough medicines for precisely defined patient populations San... Read more ...

Inhibition of lignification of Zizania latifolia with radio frequency...

Zizania latifolia is easily lignified after harvesting, leading to the degradation of food quality and commercial value. Thus, this study evaluated the effect of radio... Read more ...

Performance difference of graph-based and alignment-based hybrid error...

The error-prone third-generation sequencing long reads can be corrected by the high-quality second-generation sequencing short reads, which is referred to as hybrid error... Read more ...

CHROMATIX: computing the functional landscape of many-body chromatin...

Chromatin interactions are important for gene regulation and cellular specialization. Emerging evidence suggests many-body spatial interactions play important roles in... Read more ...

Bachem: Validation Engineer II, QA

Bachem: Your Responsibilities The Validation Engineer II fulfills a critical role in GMP operations. This individual must plan and execute validation studies, Vista, CA, US ... Read more ...

AveXis Inc.: Senior Scientist, Molecular Biology

AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...

Mirati Therapeutics: Talent Partner

Mirati Therapeutics: Reporting to the Head of Business, Culture and Talent this role will be partner with C-Level executive(s) and their staff. This role will be responsib San... Read more ...

Selective inhibition of matrix metalloproteinase 10 with a single-domain...

Since their discovery, the matrix metalloproteinase family of proteases have been considered as therapeutic targets in numerous diseases and disorders. Unfortunately, clinical... Read more ...