Chemicals

Recent advances of dendrimer in targeted delivery of drugs and genes to stem cells as cellular vehicles

2 days ago   |   Wiley

Abstract Stem cells can be used to repair dysfunctional and injured tissues by delivering therapeutics. However, in comparison with other cells, it is harder to transfect drugs...
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New screening method could lead to microbe-based replacements for chemical pesticides

2 days ago   |   Phys

Plants have evolved unique immunity mechanisms that they can activate upon detecting the presence of a pathogen. Interestingly, the presence of some nonpathogenic...
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Rethinking sustainability through synthetic biology

2 days ago   |   ACS Division of Biological Chemistry   |   2 articles

Nature Chemical Biology, Published online: 10 May 2021; doi:10.1038/s41589-021-00804-8 The use of bacterial biofilms provides a bioplastic that is biodegradable, water...
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Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo

2 days ago   |   ACS Division of Biological Chemistry   |   2 articles

Nature Chemical Biology, Published online: 10 May 2021; doi:10.1038/s41589-021-00786-7 The development of Sulfopin, a highly selective and potent, covalent Pin1 inhibitor that...
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Chemical compositions, antimicrobial effects, and cytotoxicity of Asia minor wormwood growing in Iran

4 days ago   |   Chemistry Central

Artemisia splendens from the Asteraceae family is a new source of biologically active compounds. The current study investigated to evaluate antimicrobial and cytotoxicity...
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Circularly permuted LOV2 as a modular photoswitch for optogenetic engineering

6 days ago   |   ACS Division of Biological Chemistry   |   3 articles

Nature Chemical Biology, Published online: 06 May 2021; doi:10.1038/s41589-021-00792-9 A set of LOV2 circular permutants have been engineered to expand the existing optogenetic...
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Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage

6 days ago   |   ACS Division of Biological Chemistry   |   3 articles

Nature Chemical Biology, Published online: 06 May 2021; doi:10.1038/s41589-021-00788-5 Liquid glycan arrays , presented on M13 bacteriophage surface proteins through...
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Architecture of the membrane-bound cytochrome c heme lyase CcmF

6 days ago   |   ACS Division of Biological Chemistry   |   3 articles

Nature Chemical Biology, Published online: 06 May 2021; doi:10.1038/s41589-021-00793-8 The structure of the heme lyase CcmF, an integral membrane protein, reveals a cavity...
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Molecular tweezers that attack antibiotic resistant bacteria

6 days ago   |   Phys

Researchers from Ben-Gurion University , together with American and German colleagues, have developed new "molecular tweezers" to combat antibiotic-resistant bacteria. Their...
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New tyrosinases with putative action against contaminants of emerging concern

6 days ago   |   Wiley

Abstract Tyrosinases are type‐3 copper metalloenzymes with strong oxidative capacities and low allosteric selectivity to phenolic and non‐phenolic aromatic compounds, which...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

PEPPRO: quality control and processing of nascent RNA profiling data

Nascent RNA profiling is growing in popularity; however, there is no standard analysis pipeline to uniformly process the data and assess quality. Here, we introduce PEPPRO, a... Read more ...

Enhanced cercosporin production by co-culturing Cercospora sp. JNU001 with...

Owing to the excellent properties of photosensitization, cercosporin, one of naturally occurring perylenequinonoid pigments, has been widely used in photodynamic therapy, or as... Read more ...

IAmScience Kulbir Sandhu

IAmScience Kulbir Sandhu

By Lauren Hines | Bond LSC Kulbir Sandhu's curiosity had guided him from place to place, but it was his fascination with plant science that has stayed the same. While Sandhu... Read more ...

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most produce antibodies in response to a pathogen or a vaccine. A small subset of B cells instead... Read more ...

Identifying collateral and synthetic lethal vulnerabilities within the...

A pair of genes is defined as synthetically lethal if defects on both cause the death of the cell but a defect in only one of the two is compatible with cell viability... Read more ...

Scientist - Emergent Biosolutions - San Diego, CA

The Scientist position supports the R&D teams to achieve company pipeline objectives by conducting research assignments involving a variety of laboratory...From Emergent... Read more ...

SSBER: removing batch effect for single-cell RNA sequencing data

With the continuous maturity of sequencing technology, different laboratories or different sequencing platforms have generated a large amount of single-cell transcriptome... Read more ...

Antimalarial Drug Resistance and Implications for the WHO Global Technical...

Abstract Purpose of Review Five years have passed since the World Health Organization released its Global Technical Strategy for Malaria. In that time, progress against malaria... Read more ...

Chloroplast genome analysis of Angiosperms and phylogenetic relationships...

Abstract Availability of comprehensive phylogenetic tree for flowering plants which includes many of the economically important crops and trees is one of the essential... Read more ...

Sr. Custom Applications Scientist - BD - San Diego, CA

Advanced design and development of assays including flow cytometry assays for assessment of cellular response to changes in the normal physiological make-up.From BD - Sat, 15... Read more ...