Biology

Cis-regulatory variation modulates susceptibility to enteric infection in the Drosophila genetic reference panel

1 day ago   |   Genome Biology   |   2 articles

Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel that...
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AveXis Inc.: Senior Scientist, Molecular Biology

1 day ago   |   San Diego Biotechnology

AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego...
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ShinyOmics: collaborative exploration of omics-data

2 days ago   |   BMC Bioinformatics

Omics-profiling is a collection of increasingly prominent approaches that result in large-scale biological datasets, for instance capturing an organism's behavior and response...
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Molecular basis for fibroblast growth factor 23 O -glycosylation by GalNAc-T3

2 days ago   |   ACS Division of Biological Chemistry   |   8 articles

Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0444-x Polypeptide GalNAc-transferase T3 catalyzes the specific glycosylation of...
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Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering

2 days ago   |   ACS Division of Biological Chemistry   |   8 articles

Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0445-9 A chemoproteomics and protein engineering strategy to investigate metabolic activity...
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A fungal family of lytic polysaccharide monooxygenase-like copper proteins

2 days ago   |   ACS Division of Biological Chemistry   |   8 articles

Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0438-8 The X325 protein family is highly similar to lytic polysaccharide monooxygenases in...
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Rewiring E2 enzymes

2 days ago   |   ACS Division of Biological Chemistry   |   8 articles

Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0454-8 The site-specific monoubiquitination of FANCD2 is crucial for the Fanconi anemia DNA...
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Lipid droplets can promote drug accumulation and activation

2 days ago   |   ACS Division of Biological Chemistry   |   8 articles

Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0447-7 Lasonolide A is hydrolyzed into a cytotoxic metabolite by a lipid droplet-associated...
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A lytic polysaccharide monooxygenase-like protein functions in fungal copper import and meningitis

2 days ago   |   ACS Division of Biological Chemistry   |   8 articles

Nature Chemical Biology, Published online: 13 January 2020; doi:10.1038/s41589-019-0437-9 In the fungal pathogen Cryptococcus neoformans, Bim1 is a copper-binding lytic...
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Author Correction: Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex

2 days ago   |   ACS Division of Biological Chemistry   |   8 articles

Nature Chemical Biology, Published online: 15 January 2020; doi:10.1038/s41589-020-0471-7 Author Correction: Structural basis of indisulam-mediated RBM39 recruitment to DCAF15...
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World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

World Biotechnology Congress 2019

Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...

2nd International Conference on Tissue Science and Regenerative Medicine

This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...

Interfacial molecular interactions of cellobiohydrolase Cel7A and its...

Molecular-scale mechanisms of the enzymatic breakdown of cellulosic biomass into fermentable sugars are still poorly understood, with a need for independent measurements of... Read more ...

Brassinosteroid overproduction improves lignocellulose quantity and quality...

As a leading biomass feedstock, poplar plants provide enormous lignocellulose resource convertible for biofuels and bio-chemicals. However, lignocellulose recalcitrance... Read more ...

US biofuel production and policy: implications for land use changes in...

It has been argued that the US biofuel policy is responsible for the land use changes in Malaysia and Indonesia. In this paper, following a short literature review that... Read more ...

Programmable nests for cells

Using DNA, smallest silica particles, and carbon nanotubes, researchers developed novel programmable materials. These nanocomposites can be tailored to various applications and... Read more ...

AveXis Inc.: Research Associate III

AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...

Mirati Therapeutics: Student Assistant

Mirati Therapeutics: Mirati Therapeutics is a targeted oncology company developing an advanced pipeline of breakthrough medicines for precisely defined patient populations San... Read more ...

Inhibition of lignification of Zizania latifolia with radio frequency...

Zizania latifolia is easily lignified after harvesting, leading to the degradation of food quality and commercial value. Thus, this study evaluated the effect of radio... Read more ...

Performance difference of graph-based and alignment-based hybrid error...

The error-prone third-generation sequencing long reads can be corrected by the high-quality second-generation sequencing short reads, which is referred to as hybrid error... Read more ...

CHROMATIX: computing the functional landscape of many-body chromatin...

Chromatin interactions are important for gene regulation and cellular specialization. Emerging evidence suggests many-body spatial interactions play important roles in... Read more ...

Bachem: Validation Engineer II, QA

Bachem: Your Responsibilities The Validation Engineer II fulfills a critical role in GMP operations. This individual must plan and execute validation studies, Vista, CA, US ... Read more ...