Biological
AstraZeneca Taps Gatehouse Bio to Identify Potential Drug Targets
51 minutes ago | Xconomy
After joining AstraZeneca's Boston Bio Hub incubator last year, Gatehouse Bio is now teaming up with the pharma company to identify potential drug targets in respiratory and...
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New Sanofi CEO Hudson adds next-gen cancer drug tech to the R&D quest, buying Synthorx for $2.5B
2 hours ago | San Diego Biotechnology | 2 articles
When Paul Hudson lays out his R&D vision for Sanofi tomorrow, he will have a new slate of interleukin therapies and a synthetic biology platform to boast about.
The French...
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The majority of A-to-I RNA editing is not required for mammalian homeostasis
4 hours ago | Springer
Abstract
Background
Adenosine-to-inosine RNA editing, mediated by ADAR1 and ADAR2, occurs at tens of thousands to millions of sites across mammalian transcriptomes. A-to-I...
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Three transcriptional regulators positively regulate the biosynthesis of polycyclic tetramate macrolactams in Streptomyces xiamenensis 318
6 hours ago | Springer
Abstract
Polycyclic tetramate macrolactams are a widely distributed class of structurally complex natural products, and most of them exhibit multiple biological activities...
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Bidirectional histone-gene promoters in Aspergillus: characterization and application for multi-gene expression
13 hours ago | Springer
Abstract
Background
Filamentous fungi are important producers of enzymes and bioactive secondary metabolites and are exploited for industrial purposes. Expression and...
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Synthorx, Inc.: Director, Quality Assurance
1 day ago | San Diego Biotechnology
Synthorx, Inc.:
Director, Quality Assurance Synthorx is a biopharmaceutical company dedicated to delivering new biologic medicines to patients suffering from cance
La Jolla, CA
...
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Scientists detail how chromosomes reorganize after cell division
1 day ago | ScienceDaily
Researchers have discovered key mechanisms and structural details of a fundamental biological process - how a cell nucleus and its chromosomal material reorganizes itself after...
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Link between vitamin A and brain response in Monarch butterflies
1 day ago | ScienceDaily
Biologists are making strides in understanding biological clock function in several model organisms and translating these studies into broader implications for human health.
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Computational design of G Protein-Coupled Receptor allosteric signal transductions
1 day ago | ACS Division of Biological Chemistry | 4 articles
Nature Chemical Biology, Published online: 02 December 2019; doi:10.1038/s41589-019-0407-2 A computational approach for designing GPCRs with new signaling functions including...
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Guided nuclear exploration increases CTCF target search efficiency
1 day ago | ACS Division of Biological Chemistry | 4 articles
Nature Chemical Biology, Published online: 02 December 2019; doi:10.1038/s41589-019-0422-3 Single-particle tracking and mathematical modeling methods reveal the searching...
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World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
World Biotechnology Congress 2019
Hilaris Conferences is going to host its premier World Biotechnology Congress 2019 during October 01-02, 2019, Valencia, Spain. Biotechnology 2019 Congress aim to create a... Read more ...
2nd International Conference on Tissue Science and Regenerative Medicine
This conference is designed for experts in academia and industries working in the tissue science and regenerative field, this conference will examine cutting-edge research in... Read more ...
AstraZeneca Taps Gatehouse Bio to Identify Potential Drug Targets
After joining AstraZeneca's Boston Bio Hub incubator last year, Gatehouse Bio is now teaming up with the pharma company to identify potential drug targets in respiratory and... Read more ...
IAmScience Mannie Liscum
For Mannie Liscum, thinking is a privilege, and his job gives him the chance to be fascinated by human's capacity to conceptualize and learn new things. “It's my goal to use as... Read more ...
Alert: Johnson Fistel Investigates Proposed Sale of ArQule, Inc.; Is $20 a...
SAN DIEGO, Dec. 9, 2019 /PRNewswire/ - Shareholder rights law firm Johnson Fistel, LLP has launched an investigation into whether the board members of ArQule, Inc. breached... Read more ...
New Sanofi CEO Hudson adds next-gen cancer drug tech to the R&D quest...
When Paul Hudson lays out his R&D vision for Sanofi tomorrow, he will have a new slate of interleukin therapies and a synthetic biology platform to boast about. The French... Read more ...
AveXis Inc.: Senior Scientific Training Specialist - cGMP Gene Therapy
AveXis Inc.: OverviewReady to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological gene San Diego... Read more ...
Process Engineer I - Genentech - Oceanside, CA
Focus will be on one or more areas such as design, implementation and/or start-up of new and/or existing facilities with respect to process and/or clean utility...From... Read more ...
Pineoblastoma segregates into molecular sub-groups with distinct...
Abstract Pineoblastomas are rare, aggressive pediatric brain tumors of the pineal gland with modest overall survival despite intensive therapy. We sought to define the clinical... Read more ...
The majority of A-to-I RNA editing is not required for mammalian homeostasis
Abstract Background Adenosine-to-inosine RNA editing, mediated by ADAR1 and ADAR2, occurs at tens of thousands to millions of sites across mammalian transcriptomes. A-to-I... Read more ...
CRISPR System: A High-throughput Toolbox for Research and Treatment of...
Abstract In recent years, the innovation of gene-editing tools such as the CRISPR/Cas9 system improves the translational gap of treatments mediated by gene therapy. The... Read more ...
Exploration of cryptic organic photosensitive compound as Zincphyrin IV in...
Abstract Zincphyrin IV is a potential organic photosensitizer which is of significant interest for applications in biomedicine, materials science, agriculture , and chemistry... Read more ...